Leptin

Leptin

Author
V. Daniel Castracane, Michael C. Henson
Publication Year
2007
Publisher
Springer
Language
English
Document Type
Book
Faculty / Subject Heading
Medical Science

The discovery of leptin little more than a decade ago, as a hormone produced in white adipose tissue with an important role in satiety and energy expenditure, was a seminal event in our understanding of adiposity. This initial advance in the new endocrinology of obesity was soon followed by the realization that leptin was not only produced in adipose tissue, but in many different tissues of the body, and that receptors were similarly distributed. Additionally, the early recognition of infertility that was associated with leptin deficiency prompted research that identified roles for the polypeptide in virtually every area of reproductive biology.


Keywords: Medicine / Bone / Hormone / Leptin receptors / Metabolism / Neuroendocrinology / Obesity / Physiology / Protein / Reproduction