Book Details

The Molecular Mechanisms of Axenfeld-Rieger Syndrome

Publication year: 2005

ISBN: 978-0-387-28672-3

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Annotation The Molecular Mechanisms of Axenfeld-Rieger Syndrome describes the current research and clinical findings of the heterogeneous disorder termed Axenfeld-Rieger Syndrome (ARS). The book provides an in-depth analysis of this phenotypic diverse disorder and is designed to detail the current molecular and biochemical research involved in studying genetic defects. This book brings together the complete analysis of a human genetic defect using humans, mouse and chick epigenetic and genetic studies, combined with cell culture and in vitro analyses. It is a comprehensive study of a unique set of genes and their mutant activities. A molecular basis for the genetic and phenotypic anomalies observed in ARS patients is provided, with especially detailed descriptions of eye, tooth, and heart development.


Subject: Biomedical and Life Sciences, Genes, In vitro analyses, Molecular Mechanisms, Mouse, Mutant, Transcription