Immobilisation of DNA on Chips I
Publication year: 2005
ISBN: 978-3-540-31456-1
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the main focus of these two volumes is on the immobilization chemistry, considering the various aspects of the immobilization process itself, since different types of nucleic acids, support materials, surface activation chemistries and patterning tools are of key concern.the focus of the major part of the chapters lies on the coupling chemistry used for DNA immobilization. Successful immobilization techniques for DNA appear to either involve a multi-site attachment of DNA (preferentially by electrochemical and/or physical adsorption) or a single-point attachment of DNA (mainly by surface activation and covalent immobilization or (strept)avidin-biotin linkage).
Subject: Chemistry and Materials Science, DNA, Nucleotide, Biochemistry, Chips, Inorganic Chemistry, Organic Chemistry
