Publication year: 2022
ISBN: Ph00197
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From the earliest days of the COVID-19 pandemic, there have been reports of significant neurological and psychological symptoms following SARS-CoV-2 infection. This research paper is designed to examine the potential psychoneuroendocrine pathogenic mechanisms by which SARS-CoV-2 elicits psychiatric sequelae, as well as to posit potential pharmacologic strategies to address and reverse these pathologies. Following a brief overview of the presence and prevalence of neuropsychiatric manifestation in COVID-19 patients, we address mechanisms by which SARS-CoV-2 could enter or otherwise elicit changes in the CNS.
Subject: COVID‐19, Coronavirus, Infectious diseases, SARS-CoV-2, Anosmia, Neuroinvasion, Nervous system, Pathogenesis, Neuroinflammation