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Depression is a serious medical illness. It's more than just feeling of being sad or "blue" for a few days. If you are one the more 19 million teens and adults in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life. Depression is a disorder of the brain. There with your everyday life. Depression is a disorder of the brain. There are a variety of causes, including genetic, biological, environmental, and psychological factors. Depression can happen at any age, but it often begins in teens and young adults. It is much more common in women. Women can also get postpartum depression after the birth of a baby. Some people get seasonal affective disorder in the winter.