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Multiple sclerosis (MS) is the most common inflammatory degenerative disease of the central nervous system in young adults. To date, the disease cannot be cured. A number of new therapeutic options have emerged in recent years. The aim of this white paper is to present current knowledge about the disease MS and its care in Germany objectively and comprehensively. It contains Information on the clinical picture, on the epidemiology and on its health-economic relevance. Current developments and treatment recommendations are compared to the real use and the existing capacities of diagnostic and therapeutic options.