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Feasibility and Infeasibility in Optimization is a timely expository book that summarizes the state of the art in both classical and recent algorithms related to feasibility and infeasibility in optimization, with a focus on practical methods. All model forms are covered, including linear, nonlinear, and mixed-integer programs. Connections to related work in constraint programming are shown. Part I of the book addresses algorithms for seeking feasibility quickly, including new methods for the difficult cases of nonlinear and mixed-integer programs. Part II provides algorithms for analyzing infeasibility by isolating minimal infeasible (or maximum feasible) subsets of constraints, or by finding the best repair for the infeasibility. Infeasibility analysis algorithms have arisen primarily over the last two decades, and the book covers these in depth and detail. Part III describes applications in numerous areas outside of direct infeasibility analysis such as finding decision trees for data classification, analyzing protein folding, radiation treatment planning, automated test assembly, etc.