Book Details

The Cancer Degradome

Publication year: 2008

ISBN: 978-0-387-69057-5

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proteolysis is now known to be integral to many aspects of cancer biology,including angiogenesis, regulation of the bioavailability of growth factors, cellular adhesion, cytokine/chemokine signalling, inflammatory cell recruitment, and the mobilization of normal cells from their tissue compartments to act as accomplicesin metastasis. The last decade has witnessed a revolution in our thinking concerning the role of extracellular proteolysis in cancer biology: this is the primary focus of this book.


Subject: Biomedical and Life Sciences, CLIP-CHIP, Microarray, PCR, angiogenesis, cysteine cathepsin, degradome, gene expression, genes, imaging, mass spectrometry, migration, plasminogen, regulation, tissue, transplantation