Book Details

Stress-Activated Protein Kinases

Publication year: 2008

ISBN: 978-3-540-75569-2

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To maximize the probability of survival, cells need to coordinate their intracellular activities in response to changes in the extracellular environment. MAP kinase cascades play an important role in the transduction of signals inside eukaryotic cells. In particular, stress stimuli result in the rapid activation of a highly conserved group of MAP kinases, known as SAPKs (Stress-Activated Protein Kinases). These kinases coordinate the generation of adaptive responses that are essential for cell survival, which include the modulation of several aspects of cell physiology from metabolism to gene expression.


Subject: Biomedical and Life Sciences, Activation, Cell Cycle Regulation, Kinase, Phosphorylation, Signalling, Stress Adaptation, Stress Response, gene expression, metabolism, regulation, saccharomyces cerevisiae, transcription, translation