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Serotonin and Sleep: Molecular, Functional, and Clinical Aspects covers the complete spectrum of the field and explores the link between the latest basic molecular, functional, and clinical aspects of serotonin and the practice of sleep medicine. The volume focuses on 24 different areas of research, with special emphasis relating the state of basic and clinical research to potential applications: changing concepts in serotonin research, topographic organization and chemoarchitecture, receptor mechanisms – its organization and regulation of behavioral states, electrophysiological mechanisms – in vitro, in vivo, and behaving animals and other areas of molecular neurobiology. Also highlighted are studies related to the circadian control of behavioral states, and mechanisms involved in the serotonergic inhibition of REM sleep. Such discussion has profound implications for the basic biology of serotonin.