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Reviews the second five-year sequence of the Chair, first presenting methodological advances in eco-design: life cycle assessment and quantification of uncertainties; local environmental impacts of transport and biodiversity. The interdisciplinary partnership, also associating the human sciences, shows its interest in taking into account the human factor in the modelling of urban systems. This modelling is based on several numerical simulation tools, presented in the third part. This theoretical set results in more substantial proposals for the renewal of techniques and systems, in terms of energy management strategies in buildings, urban agriculture, participatory data collection and digital transformation in transport.