Book Details

978-1-0716-1944-5

Immune receptors : methods and protocols / Jonathan Patrick Rast, Katherine Buckley

Publication year: 2022

ISBN: 978-1-0716-1944-5

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Explores immune cell receptors that are used in the detection of microbes, either by binding directly to non-self molecules or through indirectly sensing microbe-associated cellular disturbances. The covers methods for studying receptor-ligand interactions at both molecular and cellular levels; methods to create and characterize novel antibody reagents; and methods to characterize the molecular processes that lead to adaptive receptor maturation. This book also contains chapters that look at high-throughput strategies that describe the diversity of immune receptors and cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Subject: Immunology, Cell Biology, Lectin-Like Receptors, Immunoglobulin Fc Regions, Membrane-Bound Chemokine, Mass Spectrometry-Based Proteomics, immune response