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The most recent outbreak in the twenty-first century is the highly pathogenic human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently recognized in Wuhan, China, as the cause of the coronavirus disease 2019 (COVID-19) outbreak which has spread rapidly from China to other countries in the world, causing a pandemic with alarming morbidity and mortality. Therefore, the goal of our project is to highlight first of all the value of vaccine in terminating all of the historical previous pandemics including Aids since the first vaccine against it had received FDA approval several days ago therefore, we will review in our.