Publication year: 2018
ISBN: 1118145666
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A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author-a noted expert in the field-includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest.
Subject: Pharmaceutical chemistry, Chemistry, Pharmaceutical, Chemistry, Pharmaceutical methods, Chimie pharmaceutique, Drug Discovery methods, Drug development Methodology, Medical Pharmacology, Médicaments Développement Méthodologie, Molecular Structure, Molecular structure, Structure moléculaire, Benzodiazepines, Dihydropyridines, Biaryls, Spiropiperidines, Aminopyrimidines, Aminothiazoles, Tetrahydroisoquinolines, Dimethylbenzopyrans, Hydroxamates