Book Details

NoIMG

Biomarkers in Drug Discovery and Development: A Handbook of Practice, Application, and Strategy / Ramin Rahbari, Jonathan Van Niewaal, Michael R. Bleavins

Publication year: 2020

ISBN: 1119187508

Internet Resource: Please Login to download book


Discusses biomarker characterization and validation and applications throughout drug discovery and development. Explains where proper use of biomarkers can substantively impact drug development timelines and costs, enable selection of better compounds and reduce late stage attrition, and facilitate personalized medicine. Helps readers get a better understanding of biomarkers and how to use them, for example which are accepted by regulators and which still non-validated and exploratory. Updates developments in genomic sequencing, and application of large data sets into pre-clinical and clinical testing; and adds new material on data mining, economics, and decision making, personal genetic tools, and wearable monitoring. Includes case studies of biomarkers that have helped and hindered decision making


Subject: Pharmaceutical and Medicinal Chemistry, Drug Discovery and Development, Drug Discovery, Drug Design and Development, Pharmaceutical Science Regulatory, Pharmacology, Pharmacokinetics