Book Details


Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives / Jesús Fernández Lucas

Publication year: 2019

ISBN: 3527343768

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The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications.

Subject: Chemistry, Biochemistry (Chemical Biology), Chemical synthesis, Enzyme catalysis