Book Details


Biomarkers for Alzheimer’s Disease Drug Development / Robert Perneczky

Publication year: 2018

ISBN: 978-1-4939-7704-8

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Aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer’s disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer’s disease, cutting-edge developments in neuropathology and their relevance for Alzheimer’s disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Subject: Pharmacology, Toxicology, Pharmacy, Disease-orientation, Alzheimer’s disease (AD), Cerebrospinal fluid, Blood-based biomarkers, Magnetic resonance imaging, Neuropathology, Biomarker development