Book Details


EGFR Signaling Networks in Cancer Therapy

Publication year: 2008

ISBN: 978-1-59745-356-1

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EGFR Signaling Networks in Cancer Therapy, is separated into two sections. The first of which probes the molecular pathways and the intersection of signaling networks which are frequently deregulated in human cancers, the second section illustrates the many ways in which EGF receptor contribute to abnormal survival and migration signaling in cancer cells and to epithelial to mesenchymal transition and metastasis.

Subject: Medicine, EGFR, STAT 3, Signaling networks, angiogenesis, enzymes, glioblastoma, heterodimerization, inhibitors, kinase domain, solid tumors, tumorigenesis