Reviews of Physiology, Biochemistry and Pharmacology ; volume 158
Publication year: 2007
ISBN: 978-3-540-71791-1
Internet Resource: Please Login to download book
The cells of the renal proximal tubule have a high capacity for uptake of proteins filtered in the glomeruli, reflected by an extensively developed endocytic apparatus and the normal very low urinary excretion of plasma proteins. The cutoff molecular mass for glomerular filtration of plasma proteins under physiological conditions is generally considered to be in the range of 60 kDa, corresponding approximately to the molecular mass of serum albumin.
Subject: Biomedical and Life Sciences, TRPM5, TRPM6, biochemistry, chloride transport proteins, cubilin, ion channels, megalin, pathophysiology, physiology
