Book Details

978-3-540-36689-8

Genetic Control of Neuronal Migrations in Human Cortical Development

Publication year: 2007

ISBN: 978-3-540-36689-8

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Introduction Cortical development is a complex, tightly regulated process that eventually leads to the six-layered adult human neocortex, the substrate of the unique cognitive, emotional, and social abilities of our species. The basic mechanisms of early cortical development are believed to be very similar among mammals, which has led to a tendency of extrapolating experimental data from rodents on humans.


Subject: Biomedical and Life Sciences, Cajal-Retzius cells, Cortex, Neuron, Reelin, axonal pathways, cortical gyration, cortical lamination, cortical plate, cortical wall, genes, lissencephaly, neuronal differentiation, neuronal migration