Conditional Mutagenesis: An Approach to Disease Models
Publication year: 2007
ISBN: 978-3-540-35109-2
Internet Resource: Please Login to download book
Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.
Subject: Biomedical and Life Sciences, Chromosom, conditional mutagenesis, cre recombinase, drug development, gene knockout, genes, molecular mechanism, smouse models of human diseases, pathophysiology, physiology
