Book Details

Vaccine Adjuvants

Publish Date: 2006

ISBN: 978-1-59259-970-7

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The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

Subject: Biomedical and Life Sciences, Antigen, bacteria, genes, lipide, parasite, parasites, pathogenesis, protein, research, vaccine