Book Details

Cell Culture Engineering

Publication year: 2006

ISBN: 978-3-540-34007-2

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Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the first generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the first p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modifications on proteins could only be efficiently carried out in mammalian cells.

Subject: Chemistry and Materials Science, Biotechnology, Cell Culture, Escherichia coli, biochemical engineering, cell biology, post-translational modification, protein, proteins, translation