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Presents the main statistical tools useful in genetics: significance tests, analysis methods based on the likelihood function, EM algorithm, modeling, analysis of variance, hierarchical classifications, multiple comparisons, etc. All of them shed light on a number of biological phenomena such as carcinogenesis, population genetics, Hardy-Weinberg equilibrium, natural selection, mutations, heredity, coalescence processes, and even evolution. This book is intended for mathematicians and biologists alike. Written with a great concern for clarity, it is also accessible to non-specialists who will be able, thanks to it, to strengthen their theoretical base and above all to develop their know-how through very concrete applications.