Publication year: 2006
ISBN: 978-1-59745-085-0
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Despite significant pharmacological advances, the backbone of the most highly active antiretroviral therapy regimens for controlling HIV/AIDS is still a combination of reverse transcriptase inhibitors (RTIs) first discovered in the late 1980s. In Reverse Transcriptase Inhibitors in HIV/AIDS Therapy, leading experts in AIDS/HIV drug discovery and development review all aspects of RTIs (nucleosides, nucleotides, and non-nucleosides), including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS.
Subject: Medicine, AIDS, HIV, HIV, AIDS, drug, drug discovery, drug resistance, kinetics, pharmacokinetics, pharmacology, prevention, resistance, toxicity