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Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.
Heavy-Tailed Time Series
This book aims to present a comprehensive, self-contained, and concise overview of extreme value theory for time series, incorporating the latest research trends alongside classical methodology.Additionally, the book incorporates complete proofs and exercises with solutions as well as substantive reference lists and appendices, featuring a novel commentary on the theory of vague convergence.
HCI in games : Experience design and game mechanics ; Third International Conference, HCI-Games 2021, Held as Part of the 23rd HCI International Conference, HCII 2021, Virtual Event, July 24–29, 2021, Proceedings, Part I
This two-volume set LNCS 12789 and 12790 constitutes the refereed proceedings of the Third International Conference on HCI in Games, HCI-Games 2021, held as part of the 23rd International Conference, HCI International 2021, which took place in July 2021. Due to COVID-19 pandemic the conference was held virtually.The total of 1276 papers and 241 poster papers included in the 39 HCII 2021 proceedings volumes was carefully reviewed and selected from 5222 submissions. The regular papers of DAPI 2021, Distributed, Ambient and Pervasive Interactions, are organized in topical sections named: Experience Design in Games; User Engagement and Game Impact; Game Mechanics.
Hardy Inequalities on Homogeneous Groups : 100 Years of Hardy Inequalities
This book provides an extensive treatment of Hardy inequalities and closely related topics from the point of view of Folland and Stein's homogeneous (Lie) groups. The place where Hardy inequalities and homogeneous groups meet is a beautiful area of mathematics with links to many other subjects.In this environment, the theory of Hardy inequalities becomes intricately intertwined with the properties of sub-Laplacians and subelliptic partial differential equations.
Handbook Of Mathematical Models For Languages And Computation
Introduces a variety of concepts in discrete mathematics and mathematical modeling for languages and computation. The authors pay special attention to the implementation of mathematical concepts to explain clearly how to encode them in computational practice. All computer programs are written in C#. The theory of computation is used to address challenges arising in many computer science areas such as artificial intelligence, language processors, compiler writing, information and coding systems, programming language design, computer architecture and more. To grasp topics concerning this theory readers need to familiarize themselves with its computational and language models, based on concepts of discrete mathematics including sets, relations, functions, graphs and logic.
Handbook of Fractional Calculus for Engineering and Science
Provides reliable methods for solving fractional-order models in science and engineering. Contains efficient numerical methods and algorithms for engineering-related equations. Contains comparison of various methods for accuracy and validity. Demonstrates the applicability of fractional calculus in science and engineering. Examines qualitative as well as quantitative properties of solutions of various types of science- and engineering-related equations.
Guide to Deep Learning Basics : Logical, Historical and Philosophical Perspectives
This stimulating text/reference presents a philosophical exploration of the conceptual foundations of deep learning, presenting enlightening perspectives that encompass such diverse disciplines as computer science, mathematics, logic, psychology, and cognitive science. The text also highlights select topics from the fascinating history of this exciting field, including the pioneering work of Rudolf Carnap, Warren McCulloch, Walter Pitts, Bulcsú László, and Geoffrey Hinton.
Graph-theoretic concepts in computer science ; Vol. 3787 ; 31st International Workshop, WG 2005, Metz, France, June 23-25, 2005, Revised Selected Papers
that aims to unite theory and practice by demonstrating how graph-theoretic concepts can be applied to various areas in Computer Science. This book provides results for various classes of graphs, graph computations, graph algorithms, and graph-theoretical applications in various fields.
Graph-theoretic concepts in computer science ; 34th International Workshop, WG 2008, Durham, UK, June 30 – July 2, 2008. Revised Papers
This book constitutes the thoroughly refereed post-conference proceedings of the 34th International Workshop on Graph-Theoretic Concepts in Computer Science, WG 2008, held in Durham, UK, in June/July 2008.The 30 revised full papers presented together with 3 invited paper were carefully reviewed and selected from 76 submissions. The papers feature original results on all aspects of graph-theoretic concepts in Computer Science, e.g. structural graph theory, sequential, parallel, and distributed graph and network algorithms and their complexity, graph grammars and graph rewriting systems.
Graph-based Knowledge Representation : Computational Foundations of Conceptual Graphs
This book studies a graph-based knowledge representation and reasoning formalism stemming from conceptual graphs, with a substantial focus on the computational properties.Knowledge can be symbolically represented in many ways, and the authors have chosen labeled graphs for their modeling and computational qualities. the authors have attempted to answer, the following question:`how far is it possible to go in knowledge representation and reasoning by representing knowledge with graphs and reasoning with graph operations?''
Graph drawing ; 15th International symposium, GD 2007, Sydney, Australia, September 24-26, 2007. Revised Papers
The 16th International Symposium on Graph Drawing (GD 2008) was held in Hersonissos, near Heraklion, Crete, Greece, September 21-24, 2008, and was attended by 91 participants from 19 countries. In response to the call for papers the Program Committee received 83 s- missions,eachdescribing originalresearchand/or a systemdemonstration.Tamassia showed how graph drawing techniques can be used as an e?ective tool in computer security and pointed to future research directions in this area. Following what is now a tradition, the 15th Annual Graph Drawing Contest was held during the conference, also including a Graph Drawing Challenge to the conference attendees.
Global mobile satellite communications : For maritime, Land and aeronautical applications
This book is important for modern shipping, truck, train and aeronautical societies because GMSC in the present millennium provides more effective business and trade, with emphasis on safety and commercial communications. Global Mobile Satellite Communications is written to make bridges between potential readers and current GMSC trends, mobile system concepts and network architecture using a simple mode of style with understandable technical information, characteristics, graphicons, illustrations and mathematics equations
Geometric Properties for Incomplete Data
Computer vision and image analysis require interdisciplinary collaboration between mathematics and engineering. This book addresses the area of high-accuracy measurements of length, curvature, motion parameters and other geometrical quantities from acquired image data. It is a common problem that these measurements are incomplete or noisy, such that considerable efforts are necessary to regularise the data, to fill in missing information, and to judge the accuracy and reliability of these results. This monograph brings together contributions from researchers in computer vision, engineering and mathematics who are working in this area.
Geographic Information Science ; 4th International Conference, GIScience 2006, Münster, Germany, September 20-23, 2006, Proceedings
The GIScience conference series (www. giscience. org) was created as a forum for all researchers who are interested in advancing research in the fundam- tal aspects of geographic information science.The conferences focus on emerging topics and basic research ?ndings across all s- tors of geographic information science. After three highly successful conferences in the United States, this year’s GIScience conference was held in Europe for the ?rst time. The GIScience conferences have been a meeting point for researchers coming from various disciplines, including cognitive science, computer science, engine- ing, geography,information science, mathematics, philosophy, psychology,social science, and statistics. The advancement of geographic information science - quiressuchinterdisciplinarybreadth,andthisisalsowhatmakestheconferences so exciting. In order to account for the di?erent needs of the involved scienti?c disciplines with regard to publishing their research results.
Fuzzy Logic with engineering applications
Latest advances in the field including material on expansion of the MLFE method using genetic algorithms, cognitive mapping, fuzzy agent-based models and total uncertainty. Redundant or obsolete topics have been removed, resulting in a more concise yet inclusive text that will ensure the book retains its broad appeal at the forefront of the literature.
Fundamental approaches to software engineering ; 23rd International Conference, FASE 2020, Held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2020, Dublin, Ireland, April 25–30, 2020, Proceedings
This book constitutes the proceedings of the 23rd International Conference on Fundamental Approaches to Software Engineering, FASE 2020, which took place in Dublin, Ireland, in April 2020, and was held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2020. The 23 full papers, 1 tool paper and 6 testing competition papers presented in this volume were carefully reviewed and selected from 81 submissions.
Functional imaging and modeling of the heart ; 3rd International workshop, FIMH 2005, Barcelona, Spain, June 2-4, 2005, Proceedings
The FIMH conference was the ?rst attempt to agglutinate researchers from several complementary but often i- lated ?elds: cardiac imaging, signal and image processing, applied mathematics and physics, biomedical engineering and computer science, cardiology, radi- ogy, biology, and physiology. In the ?rst two editions, the conference received an enthusiastic acceptance by experts of all these communities. FIMH was ori- nally started as a European event and has increasingly attracted more and more people from the US and Asia. This edition of FIMH received the largest number of submissions so far with a result of 47 papers being accepted as either oral presentations or posters. There were a number of submissions from non-EU institutions which con?rms the growing interest in this series of meetings. All papers were reviewed by up to four reviewers. The accepted contributions were organized into 8 oral sessions and 3 poster sessions complemented by a number of invited talks. This year we tried to allocate as many papers as possible as oral presentations to facilitate more active participation and to stimulate multidisciplinary discussions.
FSTTCS 2006 : Foundations of software technology and theoretical computer science ; 26th International Conference, Kolkata, India, December 13-15, 2006, Proceed
This book constitutes the refereed proceedings of the 26th International Conference on the Foundations of Software Technology and Theoretical Computer Science, FSTTCS 2006, held in Kolkata, India, in December 2006. It contains 38 papers that cover a broad variety of current topics from the theory of computing, ranging from formal methods, discrete mathematics, complexity theory, and automata theory to theoretical computer science in general.
Frontiers in Algorithmics ; 2nd Annual International Workshop, FAW 2008, Changsha, China, June 19-21, 2008, Proceeedings
This book constitutes the refereed proceedings of the Second International Frontiers of Algorithmics Workshop, FAW 2008, held in Changsha, China, in June 2008.The 33 revised full papers presented together with the abstracts of 3 invited talks were carefully reviewed and selected from 80 submissions. The papers were selected for 9 special focus tracks in the areas of biomedical informatics, discrete structures, geometric information processing and communication, games and incentive analysis.
Frontiers in Algorithmics ; 14th International Workshop, FAW 2020, Haikou, China, October 19-21, 2020, Proceedings
This book constitutes the proceedings of the 14th International Workshop on Frontiers in Algorithmics, FAW 2020, held in Haikou, China, in May 2020. The conference was held virtually due to the COVID-19 pandemic. The 12 full papers presented in this volume were carefully reviewed and selected from 15 submissions. The workshop provides a focused forum on current trends of research on algorithms, discrete structures, and their applications, and brings together international experts at the research frontiers in these areas to exchange ideas and to present significant new results. The papers detail graph theory, scheduling and algorithm and complexity.
