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The growing scientific interest of pomegranate is due to the functional properties produced for its Phenolic compounds. The term “functional” is understood as the potentially positive effect of a food on health beyond basic nutrition. It contains hydrolysable tannins, condensed tannins, flavonols, anthocyanins, and phenolic and organic acids. Pomegranate, being rich in bioactive compounds like polyphenols, has shown many health-related properties, such as antioxidant, anti-inflammatory and antihypertensive, through in vivo and in vitro studies. Several studies have brought up the potential contribution of pomegranate in the treatment of cancer, diabetes and heart disease.