الصفحة 1
الصفحة 1
Nuucleic acids in medicinal chemistry and chemical biology : Drug development and clinical applications
Delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers. The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field
Number Theory ; Vol.15 : Tradition and Modernization
This book appears varied, they are unified by two underlying principles:first, making everything readable as a book, and second, making a smooth transition from traditional approaches to modern ones by providing a rich array of examples. The chapters are presented in quite different in depth and cover a variety of descriptive details.The book emphasizes a few common features such as functional equations for various zeta-functions, modular forms, congruence conditions, exponential sums, and algorithmic aspects.
Nonlinear finite element analysis of composite and reinforced concrete beams
Nonlinear Finite Element Analysis of Composite and Reinforced Concrete Beams presents advanced methods and techniques for the analysis of composite and FRP reinforced concrete beams. The title introduces detailed numerical modeling methods and the modeling of the structural behavior of composite beams, including critical interfacial bond-slip behavior. It covers a new family of composite beam elements developed by the authors. Other sections cover nonlinear finite element analysis procedures and the numerical modeling techniques used in commercial finite element software that will be of particular interest to engineers and researchers executing numerical simulations.
Neural Networks : Computational Models and Applications
Neural Networks: Computational Models and Applications covers a wealth of important theoretical and practical issues in neural networks, including the learning algorithms of feed-forward neural networks, various dynamical properties of recurrent neural networks, winner-take-all networks and their applications in broad manifolds of computational intelligence: pattern recognition, uniform approximation, constrained optimization, NP-hard problems, and image segmentation. By presenting various computational models, this book is developed to provide readers with a quick but insightful understanding of the broad and rapidly growing areas in the neural networks domain. Besides laying down fundamentals on artificial neural networks, this book also studies biologically inspired neural networks. Some typical computational models are discussed, and subsequently applied to objection recognition, scene analysis and associative memory. The studies of bio-inspired models have important implications in computer vision and robotic navigation, as well as new efficient algorithms for image analysis.
Networking and Mobile Computing ; 3rd International Conference, ICCNMC 2005, Zhangjiajie, China, August 2-4, 2005, Proceedings
The objective of this conference was to address and capture highly innovative and stateof-the-art research and work in the networks and mobile computing industries. ICCNMC 2005 allowed sharing of the underlying theories and applications, and the establishment of new and long-term collaborative channels aimed at developing innovative concepts and solutions geared to future markets. The highly positive response to ICCNMC 2001 and ICCNMC 2003, held in Beijing and Shanghai, respectively, encouraged us to continue this international event. In its third year, ICCNMC 2005 continued to provide a forum for researchers, professionals, and industrial practitioners from around the world to report on new advances in computer network and mobile computing, as well as to identify issues and directions for research and development in the new era of evolving technologies.
Natural Products : Drug Discovery and Therapeutic Medicine
Although the natural product drug discovery programs of the large drug companies are now equaled by programs for the high throughput screening of synthetic compounds generated through combinatorial chemistry, natural compounds still hold great promise to overcome such problems as antibiotic resistance, the emergence of new diseases, the failure to conquer old diseases, and the toxicity of some contemporary medical products. In Natural Products: Drug Discovery and Therapeutic Medicine, a panel of recognized experts and leaders in the field discuss the past successes of natural products as medicines and review future possibilities arising from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discovery, to accessing microbial diversity, to investigating specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to exploiting specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Natural Language Processing and Chinese Computing ; 9th CCF International Conference, NLPCC 2020, Zhengzhou, China, October 14–18, 2020, Proceedings, Part II
This two-volume set of LNAI 12340 and LNAI 12341 constitutes the refereed proceedings of the 9th CCF Conference on Natural Language Processing and Chinese Computing, NLPCC 2020, held in Zhengzhou, China, in October 2020. The 70 full papers, 30 poster papers and 14 workshop papers presented were carefully reviewed and selected from 320 submissions. They are organized in the following areas: Conversational Bot/QA; Fundamentals of NLP; Knowledge Base, Graphs and Semantic Web; Machine Learning for NLP; Machine Translation and Multilinguality; NLP Applications; Social Media and Network; Text Mining; and Trending Topics.
Natural language processing and chinese computing ; 9th CCF International conference, NLPCC 2020, Zhengzhou, China, October 14–18, 2020, Proceedings, Part I
This two-volume set of LNAI 12340 and LNAI 12341 constitutes the refereed proceedings of the 9th CCF Conference on Natural Language Processing and Chinese Computing, NLPCC 2020, held in Zhengzhou, China, in October 2020. The 70 full papers, 30 poster papers and 14 workshop papers presented were carefully reviewed and selected from 320 submissions. They are organized in the following areas: Conversational Bot/QA; Fundamentals of NLP; Knowledge Base, Graphs and Semantic Web; Machine Learning for NLP; Machine Translation and Multilinguality; NLP Applications; Social Media and Network; Text Mining; and Trending Topics.
Multimedia technology and enhanced learning ; 2nd EAI International conference, ICMTEL 2020, Leicester, UK, April 10-11, 2020, Proceedings, Part II
This two-volume book constitutes the refereed proceedings of the Second International Conference on Multimedia Technology and Enhanced Learning, ICMTEL 2020, held in Leicester, United Kingdom, in April 2020. Due to the COVID-19 pandemic all papers were presented in YouTubeLive. The 83 revised full papers have been selected from 158 submissions. They describe new learning technologies which range from smart school, smart class and smart learning at home and which have been developed from new technologies such as machine learning, multimedia and Internet of Things.
Multimedia Technology and Enhanced Learning ; 2nd EAI International Conference, ICMTEL 2020, Leicester, UK, April 10-11, 2020, Proceedings, Part I
This two-volume book constitutes the refereed proceedings of the Second International Conference on Multimedia Technology and Enhanced Learning, ICMTEL 2020, held in Leicester, United Kingdom, in April 2020. Due to the COVID-19 pandemic all papers were presented in YouTubeLive. The 83 revised full papers have been selected from 158 submissions. They describe new learning technologies which range from smart school, smart class and smart learning at home and which have been developed from new technologies such as machine learning, multimedia and Internet of Things.
Molecular Genetic Pathology
Molecular Genetic Pathology presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology.
Models and methods for management science
Introduces systems science as an entry point to present a basic introduction to research models and methods in management science (operation research). This textbook selects the classic quantitative models and methods as well as rich cases and detailed examples, which are suitable for students with a certain management and economics knowledge for further study, and helps to develop the abilities of using the basic models in real life
Mobile Edge Computing
It offers comprehensive, self-contained knowledge on Mobile Edge Computing (MEC), which is a very promising technology for achieving intelligence in the next-generation wireless communications and computing networks. The book starts with the basic concepts, key techniques and network architectures of MEC. Then, we present the wide applications of MEC, including edge caching, 6G networks, Internet of Vehicles, and UAVs. In the last part, we present new opportunities when MEC meets blockchain, Artificial Intelligence, and distributed machine learning (e.g., federated learning). We also identify the emerging applications of MEC in pandemic, industrial Internet of Things and disaster management.
Mobile Ad-Hoc and sensor networks ; 3rd International Conference, MSN 2007 Beijing, China, December 12-14, 2007 Proceedings
This book constitutes the refereed proceedings of the Third International Conference on Mobile Ad-hoc and Sensor Networks, MSN 2007, held in Beijing, China, in December 2007.
Medical Biometrics ; 1st International Conference, ICMB 2008, Hong Kong, China, January 4-5, 2008, Proceedings
Medical biometrics primarily refers to the usage of beh- ioral and physiological characteristics of humans for medical diagnosis and body care. Thus the goal of medical biometrics is to explore solutions to the open problems in medicine using biometric measurements, technologies and systems.
Mechanics of Microelectronics
Written by the leading experts with both profound knowledge and rich practical experience in advanced mechanics and microelectronics industry, this book aims to provide the cutting edge knowledge and solutions for various mechanical related problems, in a systematic way. It contains essential and detailed information about the state-of-the-art theories, methodologies, the way of working and real case studies.
Inventory and Supply Chain Management with Forecast Updates
Inventory and Supply Chain Management with Forecast Updates is concerned with the problems of inventory and supply chain decision making with information updating over time. The models considered include inventory decisions with multiple sources and delivery modes, supply-contract design and evaluation, contracts with exercise price, volume-flexible contracts allowing for spot-market purchase decisions, and competitive supply chains. Real problems are formulated into tractable mathematical models, which allow for an analysis of various approaches, and provide insights for better supply chain management. The book provides a unified treatment of these models, presents a critique of the existing results, and points out potential research directions. Attention is focused on solutions – that is, inventory decisions prior and subsequent to information updates and the impact of the quality of information on these decisions.
Internet and network economics ; 4th International Workshop, WINE 2008, Shanghai, China, December 17-20, 2008. Proceedings
This book constitutes the refereed proceedings of the 4th International Workshop on Internet and Network Economics, WINE 2008, held in Shanghai, China, in December 2008.The 68 revised full papers presented together with 10 invited talks were carefully reviewed and selected from 126 submissions. The papers are organized in topical sections on market equilibrium, congestion games, information markets, nash equilibrium, network games, solution concepts, algorithms and optimization, mechanism design, equilibrium, online advertisement, sponsored search auctions, and voting problems.
International trade theory : Capital, knowledge, economic structure, money, and prices over time
The development of international trade theory has created a wide array of different theories, concepts and results. Economic students are trained to understand international interactions by severally incompatible theories one by one in the same course. In order to overcome incoherence among multiple theories, we need a general theoretical framework which enables us to account for the phenomena explained by the current theories in a unified manner to draw together all of the disparate branches of trade theory into a single organized system of knowledge. This book provides a powerful – but easy to operate - engine of analysis that sheds light not only on trade theory per se, but on many other dimensions that interact with trade, including inequality, saving propensities, education, research policy, and knowledge. The book starts with the traditional static trade theories. Then, it develops dynamic models with capital and knowledge under perfect competition and/or monopolistic competition.
Immune regulation and immunotherapy in autoimmune disease
Assembles the insights and experience of over twenty experts and thought leaders in the field of autoimmune disease and immunotherapy. These discussions represent some of the newest concepts in autoimmune mechanisms and an array of new treatments that would have been considered science fiction only two decades ago. This book provides a wide-ranging review of two main arenas of current research: that of autoimmune mechanisms of disease and that of the latest developments in immunotherapy, with an emphasis upon multiple sclerosis.
