Natural Products : Drug Discovery and Therapeutic Medicine
Although the natural product drug discovery programs of the large drug companies are now equaled by programs for the high throughput screening of synthetic compounds generated through combinatorial chemistry, natural compounds still hold great promise to overcome such problems as antibiotic resistance, the emergence of new diseases, the failure to conquer old diseases, and the toxicity of some contemporary medical products. In Natural Products: Drug Discovery and Therapeutic Medicine, a panel of recognized experts and leaders in the field discuss the past successes of natural products as medicines and review future possibilities arising from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discovery, to accessing microbial diversity, to investigating specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to exploiting specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
كتب مشابهة
Nutraceuticals in respiratory and pulmonary diseases
Explores nutraceuticals that have been found to be effective in managing and treating respiratory and pulmonary diseases. It explains nutritional supplements that function as adjuvants for respiratory health and which may be useful targets for developing innovative nutraceutical-active respiratory products. The book also discusses the role of vitamins, minerals, and functional foods in the prevention and treatment of respiratory illnesses such as asthma, bronchitis, airway constriction, chronic obstructive pulmonary disorder (COPD), etc. It also explores the potential role of various herbs and foods in the treatment of lung illnesses through the Ayurvedic practices. The effectiveness of various natural and dietary supplements as well as plant and animal-based nutritional supplements for respiratory health are also considered.
Nutraceuticals and obesity strategies for weight management
his comprehensive volume explores the role that nutraceuticals can play in addressing obesity, shedding light on their potential as tools to promote sustainable weight management strategies as well as addressing associated health risks. Delving into the intricate interplay between nutrition, health, and obesity, the book provides a compelling account that illustrates how nutraceutical interventions can be incorporated into holistic obesity management strategies. It begins with an account of the mechanisms by which nutraceuticals function before featuring chapters on their efficacy and safety, how they can be integrated with other therapeutic interventions, and how they can be tailored for individuals with comorbidities. Offering a global perspective on the issue, there is also coverage of the various regulatory contexts in which nutraceuticals are sold and used.
Nutraceutical fruits : Overview and disease prevention
While nutritional supplements have enormous advantages, food ingredients such as fruits and vegetables can play a significant preventative and therapeutic role in our daily lives. Fruits are found to have anti-inflammatory, antibacterial, antifungal, and chemopreventive properties that can boost health, as well as prevent diseases. This new book explores the use of fruits as nutraceuticals for alternative treatment, as well as for disease prevention. It looks at how nutraceutical fruits can be used to prevent and manage a range of diseases that include mental illness, cancer, respiratory and lung diseases, cardiovascular diseases, liver disease, inflammatory bowel diseases, sleep disorders, etc. The book also looks at the roles of nutraceutical fruits in the metabolic syndrome and provides information regarding the safety and toxicity of neutraceutical fruits.
Next generation probiotics from novel drugs to future therapeutics
Provides a comprehensive and cutting-edge exploration of probiotics as powerful therapeutic agents. With the rapid advancements in the field, this book offers a deep dive into how probiotics are evolving beyond traditional uses, addressing complex health conditions and diseases in modern medicine. By combining the latest scientific research with practical applications, this book equips researchers, clinicians, and healthcare professionals with the knowledge needed to incorporate probiotics into clinical practice and future therapeutic strategies.
