الصفحة 7
الصفحة 7
Cannabinoids as Therapeutics
this volume concentrates on the diseases, the physiological effects and therapeutic use of cannabinoids. The volume editor Prof. Mechoulam was the first who isolated the prime active constituent (THC, Tetrahydrocannabiol) of marijuana. He published extensively on the pharmacological activities of cannabinoids. The volume is of interest to researchers and clinicians from pharmacology, neuroscience, and medicinal research
Cancer and Pregnancy
This book is written by experts with clinical expertise on diagnosis, treatment, and follow-up of women with cancer during pregnancy. It provides a comprehensive review of data and an overview of psychological, ethical, and social aspects.
Calcium Signalling and Disease : Molecular Pathology of Calcium
This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy.Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease).
Brilliant light in life and material sciences
This book aim to create a synchrotron radiation facility, CANDLE, as an international laboratory for advanced research in life and material sciences. About 50 researchers from NATO, partner countries and Armenia gathered at Yerevan to discuss modern trends in developments of advanced light sources with high spectral brilliance and applications in basic and applied research in a wide range of fields. Research with high brilliant photon beams are used, for example for practical applications in pharmacy, electronics and nanotechnology. Such practical relevance promoted the design and construction of now more than 50 such facilities worldwide. Overview and specialized talks on the status and highlights of newly constructed light sources (ALBA, SPEAR3, European XFEL Facility, Siberian Synchrotron Radiation Center, CANDLE), on instrumentation and development of experimental techniques, and frontier research in life and material sciences using synchrotron radiation have been presented.
Bone Resorption
Bone Resorption, the second volume in the series Topics in Bone Biology, deals with the osteoclast, the bone-resorbing cell, its origins, its enzymes, the regulation of osteoclast activity, and structural aspects of bone resorption. Diseases involving osteoclast function are discussed from the genetic viewpoint in two chapters that span transgenic mouse models to human pathology. Another chapter treats diseases of osteoclast function. Because osteoporosis may be considered a disease in which the bone resorption rate exceeds formation, a separate chapter deals with current and potential therapeutic approaches to this widespread disease that affects both men and women. Bone metastases and an analysis of the central role of the osteoclast in this condition are treated in the concluding chapter.
Bone remodeling and osseointegration of implants
Provides an insight into the latest advances in bone fracture healing and remodeling algorithm and their incorporation into patient-specific finite element models and the use of machine learning and artificial intelligence to predict the bone regeneration and osseointegration process with a certain degree of accuracy. It also examines the applications of numerical models to simulate the fracture healing process, which may prove to be advantageous in determining the optimal mechanical-based treatment or reconstruction after an accident or illness.
Bone Morphogenetic Proteins : From Local to Systemic Therapeutics
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.
Bone Marrow Derived Progenitors
The ability of stem cells to acquire different desired phenotypes has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. Each chapter has been written by an accomplished expert in the field, making this a hugely valuable resource for anyone looking for an up-to-the-minute assessment of current practice in adult bone marrow-derived cell therapy.
Bone Management in Dental Implantology
This book describes all methods of bone management currently employed within the field of dental implantology, with the aim of equipping oral surgeons and other practitioners with a sound practical understanding of bone augmentation. Readers will find clear guidance on diagnosis and treatment planning and helpful discussion of the basic principles of bone augmentation.
Bone disorders
• Bone is the specialized type of connective tissue that has extracellular matrix containing calcium salts. • As bone is a connective tissue, it consists of cells and matrix. • Mineralized extracellular matrix provides hardness to bones. • Bone is a living tissue that shows dynamic structural changes in response to physical stress and hormonal changes. • In addition to support and protection of vital organs, bones act as a storehouse for calcium and phosphates. • Bone also performs hematopoietic function (production of blood cells).
Bone densitometry in growing patients
Bone Densitometry in Growing Patients is the first resource available for expert opinion on the use of dual energy x-ray absorptiometry (DXA) for evaluating bone density in children and adolescents. Written by internationally recognized pediatric bone researchers and clinicians, this volume is unique in its specific attention to the myriad challenges of measuring and evaluating bone density in the pediatric patient. There is sufficient technical detail presented in this volume to enable the establishment of a pediatric DXA center or the proper utilization of DXA scan information in current clinical practice.
Bone densitometry for technologists
Radiologic technologists, nurse practitioners, physician assistants, and dedicated densitometry technologists can find new guidelines for bone density testing, new therapies for osteoporosis, and new treatment guidelines for osteoporosis, as well as new chapters on pediatric densitometry body composition assessments, and the use of skeletal morphometry in diagnosis and fracture risk prediction. The twelve appendices have also been updated to reflect the most current information available, including contacts for densitometry equipment manufacturers and organizations, guidelines for bone density testing and CPT codes, definitions of terms, and new conversion equations.
Bone augmentation in implant dentistry : A step-by-step guide to predictable alveolar ridge and sinus grafting
Implant dentistry has evolved tremendously over the past three decades and is rapidly progressing as new materials and protocols become available each year. With the number of advancements made in digitally based media and marketing, it is imperative that the clinician is able to separate new trends from evidence-based protocols to make sound and predictable choices for the ultimate benefit of patients. This textbook presents cases from the author's 35-year practice to show the successes and failures of various treatment approaches and protocols. Early chapters discuss the relevant biomaterials and instruments utilized for bone augmentation protocols, including barrier membranes, bone grafting materials, and growth factors. Surgical chapters dedicated to extraction socket management, alveolar ridge augmentation, and sinus grafting follow, each chapter detailing specific indications and patient selection criteria as well as step-by-step surgical procedures, aspects of postoperative treatment, and complications. The final chapter focuses on full-arch reconstruction using fully guided immediate reconstruction protocols. The author's teaching institute is credited with preparing some of the world's best clinicians, and this book will pave the way for countless more.
Bone augmentation by anatomical region : Techniques and decision-making
It's a unique, evidence-based guide focusing on each specific anatomical region – anterior maxilla, posterior maxilla, anterior mandible, and posterior mandible – in order to emphasize the correct implemented procedures needed to successfully perform oral osseous reconstruction.
Bone and Osteoarthritis
Bone and Osteoarthritis places emphasis on the molecular and cellular events that lead to osteoarthritis, stressing the role of subchondral bone, which distinguishes this from other books on the disease.
Bone and Cartilage Engineering
Bone and Cartilage Engineering presents the theory and practice of cell-based regeneration of skeletal defects. Much of the focus is on the importance of the cell biological and biomaterial aspects for engineering a clinically relevant device. The basic key techniques for optimal engineering outcomes including cell and organ culture, biomaterial development, and bioreactor use are described in detail and highlighted by multiple figures.
Bone : Biology, harvesting, and grafting for dental implants
Dental implant placement often requires bone grafting to ensure sufficient bony support for the implants being placed. Depending on the biologic conditions of the patient, including the level of bone atrophy and the status of the remaining teeth in the mouth, more adjunctive procedures like bone harvesting or sinus grafting may be required. This book covers it all, from the biology of bone and how dental implants work within that framework to the many procedures for harvesting bone and using it to augment sites for implant placement. The different types of bone grafts and membranes are discussed as well as procedures to preserve the alveolar ridge following tooth extraction.
Bisphosphonates in medical practice : Actions - side effects - indications - strategies
Clinical osteology is now an independent specialty which nevertheless encompasses all branches of medicine and effects each and every one of us: Bone is Every Body´s Business: This book has been designed as an up to date manual to deal with the currently recognized indications for bisphosphonates, to outline situations and conditions for prevention of skeletal disorders, and to provide practical guidelines for treatment. It is intended for doctors who seek precise information on bisphosphonates in medical practice to enable them to treat patients with disorders of bone or better still to avoid their occurrence .
Biomineralization II : Mineralization Using Synthetic Polymers and Templates
In nature, biological organisms produce mineralized tissues such as bone, teeth, diatoms, and shells. Biomineralization is the sophisticated process of production of these inorganic minerals by living organisms. Construction of organic–inorganic hybrid materials with controlled mineralization analogous to those produced by nature has recently received much attention because it can aid in understanding the mechanisms of the biomineralization process and development of biomimetic materials processing. The biomineralization processes use aqueous solutions at temperatures below 100 ◦C and no toxic intermediates are produced in these systems. This series presents critical reviews of the present position and future trends in modern chemical research. The short and concise reports on chemistry are each written by world renowned experts. This series is still valid and useful after 5 or 10 years.
Biomineralization I : Crystallization and Self-Organization Process
The five chapters of Biomineralization, volume 1, provide a bridge between the mineralogy and the organic substrates that enable the mineral formation by organisms in nature and under laboratory conditions. The book is a most useful reference for all concerned with biomineralization and biogenic minerals.In nature, biological organisms produce mineralized tissues such as bone, teeth, diatoms, and shells. Biomineralization is the sophisticated process of production of these inorganic minerals by living organisms. Construction of organic–inorganic hybrid materials with controlled mineralization analogous to those produced by nature has recently received much attention because it can aid in understanding the mechanisms of the biomineralization process and development of biomimetic materials processing.
