Bone Morphogenetic Proteins : From Local to Systemic Therapeutics
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.
كتب مشابهة
Data Technology in Materials Modelling
This book discusses advances in semantic interoperability for materials modelling, aiming at integrating data obtained from different methods and sources into common frameworks, and facilitating the development of platforms where simulation services in computational molecular engineering can be provided as well as coupled and linked to each other in a standardized and reliable way.
Comprehensive utilization of magnesium slag by pidgeon process
This book introduces the harmless handling/recycling of magnesium slag , the process of magnesium silicothermic reduction (Pidgeon process)which the slag was produced, and . the magnesium resources, layout of the industry of the world. Examples and experimental data in this book are from the author group’s research programs, as well as the rencent researches in China. The book could provide precious reference to scientists and engineers in the field of recycling and environment friendly use of the industrial solid wastes. It could also be used for researchers and students who are interested in relevant field.
Adhesive Bonding of Aircraft Composite Structures: Non-destructive Testing and Quality Assurance Concepts
This book is under a CC BY 4.0 license. It presents the results of the ComBoNDT European project, which aimed at the development of more secure, time- and cost-saving extended non-destructive inspection tools for carbon fiber reinforced plastics, adhered surfaces and bonded joints. The book reports the optimal use of composite materials to allow weight savings, reduction in fuel consumptions, savings during production and higher cost efficiency for ground operations.
Austenitic TRIP/TWIP steels and steel-zirconia composites : Design of tough, transformation-strengthened composites and structures
This book presents a collection of the most up-to-date research results in the field of steel development with a focus on pioneering alloy concepts that result in previously unattainable materials properties.
