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الصفحة 14
Natures Versatile Engine : Insect Flight Muscle Inside and Out
Integrates knowledge from various disciplines that study muscle function, from single molecule biophysics to flight aerodynamics. This work features information on advances in muscle research, from the molecular to the organismal. It focuses on Drosophila melanogaster, and other species of flying insects are also covered.
Nature-Based Solutions to Climate Change Adaptation in Urban Areas : Linkages between Science, Policy and Practice
This book is open access under a CC BY 4.0 license.This book brings together research findings and experiences from science, policy and practice to highlight and debate the importance of nature-based solutions to climate change adaptation in urban areas. Emphasis is given to the potential of nature-based approaches to create multiple-benefits for society
Nature-Based Flood Risk Management on Private Land : Disciplinary Perspectives on a Multidisciplinary Challenge
This book addresses the various disciplinary aspects of nature-based solutions in flood risk management on private land. In recent decades, water management has been moving towards nature-based solutions. These are assumed to be much more multi-purpose than traditional “grey infrastructures” and seem to be regarded as a panacea for many environmental issues. At the same time, such measures require more – and mostly privately owned – land and more diverse stakeholder involvement than traditional (grey) engineering approaches. They also present challenges related to different disciplines. Nature-based solutions for flood risk management not only require technical expertise, but also call for interdisciplinary insights from land-use planning, economics, property rights, sociology, landscape planning, ecology, hydrology, agriculture and other disciplines to address the challenges of implementing them. Ultimately, nature-based flood risk management is a multi-disciplinary endeavor.
Nature, Value, Duty : Life on Earth with Holmes Rolston, III
"Nature Value and Duty: Life on Earth with Holmes Rolston, III" is a collection of contemporary writings on the work of Holmes Rolston, III. The authors contributing to this volume are a mixture of senior scholars in environmental ethics and new voices in philosophy and in literature. Together they provide an in depth evaluation of many of the topics discussed by Rolston. They probe the strengths and weaknesses of his work and suggest valuable correctives. Rolston himself, in a detailed reply to each of his critics at the end of the volume, reveals where some of these criticisms sting him the most and in the process provides one of the most detailed and articulate defenses of his position ever offered."
Natural Skincare Cosmetics
Aging skin is suffering of decrease pigment-containing cells and overproduction of melanin in the skin, also changes in the connective tissue reduce the skin's strength and elasticity. Over the last 20 years, clinical and laboratory studies have identified the benefits of an array of natural ingredients for skin care. A variety of skin care products exist in today’s marketplace. They fulfill a variety of functions by either acting directly on the skin (e.g., moisturizers) or being a cosmetically elegant vehicle for the delivery of specific active ingredients (e.g., sunscreens or antipruritic or antiacne medicaments). Certain ingredients used in cosmeceuticals may be claimed to be therapeutic for common skin diseases. These ingredients are regulated as over the counter (OTC) drug monographs for acne, dermatitis/psoriasis, skin protectant, topical analgesia and sunscreens, by the Food and Drug Administration (FDA)
Natural Products Targeting Clinically Relevant Enzymes
Covers the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
Natural products and human diseases : Pharmacology, molecular targets, and therapeutic benefits
Provides insight into the clinical and translational application of natural products in human diseases Details the impact of natural products on a molecular basis Describes the identification of biomarkers, therapeutic effects of phytochemicals, and and new targets
Natural Products : Drug Discovery and Therapeutic Medicine
Although the natural product drug discovery programs of the large drug companies are now equaled by programs for the high throughput screening of synthetic compounds generated through combinatorial chemistry, natural compounds still hold great promise to overcome such problems as antibiotic resistance, the emergence of new diseases, the failure to conquer old diseases, and the toxicity of some contemporary medical products. In Natural Products: Drug Discovery and Therapeutic Medicine, a panel of recognized experts and leaders in the field discuss the past successes of natural products as medicines and review future possibilities arising from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discovery, to accessing microbial diversity, to investigating specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to exploiting specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Natural product experiments in drug discovery
Explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.
Natural poisons and venoms: Plant toxins : Polyketides, phenylpropanoids and further compounds
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.
Natural poisons and venoms : Animal toxins
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.
Natural poisons and venom : Plant toxins : Terpenes and steroids
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.
Natural Oral Care in Dental Therapy
Because of increasing antibiotic resistance, stronger antibiotics are reserved for serious active infection, paving the way for a greater use of herbal antibiotics. This book helps dentists in implementing safe and effective natural medicine therapies to complement the current practice guidelines. Oral diseases continue to be a major health problem world-wide. Oral health is integral to general well-being and relates to the quality-of-life that extends beyond the functions of the craniofacial complex. The standard Western medicine has had only limited success in the prevention of periodontal disease and in the treatment of a variety of oral diseases.
Natural occurrence and biological activities of quinoline derivatives
Provides a comprehensive overview of quinoline derivatives, focusing on their chemical structure, biological activities, and therapeutic benefits. It delves into the natural sources of these derivatives, covering their isolation, characterization, and potential therapeutic applications, particularly in areas such as anti-cancer, anti-inflammatory, antimicrobial, and antimalarial activity. With its emphasis on providing valuable reference material, this book is an indispensable resource for researchers, educators, and professionals in the fields of chemistry, biology, pharmacology, and drug discovery.
Natural Language Processing and Information Systems ; Vol. 3999 ; 11th International Conference on Applications of Natural Language to Information Systems, NLDB 2006, Klagenfurt, Austria, May 31 - June 2, 2006, Proceedings
This book constitutes the refereed proceedings of the 11th International Conference on Applications of Natural Language to Information Systems, NLDB 2006, held in Klagenfurt, Austria in May/June 2006 as part of UNISCON 2006. The book presents 17 revised full papers and 5 revised short papers, organized in topical sections on concepts extraction and ontology, ontologies and task repository utilization, query processing, information retrieval and dialog processing, and NLP techniques.
Natural Language Processing and Information Systems ; Vol. 3513 ; 10th International Conference on Applications of Natural Language to Information Systems, NLDB 2005, Alicante, Spain, June 15-17, Proceedings
The development and convergence of computing, telecommunications and information systems has already led to a revolution in the way that we work, communicate with each other, buy goods and use services, and even in the way that we entertain and educate ourselves.The revolution continues, and one of its results is that large volumes of information will increasingly be held in a form which is more natural for users than the data presentation formats typical of computer systems of the past. Natural language processing (NLP) is crucial in solving these problems, and language technologies will make an indispensable contribution to the success of information systems. We hope that NLDB 2005 was a modest contribution to this goal. NLDB 2005 contributed to advancing the goals and the high international standing of these conferences, largely due to its Program Committee, composed of renowned researchers in the field of natural language processing and inf- mation system engineering. Papers were reviewed by three reviewers from the Program Committee. This clearly contributed to the significant number of - pers submitted (95). Twenty-nine were accepted as regular papers, while 18 were accepted as short papers.
Natural Language Processing – IJCNLP 2005 ; 2nd International Joint Conference, Jeju Island, Korea, October 11-13, 2005, Proceedings
The Theme of IJCNLP 2005: “NLP with Kimchee”, a Conference with a Unique Flavor Welcometo IJCNLP 2005,thesecondannualconferenceof theAsian Federation ofNaturalLanguageProcessing(AFNLP). Followingthesuccessofthe?rstc- ference held in the beautiful cityof Sanya,Hainan Island,China, in March2004, IJCNLP 2005 is held in yet another attractive Asian resort, namely Jeju Island in Korea, on October 11–13, 2005
Natural Disasters as Interactive Components of Global-Ecodynamics
This book opens a new approach to the study of global environmental changes having unfavourable character for mankind and other living systems. The main advantage of the book consists in the accumulation of knowledge from different sciences to parametrize the global ecodynamic process. Natural catastrophes are considered as an interactive element of global natural dynamics which are described by means of simulation models of global nature/society. The realization of this approach allows the integration within a complex structure of all international and national means of environmental monitoring and provides a tool for objective evaluation of the environmental quality. The main purpose of this book is to develop a universal information technology to estimate the state of environmental subsystems functioning under various climatic and anthropogenic conditions.
Natural Disasters and Extreme Events in Agriculture : Impacts and Mitigation
Agricultural production is highly dependent on weather, climate and water availability and is adversely affected by the weather and climate-related disasters. Droughts and natural disasters such as floods can result in crop failures, food insecurity, famine, loss of property and life, mass migration and negative national economic growth. It may not be possible to prevent the occurrence of these natural disasters, but the resultant disastrous effects can be reduced considerably through proper planning and effective preparation. Vulnerability associated with the hazards of natural disasters can be controlled to some extent by accurate and timely prediction and by taking counter-measures to reduce their impacts on agriculture. This book based on an expert meeting held in Beijing, China should be of interest to all organizations involved in disasters reduction and mitigation of extreme events.
Natural anti-depressant drugs
Mental health problem and neurological disorders are a serious public health concern globally with more than one billion sufferers worldwide. Depression, anxiety, stress, and other mental disorders, which are on the rise worldwide, are indications that pharmacological therapy can have serious adverse effects, which is why many patients prefer to use herbal products to treat these symptoms. Because pharmacotherapy of depression is a long-term process associated with the risk of numerous adverse drug effects, much attention is paid to alternative therapy methods, including phytopharmacotherapy, especially in treating mild or moderate depression.
