الصفحة 14
الصفحة 14
Natural Products : Drug Discovery and Therapeutic Medicine
Although the natural product drug discovery programs of the large drug companies are now equaled by programs for the high throughput screening of synthetic compounds generated through combinatorial chemistry, natural compounds still hold great promise to overcome such problems as antibiotic resistance, the emergence of new diseases, the failure to conquer old diseases, and the toxicity of some contemporary medical products. In Natural Products: Drug Discovery and Therapeutic Medicine, a panel of recognized experts and leaders in the field discuss the past successes of natural products as medicines and review future possibilities arising from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discovery, to accessing microbial diversity, to investigating specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to exploiting specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Natural product experiments in drug discovery
Explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.
Natural Polysaccharides in Drug Delivery and Biomedical Applications
Provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field.Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process.
Natural Oral Care in Dental Therapy
Because of increasing antibiotic resistance, stronger antibiotics are reserved for serious active infection, paving the way for a greater use of herbal antibiotics. This book helps dentists in implementing safe and effective natural medicine therapies to complement the current practice guidelines. Oral diseases continue to be a major health problem world-wide. Oral health is integral to general well-being and relates to the quality-of-life that extends beyond the functions of the craniofacial complex. The standard Western medicine has had only limited success in the prevention of periodontal disease and in the treatment of a variety of oral diseases.
Natural occurrence and biological activities of quinoline derivatives
Provides a comprehensive overview of quinoline derivatives, focusing on their chemical structure, biological activities, and therapeutic benefits. It delves into the natural sources of these derivatives, covering their isolation, characterization, and potential therapeutic applications, particularly in areas such as anti-cancer, anti-inflammatory, antimicrobial, and antimalarial activity. With its emphasis on providing valuable reference material, this book is an indispensable resource for researchers, educators, and professionals in the fields of chemistry, biology, pharmacology, and drug discovery.
Natural Language Processing and Information Systems ; Vol. 3513 ; 10th International Conference on Applications of Natural Language to Information Systems, NLDB 2005, Alicante, Spain, June 15-17, Proceedings
The development and convergence of computing, telecommunications and information systems has already led to a revolution in the way that we work, communicate with each other, buy goods and use services, and even in the way that we entertain and educate ourselves.The revolution continues, and one of its results is that large volumes of information will increasingly be held in a form which is more natural for users than the data presentation formats typical of computer systems of the past. Natural language processing (NLP) is crucial in solving these problems, and language technologies will make an indispensable contribution to the success of information systems. We hope that NLDB 2005 was a modest contribution to this goal. NLDB 2005 contributed to advancing the goals and the high international standing of these conferences, largely due to its Program Committee, composed of renowned researchers in the field of natural language processing and inf- mation system engineering. Papers were reviewed by three reviewers from the Program Committee. This clearly contributed to the significant number of - pers submitted (95). Twenty-nine were accepted as regular papers, while 18 were accepted as short papers.
Natural language and information systems ; 13th International Conference on Applications of Natural Language to Information Systems, NLDB 2008 London, UK, June 24-27, 2008 Proceedings
This volume contains the papers presented at NLDB 2008, the 13th Inter- tional Conference on Natural Language and Information Systems, held June 25-27,2008.It also containssome of the best researchproposalsas submitted to the NLDB2008 doctoral symposium heldonJune24,2008.Theprogrammealso includes three invited talks covering the main perspectives of the application of naturallanguageto informationsystems: the wayhumansprocess, communicate and understand natural language, what are the implications and challenges - wardssemanticsearchfor the new Webgeneration, how naturallanguageapplies to the well-established database way of querying as a means to unlock data and information for end users.
Natural Fullerenes and Related Structures of Elemental Carbon
This book provides an up-to-date summary of the state of knowledge on natural fullerenes occurrences and the laboratory techniques used to determine their presence at low concentration in rock samples. It demonstrates that natural fullerenes exist and should be searched for in places not yet considered such as carbon-containing deep-seated crustal rocks.Natural Fullerenes and Related Structures of Elemental Carbon is written for professional astronomers, meteoriticists, earth and planetary scientists, biologists and chemists interested in carbon and hydrocarbon vapor condensation. It is an invaluable resource for practicing research scientists and science teachers in Earth and Planetary Science, Astronomy and Carbon Science.
Natural Compounds as Drugs ; Vol. II
This book highlights new trends and aspects in natural products research. It discusses the biodiversity-driven approaches which are now of eminent importance in natural products research, addressing the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.
Natural Compounds as Drugs ; Vol. I
This book highlights new trends and aspects in natural products research. It discusses the biodiversity-driven approaches which are now of eminent importance in natural products research, addressing the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.
Natriuretic Peptides : The Hormones of the Heart
The rapid knowledge in the field of neuro-humoral regulation of cardiovascular pathophysiology is changing the picture of current diagnosis and treatment of cardiac patients. The emerging conceptual revolutionary idea is that heart acts not as a pump, merely, but as a "gland", that is as a regulator of circulatory homeostasis and salt-water balance. Cardiovascular pathophysiology has to be written, indeed, on this basis: this physiology textbook gives an up-to-date description of the complexity and novelty of actual knowledge, with all its potential clinical implications.
National Tax Policy in Europe : To Be or Not to Be?
The book is dedicated to the question of how much room for national tax policy Member States of the European Union will find necessary and possible to maintain in the future. It focuses on the possibilities Member States have and the constraints they face, such as the need to enhance competitiveness and attractiveness to inward foreign direct investment, to finance social programmes and the limitations imposed by European and International Law. The research question is looked at from economic as well as from legal points of view. This comprehensive approach and the answers given will be of interest to scholars and policy makers alike and may guide the path for future tax developments in Europe.
National Systems of Innovation in Comparison : Structure and Performance Indicators for Knowledge Societies
The book documents major elements of the joint work of eight leading German institutes, elaborated in the context of a regular annual report on Germany's technological performance. It provides much more than the pure compilation of quantitative indicators for international benchmarking, but gives support to an appropriate interpretation of the referring results and suggests relevant conclusions for innovation policy. A special focus is on Germany; so the book also aims at non-German readers interested in specific features of the German innovation system.
National Institute of Allergy and Infectious Diseases, NIH ; Vol.1 : Frontiers in Research
National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research contains presentations given at the 2006 NIAID Research Conference held in Opatija, Croatia which brought internationally known researchers from the United States and Central and Eastern Europe to focus together on shared interests in microbiology, infectious disease, HIV/AIDS, and basic and clinical immunology. Some of the topics covered include emerging and re-emerging infections, the development of infectious disease prophylactics and therapeutics, drug resistance, and various topics in immunomodulation, autoimmunity, infections and immunity, and the development of vaccines.Extensive and in-depth, National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research is a valuable, comprehensive guide to the state of research today.
NASH and Nutritional Therapy
This collection of research and clinical findings on nonalcoholic steatchepatitis (NASH) and nutritional therapy contains significant new findings in several fields . As NASH frequently causes liver cirrhosis, the nutritional aspects of its treatment are discussed . Other areas covered include nonalcoholic fatty liver, the role of leptin in the pathogenesis of NASH, restricted diets and exercise therapy, mammalian targets of the peptide rapamycin, and genetic factors influencing the development of NASH.
Narrowing the Achievement Gap : Strategies for Educating Latino, Black, and Asian Students
This volume is an important and impressive collection of scholarship that addresses one of the more intractable education problems of our times--ensuring that ALL children receive a quality education." -- Gloria Ladson-Billings, Kellner Family Professor in Urban Education University of Wisconsin at Madison, and 2005-2006 President of AERA "A major contribution to the field, the in-depth analyses provided by the chapter authors should be of substantial appeal to a wide audience because of its interdisciplinary approach and orientation to theory, research, and practice." -- Stanley Sue, Distinguished Professor of Psychology and Asian American Studies University of California at Davis "In considering the broad problems and in recommending solutions, the book provides breadth, concision, and unique organization." -- Edmund W. Gordon, John M.
Narrow Gap Semiconductors 2007 ; Proceedings of the 13th International Conference, 8-12 July, 2007, Guildford, UK
Narrow gap semiconductors have provided an exciting field of research and show a number of extreme physical and material characteristics. They are the established material systems for infrared detectors and emitters, and with new developments in the technology these materials are emerging as a viable route to high speed, low power electronics. New kinds of narrow gap semiconductor, such as graphene and other composite nanocrystals, are also providing renewed interest in the underlying physics.
Nanotechnology in Catalysis 3
This book is the third volume of Nanotechnology in Catalysis. Although has been only 2 years since the Volumes 1 and 2 were published, many new contributions and breakthroughs have been made by researchers all over the world, showing the dynamic of nanotechnology in catalysis area. The topics in the book are the most up-to-date information on the forefront of nanotechnology development in catalysis field. They include the new concept and applications of nanotechnology for catalysis, the preparation and characterization of nanoparticle and nanostructure catalysts, and the examples of the superior activity and selectivity achieved by using such nanocatalysts. This book provides an in-depth understanding of how nanotechnology can affect the future generation of catalyst development.
Nanotechnology for Environmental Remediation
The newly discovered advanced oxidation technology using nanoscale zero-valent iron, which is reported in this book, could be widely used to treat pesticides, herbicides, and industrial chemicals as well as to purify contaminated water for domestic use. In addition, it can contribute to advancing science and technology and providing valuable information to all readers - researchers, scientists, engineers, and students - in this field for their further research and studies.
Nanotechnology applied To pharmaceutical technology
Focuses on devising innovative nanopharmaceutical products and solutions to treat such diseases as cancer, infections, eye diseases, and in tackling multi-drug resistance threats. Nanotechnology Applied to Pharmaceutical Technology consists of four sections that include coverage of biosynthesis of nanoparticles, nano-material based formulations and toxicity, and safety issues.
