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Cooperative Information Agents XI ; Matthias Klusch, Koen V. Hindriks, Mike P. Papazoglou, Leon Sterling
In today’s world of ubiquitously connected heterogeneous information systems and computing devices, the intelligent coordination and provision of relevant added-value information at any time, anywhere is of key importance to a va- ety of applications. This challenge is envisioned to be coped with by means of appropriate intelligent and cooperative information agents. An information agent is a computational software entity that has access to one or multiple heterogeneous and geographically dispersed data and infor- tion sources. It pro-actively searches for and maintains information on behalf of its human users, or other agents preferably just in time. In other words, it is managing and overcoming the di?culties associated with information overload in open, pervasive information and service landscapes. Each component of a modern cooperative information system is represented by an appropriate intelligent information agent capable of resolving system and semantic heterogeneities in a given context on demand. Cooperative infor- tion agents are supposed to accomplish both individual and shared joint goals depending on the actual user preferences in line with given or deduced limits of time, budget and resources available.
Conceptual Modelling in Information Systems Engineering
Conceptual modeling has always been one of the cornerstones for information systems engineering as it describes the general knowledge of the system in the so-called conceptual schema.It contiant data modeling, goal-oriented modeling, agent-oriented modeling, and process-oriented modeling. Overall, the contributions reflect the most important developments and application areas of conceptual modeling in recent years, and they also pinpoint trends in conceptual modeling for the next decade.
Computing and Combinatorics ; 13th Annual International Conference, COCOON 2007, Banff, Canada, July 16-19, 2007, Proceedings
The Book covers most aspects of theoretical computer scienceand combinatorics related to computing.It exploring research, development, and novel applications of computing and combinatorics.
Computational Science -- ICCS 2005 ; Vol. 3515 ; 5th International Conference, Atlanta, GA, USA, May 22-25, 2005, Proceedings, Part I
This book constitutes the refereed proceedings of the Fifth International Conference on Computational Science (ICCS 2005) held in Atlanta, Georgia, USA, 2005, Computational science is rapidly maturing as a mainstream discipline. It is central to an ever-expanding variety of ?elds in which computational methods and tools enable new discoveries with greater accuracy and speed. The primary objectives of this conference were to discuss problems and solutions in allareas,toidentifynewissues,toshapefuturedirectionsofresearch,andtohelp users apply various advanced computational techniques. The event highlighted recent developments in algorithms, computational kernels, next generation c- puting systems, tools, advanced numerical methods, data-driven systems, and emerging application ?elds, such as complex systems, ?nance, bioinformatics, computational aspects of wireless and mobile networks, graphics, and hybrid computation.
Computational Life Sciences ; Vol. 4216 ; 2nd International Symposium, CompLife 2006, Cambridge, UK, September 27-29, 2006, Proceedings
This book constitutes the refereed proceedings of the Second International Symposium on Computational Life Sciences, CompLife 2006. The papers are organized in topical sections on genomics, data mining, molecular simulation, molecular informatics, systems biology, biological networks/metabolism, and computational neuroscience.
Computational Life Sciences ; Vol. 3695 ; 1st International Symposium, CompLife 2005, Konstanz, Germany, September 25-27, 2005, Proceedings
This book constitutes the refereed proceedings of the First International Symposium on Computational Life Sciences, CompLife 2005, held in Konstanz, Germany in September 2005. The integration of knowledge in the life sciences is continuing apace with ev- increasingimportancebeing placedoncomputer-basedmethodsofdata capture, analysis, and knowledge representation. Today, our many di?erent sciences are providing us with a sea of information: it is the handling of this in?ux that is becoming a key discovery and regulatory question. The solutions to these problems will result in advancements to all of the involved sciences and will be highly in?uential both in the selection of the areas scientists seek to investigate and also on their success. For this to happen, it is crucial to establish an open and lively exchange between computer scientists, biologists, and chemists. To encourage precisely this type of exchange, crossing the borders of the sciences, we organized the 1st Symposium on Computational Life Science in Konstanz, Germany(September 25 27,2005).
Computational intelligence and security ; Vol. 3801 ; International Conference, CIS 2005, Xi'an, China, December 15-19, 2005, Proceedings, Part I
The two volume set LNAI 3801 and LNAI 3802 constitute the refereed proceedings of the annual International Conference on Computational Intelligence and Security, CIS 2005, held in Xi'an, China, in December 2005. The 338 revised papers presented - 254 regular and 84 extended papers - were carefully reviewed and selected from over 1800 submissions. The first volume is organized in topical sections on learning and fuzzy systems, evolutionary computation, intelligent agents and systems, intelligent information retrieval, support vector machines, swarm intelligence, data mining, pattern recognition, and applications.
Large-Scale Scientific Computing ; 6th International Conference, LSSC 2007, Sozopol, Bulgaria, June 5-9, 2007. Revised Papers
The 6th International Conference on Large-Scale Scienti?c Computations (LSSC 2007) was held in Sozopol, Bulgaria, June 5–9, 2007. The conference was organized by the Institute for Parallel Processing at the Bulgarian Academy of Sciences in cooperation with SIAM (Society for Industrial and Applied Ma- ematics). Partial support was also provided from project BIS-21++ funded by the European Commission in FP6 INCO via grant 016639/2005. The conference was devoted to the 60th anniversary of Richard E. Professor Ewing is internati- ally well known with his contributions in applied mathematics, mathematical modeling, and large-scale scientific computations.
Knowledge Discovery and Emergent Complexity in Bioinformatics ; 1st International Workshop, KDECB 2006, Ghent, Belgium, May 10, 2006, Revised Selected Papers
Contains selected and revised papers of the International Symposium on Knowledge Discovery and Emergent Complexity in Bioinformatics (KDECB 2006), held at the University of Ghent, Belgium, May 10, 2006.
Comparative genomics ; Vol.4205 ; RECOMB 2006 International Workshop, RECOMB-CG 2006, Montreal, Canada, September 24-26, 2006, Proceedings
The papers address a broad variety of aspects and components of the field of comparative genomics, ranging from new quantitative discoveries about genome structure and process to theorems on the complexity of computational problems inspired by genome comparison.
Comparative genomics ; Vol. 3388 : RECOMB 2004 International Workshop, RCG 2004, Bertinoro, Italy, October 16-19, 2004, Revised Selected Papers
This papers investigates the problem of conservation of combinatorial structures in genome rearrangement scenarios. We give a characterization of a class of scenarios that conserve all common intervals, called commuting scenarios, and a characterization of permutations for which commuting scenarios exist. We show that measuring conservation of common intervals can be useful tool in assessing the quality of rearrangement scenarios, by investigating in detail three specific scenarios involving the mouse, rat and human X chromosomes.
Building an Enterprise Architecture Practice : Tools, Tips, Best Practices, Ready-to-Use Insights
This book clearly describes how to establish an architecture practice that delivers value for an organization. The authors demonstrate a wealth of experience and a deep understanding of the multifaceted nature of this challenging task and they provide sound advice on how to avoid the many pitfalls that may be encountered along the way. Building an Enterprise Architecture Practice provides practical advice on how to develop your enterprise architecture practice.
Bio-informatique moléculaire : Une approche algorithmique = Molecular bioinformatics : An algorithmic approach
Deals with genetic maps, from the problem of sequence comparison and alignment, including DNA chips and genomic rearrangement. It thus covers a wide variety of topics relating to algorithmic and combinatorial processing of questions arising from molecular bioinformatics and biotechnology.
Bioinformatics
In this textbook present mathematical models in bioinformatics and they describe the biological problems that inspire the computer science tools used to handle the enormous data sets involved. The first part of the book covers the mathematical and computational methods, while the practical applications are presented in the second part. The mathematical presentation is descriptive and avoids unnecessary formalism, and yet remains clear and precise. Emphasis is laid on motivation through biological problems and cross applications. Each of the four chapters in the first part is accompanied by exercises and problems to support an understanding of the techniques presented. Each of the six chapters of the second part is devoted to some specific application domain: sequence alignment, molecular phylogenetics and coalescence theory, genomics, proteomics, RNA, and DNA microarrays. Each chapter concludes with a problems and projects section, to deepen the reader's understanding and to allow for the design of derived methods. Many of the projects involve publicly available software and/or Web-based bioinformatics depositories. Finally, the book closes with a thorough bibliography, reaching from classic research results to very recent findings, providing many pointers for future research.Overall, this volume is ideally suited for a senior undergraduate or graduate course on bioinformatics, with a strong focus on its mathematical and computer science background.
Anatomy ontologies for bioinformatics : Principles and practice
This book provides a timely and first-of-its-kind collection of contributed chapters on anatomy ontologies. It is interdisciplinary in its approach, bringing together relevant expertise from computing and biomedical studies, and covering both theoretical and applied aspects, with an emphasis on newer work relevant to the emerging Semantic Web.
Algorithms in Bioinformatics ; Vol.4175 : 6th International Workshop, WABI 2006, Zurich, Switzerland, September 11-13, 2006, Proceedings
This book constitutes the refereed proceedings of the 6th International Workshop on Algorithms in Bioinformatics, WABI 2006, held in Zurich, Switzerland in September 2006 in the course of the ALGO 2006 conference meetings. The 36 revised full papers presented were carefully reviewed and selected from 100 submissions. All current issues of algorithms in bioinformatics are addressed, ranging from mathematical tools to experimental studies of approximation algorithms and reports on significant computational analyses. Numerous biological problems are dealt with, including genetic mapping, sequence alignment and sequence analysis, phylogeny, comparative genomics, and protein structure. For the first time also machine-learning approaches along with combinatorial optimization are covered.
Algorithms in Bioinformatics ; Vol. 3692 ; 5th international workshop, WABI 2005, Mallorca, Spain, October 3-6, 2005, Proceedings
this book present the proceedings of the 5th Workshop on Algorithmsin Bioinformatics (WABI 2005) which took place in Spain, 2005. The Workshop on Algorithms in Bioinformatics highlights research workspecifically developed to address algorithmic problems in biosequence analysis. The emphasis is therefore on statistical and probabilistic algorithms that addressimportant problems in the field of molecular and structural biology. the workshop aims to present recent research results, includingsignificant work in progress, and to identify and explore directions of futureresearch.Original research papers (including significant work in progress) or state-of-the-art surveys were solicited on all aspects of algorithms in bioinformatics,including, but not limited to: exact and approximate algorithms for genomics,genetics, sequence analysis, gene and signal recognition, alignment, molecularevolution, phylogenetics, structure determination or prediction, gene expressionand gene networks, proteomics, functional genomics, and drug design.
Algorithms in Bioinformatics ; 7th International Workshop, WABI 2007, Philadelphia, PA, USA, September 8-9, 2007, Proceedings
All current issues of algorithms in bioinformatics are addressed, ranging from mathematical tools to experimental studies of approximation algorithms and reports on significant computational analyses. Numerous biological problems are dealt with, including genetic mapping, sequence alignment and sequence analysis, phylogeny, comparative genomics, and protein structure. Furthermore the papers feature high-performance computing approaches to computationally hard learning and optimization problems in bioinformatics and cover methods, software and dataset repositories for development and testing of such algorithms and their underlying models.
Algorithms in Bioinformatics : Theory and Implementation
Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results
Algorithmic Aspects of Bioinformatics
Advances in bioinformatics and systems biology require improved computational methods for analyzing data, while progress in molecular biology is in turn influencing the development of computer science methods. This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. After introducing the basics of molecular biology and algorithmics, Part I explains string algorithms and alignments; Part II details the field of physical mapping and DNA sequencing; and Part III examines the application of algorithmics to the analysis of biological data. Exciting application examples include predicting the spatial structure of proteins, and computing haplotypes from genotype data. This book describes topics in detail and presents formal models in a mathematically precise, yet intuitive manner, with many figures and chapter summaries, detailed derivations, and examples. It is well suited as an introduction into the field of bioinformatics, and will benefit students and lecturers in bioinformatics and algorithmics, while also offering practitioners an update on current research topics.
