الصفحة 1
الصفحة 1
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New Frontiers in Angiogenesis

New Frontiers in Angiogenesis starts with a comprehensive overview of the field and continues with topics that have been minimally explored. The topics deal with dynamics of vasculogenesis using imaging techniques, bone marrow-derived endothelial cell precursors as potential therapeutic tools, regulation of post-angiogenic vessel regression, vascular mimicry, design and construction of artificial vessels, bioengineering of angiogenesis, and lymphangiogenesis recapitulating angiogenesis in health and disease states. Each chapter is written by leading experts of the subjects. It is hoped that this volume will challenge all of us interested in the field of angiogenesis and cardiovascular biology, in particular those in academia and industries, to think "outside the box" and explore angiogenesis from a fresh angle. It is hoped that New Frontiers in Angiogenesis is thought provoking and serve as a road map for discovering new findings to help betterments of human health.

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New Business Models for the Reuse of Secondary Resources from WEEEs : The FENIX Project

This book summarizes research being pursued within the FENIX project, funded by the EU community under the H2020 programme, the goal of which is to design a new product service paradigm able to promote innovative business models, to open added value to the vessels and to create new market segments. It experiments and validates its approach on three new concepts of added-value specialized vessels able to run requested services for several maritime sectors in the most effective, efficient, economic valuable and eco-friendly way. The three vessels share the same lean design methodology, IoT tools and HPC simulation strategy: a lean fact-based design model approach, which combines real operative data at sea with lean methodology, to support the development and implementation of the vessel concepts; IT customized tools to enable the acquisition, processing and usage of on board and local weather data, through an IoT platform, to provide business services to different stakeholders; HPC simulation, providing a virtual towing tank environment, for early vessel design improvement and testing. The book demonstrates that an integrated LCC analysis and LCC strategy to guarantee sustainability to vessels concepts and the proper environmental attention inside the maritime industry.

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MRI of the Heart and Vessels

In recent years magnetic resonance imaging (MRI) has enriched the technological potential available for the characterization of cardiovascular pathologies, adding substantial advantages to other non-invasive techniques. This technique, which is intrinsically digital and has reduced operator dependency, allows the performance of image analysis in a quantitative and reproducible manner. In virtue of its added diagnostic value and inherent refinements that allow construction of two- and three-dimensional images, MRI is gaining a primary role in the histopathological and physiopathological understanding of a large number of pathologies concerning the heart and vessels. This text is addressed both to MRI operators seeking specific technical information and to clinicians who wish to have a better understanding of the diagnostic and management advantages that MRI can offer.

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Mortality and Maldevelopment : Part I : Congenital cardiovascular malformations

The most frequent of them all are the many types of malformations of the cardiovascular system, the heart and its blood vessels.Study of these conditions during the twentieth century took many forms, revolving about examination and analysis of their causes, genetic, nongenetic, and complex. To aid in unraveling the complexities of this causation, various influences on their frequency are considered, among them social conditions, maternal health, birthweight, newborn maturity. And of course the known and possible environmental bases of their occurrence are fully described.

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Microcirculation in Cardiovascular Diseases

This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention.

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Homocysteine

Homocysteine is a non-proteinogenic α-amino acid. It is a homologue of the amino acid cysteine, differing by an additional methylene bridge (-CH2-). It is biosynthesized from methionine by the removal of its terminal methyl group. In the body, Homocysteine (HCY) can be recycled into methionine or converted into cysteine with the aid of certain B-vitamins. A high level of Homocysteine in the blood (hyperhomocysteinemia) makes a person more prone to endothelial cell injury, which leads to inflammation in the blood vessels, which in turn may lead to atherogenesis, which can result in ischemic injury. Therefore, hyperhomocysteinemia is a possible risk factor for coronary artery disease (CAD). Coronary artery disease occurs when an atherosclerotic plaque blocks blood flow to the coronary arteries, which supply the heart with oxygenated blood.

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Handbook of vascular biometrics

This handbook provides the first comprehensive overview of biometrics exploiting the shape of human blood vessels for biometric recognition, i.e. vascular biometrics, including finger vein recognition, hand/palm vein recognition, retina recognition, and sclera recognition.

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General ultrasound in the critically ill

General ultrasound in the critically ill describes a bedside tool destined for use by the intensivist and any physician involved in emergencies. It specifically deals with findings of immediate clinical relevance throughout the body. New emergency applications of ultrasound in the abdomen, the vessels, the head and the heart are considered. The major topic, the lung, is extensively discussed. Interventional ultrasound forms part of nearly every chapter. Flow charts simplify daily concerns: acute dyspnea, shock, unexplained fever, etc. The strong points and pitfalls of ultrasound are reviewed. Technical notes are mingled with general considerations. Benefiting from the extensive experience of an intensivist intimately familiar with ultrasound, this book accurately answers most daily problems arising in the critically ill. it offers not only an exhaustive atlas but also a permanent aid to the therapeutic decision. All in all, General ultrasound in the critically ill provides a key for practicing a kind of visual medicine. Since 1990 Daniel Lichtenstein has been an intensivist in a medical ICU which already occupied a pioneering place in echocardiography. He has from the beginning devoted his efforts to the development of general ultrasound. He regularly publishes studies on lung ultrasound, his main topic, in the international literature.

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Free Energy and Self-Interacting Particles

This book examines a system of parabolic-elliptic partial differential eq- tions proposed in mathematical biology, statistical mechanics, and chemical kinetics. In the context of biology, this system of equations describes the chemotactic feature of cellular slime molds and also the capillary formation of blood vessels in angiogenesis. There are several methods to derive this system. One is the biased random walk of the individual, and another is the reinforced random walk of one particle modelled on the cellular automaton. In the context of statistical mechanics or chemical kinetics, this system of equations describes the motion of a mean field of many particles, interacting under the gravitational inner force or the chemical reaction

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Ecology of Baltic Coastal Waters

The Baltic Sea is one of the most investigated water bodies in the world. For decades, the many highly industrialised nations around the Baltic have financed basic and applied investigations, as well as the building and development of research stations and vessels. After World War II, research in the Baltic Proper was intensified and investi- tions became much more international. The main goals of such investigations were analysis of the eutrophication and pollution of the Baltic Sea, and development of mitigating strategies (e.g. the HELCOM-Program). In contrast, research into the coastal zones was carried out mainly under national sovereignty by individual governments due to differing political regimes. Consequently, there was a lack of international collaboration and publications regarding these regions. This changed following the collapse of the former socialist governments. Nevertheless, research activities in the coastal regions still lag behind those in the Baltic Proper. A general description is further hampered by the great variety of coastal water ecosystems. The aim of this book is to overcome this lack by presenting the important Baltic coastal zones in the form of “ecological case studies”. In this way the book rep- sents an important supplement to literature concerning the Baltic Proper.

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Diseases of the chest, heart and vascular system 2025-2028 : Diagnostic imaging

Offers an essential overview of chest, heart and vascular system imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text.

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Diseases of the Chest, Breast, Heart and Vessels 2019-2022 : Diagnostic and Interventional Imaging

This book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions.

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Dermatopathology

The book describes the principles of histopathologic patterns in selected acquired skin diseases, together with short clinical descriptions and case reports. The underlying, or possible underlying, mechanisms are elucidated, and controversial concepts are discussed. To facilitate the understanding of underlying mechanisms, the first chapters of the book comprise summaries of basic histology of lymphatics and blood vessels, relevant parts of general pathology, immunology, and molecular cell biology.

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Maritime Archaeology : Australian Approaches

Subject areas discussed in this book include shipwrecks and abandoned vessels, The application of National and State legislation and management regimes to these underwater cultural heritage sites is also highlighted, together with the important role of avocational divers and training programs in raising the profile of underwater and maritime heritage sites.The book includes a comprehensive bibliography of work conducted both in Australia and by Australian maritime archaeologists in the Asia-Pacific region. This book will be of interest to students and practitioners of maritime and historical archaeology and cultural heritage managers throughout the world .

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Magnetic resonance angiography : techniques, indications and practical applications

The advent of contrast-enhanced MRA in the early to mid 1990s revolutionized the clinical approach to vascular imaging: an accurate non-invasive imaging modality, not requiring ionizing radiation or potentially nephrotoxic iodinated contrast media, was able to compete with the more hazardous and invasive catheter angiography. Today, MRA is a safe, easy-to-perform procedure routinely used in most imaging centers, and the continued development of faster, more powerful magnets and more effective contrast agents is increasingly helping to overcome many of the early limitations of the technique.

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Compulsory Insurance and Compensation for Bunker Oil Pollution Damage

Oil tankers are not the only vessels that have caused oil pollution at sea. Numerous spills in the past have been of heavy fuel oil from non-tankers. However, the international liability and compensation regime covered only oil pollution damage caused by oil tankers. There was thus a need to bring the law on marine oil pollution responsive to oil pollution damage caused by non-tankers. In March 2001, the International Convention on Civil Liability for Bunker Oil Pollution Damage was adopted following a diplomatic conference at the International Maritime Organization. Though this convention has not yet come into force, its various aspects should already be considered as they will surely affect the maritime industry as a whole and the non-tanker sector, in particular. This book provides a timely and comprehensive study on the concept of compulsory insurance, its main purpose of ensuring compensation and its interrelations with other features such as the rule of strict liability and the limitation of liability under the convention.

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Clinical Cardiac MRI

MRI has become the preferred noninvasive imaging modality for the heart and great vessels. The substantial technological progress achieved in recent years has provided the user with state of the art MRI systems, but their optimal use can be limited by restricted awareness of the potential patient benefit and the necessity for teaching. This extensively illustrated volume, has been specifically compiled to meet these needs. Essential theoretical background information is provided, and imaging acquisition and potential pitfalls are considered in detail. Most importantly, structured guidelines are provided on the interpretation of clinical data in the wide range of cardiac pathology that can be encountered. Throughout, the emphasis is on the implementation of cardiac MRI in clinical practice.

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Cardiovascular Regeneration Therapies Using Tissue Engineering Approaches

The cardiovascular system transports oxygen and nutrients to all parts of the body; therefore, any impediment to this system through, for example, a circulatory disorder, represents a serious threat to organs, tissues, and cells. Obstructive diseases of vessels with a diameter of more than 1 mm can be treated by conventional surgical and interventional approaches; however, blockages in small vessels with a diameter of less than 1 mm cannot be treated by conventional methods. As a consequence, therapeutic ang- genesis and vasculogenesis for the treatment of ischemic diseases have been widely studied in the last decade. These methods may contribute to the re­ pair of intractable cardiovascular diseases with a main vascular involvement in the body's smallest vessels. In this book, Hikaru Matsuda and I have tried to summarize recent Japanese developments in the field of cardiovascular regeneration therapies using tissue engineering.

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Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

Covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others. presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that affect small (to medium) sized blood vessels. They include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg–Strauss syndrome).

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Antidiabetic medicinal plants and herbal treatments

Diabetes is a chronic condition associated with metabolic disorder. Persons suffering from diabetes have shown accelerated levels of blood sugar which often harms the heart, blood vessels, eyes, kidneys, and nerves. Over the past few decades, the prevalence of diabetes has been progressively increasing. Synthetic drugs are used to treat diabetic patients to help control the disorder, but it is shown that numerous medicinal plants and herbal drugs are widely used in several traditional systems of medicine to prevent and treat diabetes. They are reported to produce beneficial effects in combating diabetes and alleviating diabetes-related complications. These plants contain phtyonutrients and phytoconstituents demonstrating protective or disease preventive properties. In many developing countries, herbal drugs are recommended by traditional practitioners for diabetes treatment because the use of synthetic drugs is not affordable.

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