الصفحة 1
الصفحة 1
Office Andrology
The investigation and management of male infertility can be a formidable diagnostic challenge to family physicians, urologists, and reproductive specialists alike. In Office Andrology, noted clinical physicians and scientists have joined forces to create a comprehensive resource guide to current diagnostic and treatment options for a broad spectrum of clinical issues relevant to male infertility disorders. Topics covered range from basic sperm biology and male reproductive endocrinology, to immunology, specialized sperm testing, and the genetic background to male infertility. Although emphasis is on the investigation, diagnostic testing, and management of the infertile male, controversial medical and surgical treatment options are also fully discussed. For the reproductive specialist, the text thoughtfully reviews such timely issues as gender selection, human immunodeficiency virus-discordance couples, and posthumous reproduction. Other topics of interest include laboratory accreditation, vasectomy reversal, ethical and legal considerations of donor insemination, optimizing success in a donor insemination program, and strategic therapies for ejaculatory disorders and erectile dysfunction in infertile men.
Ocular Transporters in Ophthalmic Diseases and Drug Delivery
This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In Ocular Transporters in Ophthalmic Diseases and Drug Delivery, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium, and the transport of nutrients across the retinal pigment epithelium. It also provides an in-depth look at how mutations or dysfunction of specific transporters can contribute to various disorders in the eye, including blindness, and provides readers with potential targets and strategies to allow safe passage of therapeutic drugs into the eye.
Oceans and Health: Pathogens in the Marine Environment
The importance of combating infectious diseases has received international attention, p- viding the opportunity for a multidisciplinary approach that combines medicine with other scientist candtechnological capabilities,notably information technology,nanotechnology,and biotechnology. In fact, it has been predicted that the future will bring a merging of these te- nologies with the cognitive and behavioral sciences.. The connection between infectious diseases and the oceans provides a paradigm for this perspective. A stark global context indisputably frames all human health issues in the twenty century: the world wide movement of people and goods. Throughout the past half century, international travel has skyrocketed; there are more than 500 million international arrivals per year. The greatest increase has taken place since the mid-1990s. The world has become integrated and global; consequently, the notion that it is possible to successfully eradicate a disease from the face of the planet has become simplistic. Infectious disease is a moving target and climate shifts will affect any disease that has an environmentally sensitive stage or vector.
Oceano fertilità : Psicologia della comunicazione nell'era della fecondazione assistita = Fertility Ocean : The psychology of communication in the age of assisted reproduction
Cosa si prova a non poter avere un figlio? Quanto è difficile comunicare alla coppia una diagnosi di sterilità? Come affrontare il 70% dei fallimenti delle tecniche di PMA? Come una legge puo' incidere sul futuro di un embrione? Il testo, nato dalla fusione multidisciplinare medica, psicologica e sociologica, vuole riflettere su queste domande e accompagnare il lettore in una nuova forma mentis sulle criticità nella fecondazione assistita.
Obstetrics in Family Medicine : A Practical Guide
The key points for each topic are summarized in tabular form for quick reference, and diagnostic flow charts illuminate all aspects of the decision-making process. Expert advice based on years of experience is also presented concerning physical and ultrasound examinations, laboratory tests, drug toxicities, and screening techniques.
Obstetric medicine : A problem-based approach
This book is a collection of exam questions and case studies which illustrates both common and more unusual problems in obstetric medicine. Using a problem–based approach to both teach and test knowledge, it incorporates many different approaches to obstetric medicine, in Q & A format. The ‘Extended Matched Questions’ section covers the breadth of theoretical knowledge. The ‘Short Answers / Data Interpretation’ section requires a systematic approach to a clinical problem. Most of the case reports are based on real cases and all are accompanied by a brief literature review to further broaden the learning experience.
Object-oriented metrics in practice : Using software metrics to characterize, Evaluate, and Improve the design of object-oriented systems
The combination of theoretically sound results and practically tested procedures and solution paths makes this book an ideal companion for professional software architects, developers and quality engineers. The pattern-oriented description of disharmonies offers easy access to detecting shortcomings and applying solution strategies. "This well-written book is an important piece of work that takes the seemingly forgotten art of object-oriented metrics to the next level in terms of relevance and usefulness."
Object detection with deep learning models : Principles and applications
Discusses recent advances in object detection and recognition using deep learning methods, which have achieved great success in the field of computer vision and image processing. It provides a systematic and methodical overview of the latest developments in deep learning theory and its applications to computer vision, illustrating them using key topics, including object detection, face analysis, 3D object recognition, and image retrieval / A structured overview of deep learning in object detection / A diversified collection of applications of object detection using deep neural networks / Emphasize agriculture and remote sensing domains / Exclusive discussion on moving object detection
Obesity and Diabetes
The increasing prevalence of diabetes and obesity in western societies today makes these two diseases the leading epidemics of the 21st century. Closely linked with the development of serious complications, including cardiovascular disease and several malignancies, the morbidity and mortality associated with obesity and diabetes will continue to escalate as the population ages and becomes more sedentary. In Obesity and Diabetes, international experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity.
Obesity and Cancer
This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development.
Nuucleic acids in medicinal chemistry and chemical biology : Drug development and clinical applications
Delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers. The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field
Nutritional psychiatry
Provides a comprehensive overview of nutritional psychiatry, elucidating its theoretical foundations, the biological mechanisms linking diet to mental health (including inflammation, oxidative stress, disrupted energy metabolism the gut–brain axis and other implicated pathways), and the current evidence base for dietary impacts on major psychiatric disorders such as depression, anxiety, schizophrenia, bipolar disorder, and ADHD.
Nutrition, diet and healthy aging
Over the last 100 years, the numerous advances in science, the improved sanitary conditions and a decline in poverty have led to an increase in life expectancy. As a result, in the coming years, the number of over-65s will triple, and the over-80s will be the fastest growing portion of the population. However, an increased lifespan is associated with an increase in chronic diseases, such as cardiovascular disease, diabetes, cancer, sarcopenia, and degenerative disorders. Therefore, ideally, increased lifespan should be associated to a better healthspan, which is the period one individual is living in good health
Nutrition and Oral Health
Explores in depth the relationships between nutrition and oral health across all age groups. Discusses the latest knowledge on the consequences of poor diet for tooth loss and progression of oral diseases . Explains the importance of a disease-free and functional dentition for nutritional well-being
Nutrition and Gastrointestinal Disease
Nutritional support of people with gastrointestinal impairment is critical to treatment and ultimately successful management. As such, gastroenterologists should be experts in nutrition and knowledgeable about the affects of nutrition on disease management. Nutritional and Gastrointestinal Disease fulfills that need, serving as a hands-on, practical reference in nutrition support for the clinical gastroenterologist and other clinicians with similar interests. The volume offers expert nutritional knowledge and management ideas as well as methodology for combating problems such as short bowel syndrome, inflammatory bowel disease, celiac disease and obesity. Renowned authorities also investigate nutrition’s influence on such issues as liver failure and acute pancreatitis. While gastroenterology training programs around the world remain deficient in their nutrition curriculum, Nutritional and Gastrointestinal Disease provides a comprehensive and groundbreaking support for clinical gastroenterologists.
Nursing Care of the Pediatric Neurosurgery Patient
Nursing Care of the Pediatric Neurosurgery Patient serves as a detailed reference for all nurses caring for children with neurosurgical problems. Staff nurses (and student nurses) working in clinics, PICU, pediatrics, operating rooms, post-anesthesia care units, emergency department and radiology will benefit from the information presented in this book. The explanations of pathophysiology, anatomy, radiodiagnostic testing and treatment options for each neurosurgical diagnosis will help them to understand the rationale behind the nursing care. Presenting symptoms and findings on neurological examination and history will enable nurses to identify normal signs. Each chapter includes information on patient and family education and will give helpful guidelines.
Numerical Methods in Finance
The use of mathematical models and numerical techniques in finance is a growing practice, and an increasing number of applied mathematicians are working on applications in finance and business. This book presents some exciting developments arising from the combination of mathematics, numerical analysis, and finance. It covers a wide range of topics, from portfolio management and asset pricing, to performance, risk, debt and real option evaluation. It also presents applications of a variety of cutting edge approaches and techniques, including robust control, min-max optimisation, Bessel processes, stochastic viability, variational inequalities, and Monte-Carlo test techniques. The book also presents surveys of models and approaches in specific areas in finance, such as corporate debt valuation and portfolio selection
Numerical Mathematics and Advanced Applications ; Proceedings of ENUMATH 2005 the 6th European Conference on Numerical Mathematics and Advanced Applications, Santiago de Compostela, Spain, July 2005
This book include applications such as atmosphere and ocean, water pollution, electromagnetism, interface problems, waves, finance, heat transfer, unbounded domains, numerical linear algebra, convection-diffusion, fluid-structure, plates, solids, hyperbolic equations, multiphase flow, Navier-Stokes, singular perturbation problems, non linear PDE, control, parabolic equations, as well as methodologies such as a posteriori error estimates, discontinuous Galerkin methods, multiscale methods, optimization, adaptive methods, domain decomposition techniques, exponential integrators, hp-finite elements, level set methods, fractional step methods, penalty procedures, and finite volumes. The book gives an extensive overview of the most recent research in scientific computing, providing to the reader the latest developments concerning the mathematical issues and the applications of this active field of science.
Nucleic Acids and Proteins in Soil
With millions of different bacterial species living in soil, the microbial community is extremely complex, varying at very small scales. Microbe-driven functions are essential for most processes in soil. Thus, a better understanding of this microbial diversity will be invaluable for the management of the various soil functions. Nucleic Acids and Proteins in Soil combines traditional approaches in soil microbiology and biochemistry with the latest techniques in molecular microbial ecology. Included are methods to analyse the presence and importance of nucleic acids and proteins both inside and outside microbial cells, the horizontal gene transfer which drives bacterial diversity, as well as soil proteomes. Further chapters describe techniques such as PCR, fingerprinting, the challenging use of gene arrays for structural and functional analysis, stable isotope probing to identify in situ metabolic functions, and the use of marker and reporter genes in soil microbial ecology.
Nuclear Risks in Central Asia
Insights into uranium production sites and nuclear explosion testing sites in Former Soviet Union countries Unique information on contamination of NORM and other radionuclides in Central Asia and Caucasus area Highlighting the need of radiation protection in areas contaminated by uranium exploitation in Central Asia and Caucasus area
