الصفحة 1
الصفحة 1
Oncology : An Evidence-Based Approach
Reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.
Numerical Simulation of Mechatronic Sensors and Actuators
The second edition of this book fully preserves the character of the first edition to combine the detailed physical modeling of mechatronic systems and their precise numerical simulation using the Finite Element (FE) method. Most of the text and general appearance of the previous edition were retained, while the coverage was extended and the presentation improved. A large part of the book describes the application of the developed numerical calculation schemes to industrial problems, e.g.: analysis and optimization of electrodynamic loudspeakers. In these parts, new computational methods are included, and last but not least, this new edition contains a new chapter on computational aeroacoustics to study the complex phenomenon of flow induced noise.
Novel Optical Resolution Technologies
After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capable of resolving the surface as wellas the insid estructure of crystalsat the atomiclevel while newhigh-performance computing resourcesafford thecapability of modeling the complexlarge-scale alignments necessary to simulatecrystallizationinrealsystems. Asaresult, the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization process.The vastpotential ofcrystallizationasan- portant feld ofscience isfar beyondthesimple technologyofpharmaceutical industries during the 20th century.
Nonlinear Structural Engineering : With Unique Theories and Methods to Solve Effectively Complex Nonlinear Problems
This book is aiming to concentrate on the nonlinear static and dynamic analysis of structures and structural components that are widely used in everyday engineering applications. It approaches a nonlinear problem by mathematically converting it into an exact equivalent pseudolinear one, in contrast to commonly used approaches which are based on linear concepts. The new concepts, theories and methods introduced in this book, simplify a great deal the solution of the complex nonlinear problems, and also allow for the correct usage of the powerful existing linear methods of analysis.
Nonlinear finite element analysis of composite and reinforced concrete beams
Nonlinear Finite Element Analysis of Composite and Reinforced Concrete Beams presents advanced methods and techniques for the analysis of composite and FRP reinforced concrete beams. The title introduces detailed numerical modeling methods and the modeling of the structural behavior of composite beams, including critical interfacial bond-slip behavior. It covers a new family of composite beam elements developed by the authors. Other sections cover nonlinear finite element analysis procedures and the numerical modeling techniques used in commercial finite element software that will be of particular interest to engineers and researchers executing numerical simulations.
Non-Equilibrium Phase Transitions ; Vol. I : Absorbing Phase Transitions
This book describes two main classes of non-equilibrium phase-transitions: (a) static and dynamics of transitions into an absorbing state, and (b) dynamical scaling in far-from-equilibrium relaxation behaviour and ageing. The first volume begins with an introductory chapter which recalls the main concepts of phase-transitions, set for the convenience of the reader in an equilibrium context. The extension to non-equilibrium systems is made by using directed percolation as the main paradigm of absorbing phase transitions and in view of the richness of the known results an entire chapter is devoted to it, including a discussion of recent experimental results. Scaling theories and a large set of both numerical and analytical methods for the study of non-equilibrium phase transitions are thoroughly discussed.
Next Generation Design and Verification Methodologies for Distributed Embedded Control Systems ; Proceedings of the GM R&D Workshop, Bangalore, India, January 2007
This volume is the proceedings of the workshop “Next Generation Design and Verification Methodologies for Distributed Embedded Control Systems” organised by General Motors R&D, India Science Lab. The workshop was held on January 5-6 2007 at the NIAS auditorium, IISc campus, Bangalore, India. This workshop is the first of its kind to be organised by an automotive major to bring together the leaders in the field of embedded systems development to present state-of-the-art work, and to discuss future strategies for addressing the increasing complexity of embedded control systems. The workshop consisted of invited talks given by leading experts and researchers from academic and industrial organizations.
Neuroendocrine cells and peptidergic innervation in human and rat prostrate
Introduction The prostate causes a signi?cant number of medical problems in the adult male, and the lower urinary tract symptoms are accepted as an unavoidable consequence of male aging. Most of these symptoms are mainly due to clinical benign prostatic hyperplasia (BPH), which is the most frequent benign tumor in the male, in- pendent of race or culture. On the other hand, cancer of the prostate shows an increasing incidence, being the second leading cause of death in men, after lung cancer.
Multiscale processes in the earth’s magnetosphere : From interball to cluster ; Proceedings of the NATO ARW on Multiscale Processes in the Earth's Magnetosphere: From Interball to Cluster, Prague, Czech Republic from 9 to 12 September 2003
The past forty years of space research have seen a substantial improvement in our understanding of the Earth’s magnetosphere and its coupling with the solar wind and interplanetary magnetic ?eld (IMF). The magnetospheric str- ture has been mapped and major processes determining this structure have been de?ned. However, the picture obtained is too often static. We know how the magnetosphere forms via the interaction of the solar wind and IMF with the Earth’s magnetic ?eld. We can describe the steady state for various upstream conditions but do not really understand the dynamic processes leading from one state to another. The main dif?culty is that the magnetosphere is a comp- cated system with many time constants ranging from fractions of a second to days and the system rarely attains a steady state. Two decades ago, it became clear that further progress would require multi-point measurements. Since then, two multi-spacecraft missions have been launched — INTERBALL in 1995/96 and CLUSTER II in 2000. The objectives of these missions d- fered but were complementary: While CLUSTER is adapted to meso-scale processes, INTERBALL observed larger spatial and temporal scales. However, the number of papers taking advantage of both missions simul- neously is rather small.
Multirate Statistical Signal Processing
This book introduces a statistical theory for extracting information from signals that have di?erent sampling rates. This new theory generalizes the conventional (deterministic) theory of multirate systems beyond many of its constraints.Furthermore,itallowsfortheformulationofseveralnewproblems such as spectrum estimation, time-delay estimation and sensor fusion in the realm of multirate signal processing. I have arrived at the theory presented here by integrating concepts from diverse areas such as information theory, inverse problems and theory of - equalities. The process of merging a variety of concepts of di?erent origin results in both merits and shortcomings. The former include the fresh and - di?erentiated view of an amateur, providing scope of application. The latter include a lack of in-depth experience in each of the original ?elds. Granted, this may lead to gaps in continuity, however it goes without saying that a complete theory can seldom be achieved by one person and in a short time.
Multifunctional Barriers for Flexible Structure : Textile, Leather and Paper
The intent of this book is to give a complete overview of the present state of the art of flexible barrier materials such as textile, paper and leather, including methods for barrier evaluation. It will be of interest to readers in industries, consumers, and members of the scientific community. The scope of the field is clearly delineated here for the first time, and it deals with a number of specific topics such as barrier to fire, antibacterial properties, resistance to waves (electrostatic, electromagnetic, acoustics), anti-odor, etc. combined with characterization techniques as well as material nanotechnology.
Multi-Arm Cooperating Robots : Dynamics and Control
This book will be useful to a wide audience of engineers, ranging from undergraduate and graduate students, new and advanced academic researchers, to practitioners (mechanical and electrical engineers, computer and system scientists). It is intended for readers whose work involves manufacturing, industrial, robotics, automation, computer and control engineering, and who wish to find out about this important new technology and its potential advantages for control engineering applications.
Morphometrics with R
The R language and environment offers a single platform to perform a multitude of analyses from the acquisition of data to the production of static and interactive graphs. This offers an ideal environment to analyze shape variation and shape change. This open-source language is accessible for novices and for experienced users. Adopting R gives the user and developer several advantages for performing morphometrics: evolvability, adaptability, interactivity, a single and comprehensive platform, possibility of interfacing with other languages and software, custom analyses, and graphs. The book explains how to use R for morphometrics and provides a series of examples of codes and displays covering approaches ranging from traditional morphometrics to modern statistical shape analysis such as the analysis of landmark data, Thin Plate Splines, and Fourier analysis of outlines.
Modeling Semantic Web Services : The Web Service Modeling Language
In this book, Jos de Bruijn and his coauthors lay the foundations for understanding the requirements that shape the description of the various aspects related to Semantic Web services, such as the static background knowledge in the form of ontologies, the functional description of the service, and the behavioral description of the service. They introduce the Web Service Modeling Language (WSML), which provides means for describing the functionality and behavior of Web services, as well as the underlying business knowledge, in the form of ontologies, with a conceptual grounding in the Web Service Modeling Ontology.
Modeling of Biological Materials
This interdisciplinary collection of surveys highlights the central role played by the mathematical modeling of mechanical properties having an effect on the biology, chemistry, and physics of living matter. One of the main goals of the book is to present—in a single, self-contained resource—topics that are widely scattered across the literature in a variety of journals having mutually nonintersecting communities of readers, such as applied mathematicians, engineers, biologists, and physicians. Readers coming from diverse backgrounds are provided with basic modeling ideas and tools to address important problems in the medical and health sciences. Presented are appropriate models as well as their implementation through numerical and computer simulations, which may lead to potential technological innovations useful in medicine.
Model Checking Software ; 15th International SPIN Workshop, Los Angeles, CA, USA, August 10-12, 2008 Proceedings
This book constitutes the refereed proceedings of the 15th International SPIN workshop on Model Checking Software, SPIN 2008, held in Los Angeles, CA, USA, in August 2008.The 17 revised full papers presented together with 1 tool paper and 4 invited talks were carefully reviewed and selected from 41 submissions. The main focus of the workshop series is software systems, including models and programs. The papers cover theoretical and algorithmic foundations as well as tools for software model checking and foster interactions and exchanges of ideas with related areas in software engineering, such as static analysis, dynamic analysis, and testing.
Micrometastasis
Distant metastases are the main cause of cancer-related death. The onset of the metastatic process can now be assessed in cancer patients by the use of immunocytochemical and molecular methods that allow the identification of disseminated carcinoma cells in regional lymph nodes, peripheral blood or distant organs. There is increasing evidence that the detection and characterization of tumor cells present in bone marrow or peripheral blood can provide clinically important information. In this book, leading experts in the area of micrometastasis research provide an overview that summarizes the current state of research on micrometastatic disease in patients with solid tumors. In each chapter, the technical aspect as well as clinical relevance of micrometastasis detection is discussed. The book addresses basic researchers as well as clinicians involved in the treatment of cancer patients.
Micro-, Meso- and Macro-Connectomics of the Brain
Highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Metastasis of Prostate Cancer
Without metastasis, prostate cancer would be both tolerable and treatable. The high incidence of indolent and organ confined disease is testament to this sweeping generalisation. Equally, if molecular markers of metastatic spread can be identified, then the choice of treatment for many patients would be easier and more radical, even curative. However, should prevention and treatment of the primary tumors prove difficult or impossible.
Meshless Methods in Solid Mechanics
The main objective of this book is to provide a textbook for graduate courses on the computational analysis of continuum and solid mechanics based on meshless (also known as mesh free) methods. It can also be used as a reference book for engineers and scientists who are exploring the physical world through computer simulations. Emphasis of this book is given to the understanding of the physical and mathematical characteristics of the procedures of computational solid mechanics. It naturally brings the essence, advantages and challenging problems of meshless methods into the picture. The subjects in this book cover the fundamentals of continuum mechanics, the integral formulation methods of continuum problems, the basic concepts of finite element methods, and the methodologies, formulations, procedures, and applications of various meshless methods. It also provides general and detailed procedures of meshless analysis on elastostatics, elastodynamics, non-local continuum mechanics and plasticity with a large number of numerical examples. Some basic and important mathematical methods are included in the Appendixes. For the readers who want to gain knowledge through hands-on experience, the meshless programs for elastostatics and elastodynamics are also introduced in the book and included in the disc.
