الصفحة 1
الصفحة 1
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Oncology : An Evidence-Based Approach

Reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.

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Office Andrology

The investigation and management of male infertility can be a formidable diagnostic challenge to family physicians, urologists, and reproductive specialists alike. In Office Andrology, noted clinical physicians and scientists have joined forces to create a comprehensive resource guide to current diagnostic and treatment options for a broad spectrum of clinical issues relevant to male infertility disorders. Topics covered range from basic sperm biology and male reproductive endocrinology, to immunology, specialized sperm testing, and the genetic background to male infertility. Although emphasis is on the investigation, diagnostic testing, and management of the infertile male, controversial medical and surgical treatment options are also fully discussed. For the reproductive specialist, the text thoughtfully reviews such timely issues as gender selection, human immunodeficiency virus-discordance couples, and posthumous reproduction. Other topics of interest include laboratory accreditation, vasectomy reversal, ethical and legal considerations of donor insemination, optimizing success in a donor insemination program, and strategic therapies for ejaculatory disorders and erectile dysfunction in infertile men.

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Object-Oriented Technology. ECOOP 2007 Workshop Reader ; ECOOP 2007 Workshops, Berlin, Germany, July 30-31, 2007, Final Reports

Contains the reports from the workshopsheld at the 21st European Conference on Object-Oriented Programming - ECOOP 2007 - at Technische Universit] at Berlin. Nineteen workshops were heldin the courseofthis conference on July 30 and July 31, 2007, covering a large spectrum of hot research topics. As in previous editions of ECOOP, numerous scientists from academia and industry took the chance to present innovative and topical ideas in an environment ofering optimal conditions for exciting discussions and fruitful interactions. The Workshop Reader which contains the reports from the workshops has been a substantial part of the ECOOP conference for more than10 years

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Object-Oriented Technology ; ECOOP 2006 Workshop Reader ; ECOOP 2006 Workshops, Nantes, France, July 3-7, 2006, Final Reports

ECOOP Workshop Reader, a c- pendium of workshop reports pertaining to the ECOOP 2006 conference, held in Nantes during July 3–7, 2006. ECOOP 2006 hosted 19 high-quality research workshops covering a large spectrum of hot research topics. These workshops were chosen through a tight peer review process following a speci?c call for proposals.

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Object-Oriented Technology ; ECOOP 2001 Workshops, Panel, and Posters, Budapest, Hungary, June 18-22, 2001. Proceedings

For the ?fth time in its history, in cooperation with Springer-Verlag, the European C- ference on Object-Oriented Programming (ECOOP) conference series is glad to offer the object-oriented research community the ECOOP 2001 Workshop Reader, a c- pendium of workshop reports, panel transcripts, and poster abstracts pertaining to the ECOOP 2001 conference, held in Budapest from 18 to 22 June, 2001. ECOOP 2001 hosted 19 high-quality workshops covering a large spectrum of - search topics. The workshops attracted 460 participants on the ?rst two days of the conference. Originally 22 workshops were chosen from 26 proposals by a workshop selection committee, following a peer review process. Due to the overlaps in the areas of interest and the suggestions made by the committee six of the groups decided to merge their topicsintothreeworkshops.

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NSTAR 2007 ; Proceedings of The 11th Workshop on The Physics of Excited Nucleons, 5–8 September 2007, Bonn, Germany

The excitation spectrum of the nucleon offers insights into the non-perturbative regime of QCD. The NStar workshops are a series of meetings that bring together experimenters and theoreticians working on baryon resonances and related areas. This work covers the proceedings that constitute an archival record of the progress in the field.

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Novel mouse model for future autism research

Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures in the first 3 years of life. It is not a single disorder, and it is broadly considered to be a multi-factorial disorder resulting from genetic and non-genetic risk factors and their interaction. Genetic studies of ASD have identified mutations that interfere with typical neurodevelopment in utero through childhood. These complexes of genes have been involved in synaptogenesis and axon motility. Recent developments in neuroimaging studies have provided many important insights into the pathological changes that occur in the brain of patients with ASD in vivo. Especially, the role of amygdala, a major component of the limbic system and the affective loop of the cortico-striatothalamo-cortical circuit, in cognition and ASD has been proved in numerous neuropathological and neuroimaging studies.

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Non-viral Gene Therapy: Gene Design and Delivery

The development of gene medicine based on the concept of molecular therapy has opened new medical horizons. Among the many techniques in gene medicine, gene design and delivery are especially significant in clinical applications. This book presents state-of-the-art information on non-viral gene-delivery techniques, covering a broad spectrum of disciplines that include chemistry, molecular biology, cell biology, and pharmacokinetics

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Non-Surgical Control of Periodontal Diseases : A Comprehensive Handbook

Designed for practicing dental clinicians and students, which includes dental hygienists, general dentists, periodontists, and students of dental hygiene and dentistry who are responsible for treating patients with a broad spectrum of periodontal diseases.

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Noninvasive Imaging of Myocardial Ischemia

Non-invasive imaging plays a very important role in the assessment of patients investigated for coronary artery disease, providing valuable information for diagnosis and aiding management decisions. It covers a broad spectrum of investigations including radionuclide imaging, echocardiography, magnetic resonance imaging and computed tomography. Progress towards the most efficacious means of assessing a patient is relentless, with recent years seeing an important shift in emphasis from invasive to noninvasive techniques. This informative book compares the various modalities in a practical diagnostic environment. It thus provides a forum for fertile discussion, bringing the discussion of these various methodologies together in one reference for the first time. The narrative flow is unique and will ensure that all levels of medical practitioners with an interest in cardiac imaging will find this an unparalleled resource for use in guiding their practice.

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Nonequilibrium Carrier Dynamics in Semiconductors ; Proceedings of the 14th International Conference, July 25-29, 2005, Chicago, USA

International experts gather every two years at this established conference to discuss recent developments in theory and experiment in non-equilibrium transport phenomena. These developments have been the driving force behind the spectacular advances in semiconductor physics and devices over the last few decades. Originally known as "Hot Carriers in Semiconductors," the 14th conference in the series covered a wide spectrum of traditional topics dealing with non-equilibrium phenomena, ranging from quantum transport to optical phenomena in mesoscopic and nano-scale structures. Particular attention was given this time to emerging areas of this rapidly evolving field, with many sessions covering terahertz devices, high field transport in nitride semiconductors, spintronics, molecular electronics, and bioelectronics applications.

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New Dimensions of Business Reporting and XBRL

The authors of this book analyse the social and technical nature and role of XBRL in information supply chains and capital markets as well as the XBRL standard and taxonomies. They provide a critical view of XBRL from a research perspective, present different projects in the XBRL area and indicate future directions for XBRL research. Current research questions are taken up and discussed from different perspectives. From a technical point of view, the research spectrum encompasses the internal perspective up to the final user layer. Apart from these technical issues, there are also key socio-technical aspects which are vital to the understanding of XBRL use.

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New and Evolving Infections of the 21st Century

This new volume of the Emerging Infectious Diseases of the 21st Century Series, has complied a collection of chapters by leading authorities of the world on emerging & evolving infections that is a must read for anyone interested in this topic. The chapters by reknown experts have provided a wealth of up-date information, such as clinical spectrum of disease, epidemiology, pathogenesis, diagnosis, management, prevention and future research.

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Network-Aware Security for Group Communications

Network-Aware Security for Group Communications fills a growing need in the research community for a reference that describes the state-of-the-art in securing group communications in emerging networks and for future applications. The growth of multi-user services makes it essential that a complementary suite of security solutions are deployed in order to protect these services from a broad spectrum of security threats that are unique to group communications. This book is focused on tailoring security solutions to the underlying network architecture (such as the wireless cellular network, or ad hoc and sensor networks), or to targeted applications using methods tailored for that application (such as multimedia multicasts).

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Natural Products Targeting Clinically Relevant Enzymes

Covers the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.

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Nanoscale Assembly : Chemical Techniques

Recent advances have pushed the limits of lithography firmly into the sub-100 nm domain, with smallest feature sizes around 10 nm. However, compared to living organisms, devices fabricated using nanolithography are not nearly as complex, as they are essentially 2D and contain only a limited number of chemical elements. For centuries, Nature has been a major inspiration for science. First of all to learn how Life functions at cellular level, but increasingly, as a blueprint for designing non-natural devices where the building blocks and their assembly are inspired by biological examples. The key tool in translating these examples into the domain of engineering, has been self-assembly or self-organization. This book gathers a spectrum researchers who have not only furthered our knowledge of self-assembly using small molecules, polymers and colloidal particles as building blocks, but who have also shown it to be a practical tool in the assembly of an astonishing variety of devices, ranging from molecular electronics to biosensors.

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Nanobiosensors : From design to applications

Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors.

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Multiwavelength Mapping of Galaxy Formation and Evolution ; Proceedings of the ESO Workshop Held at Venice, Italy, 13-16 October 2003

The possibilities of astronomical observation have dramatically increased over the last decade. Major satellites, like the Hubble Space Telescope, Chandra and XMM Newton, are complemented by numerous large ground-based observatories, from 8m-10m optical telescopes to sub-mm and radio facilities. As a result, observational astronomy has access to virtually the whole electromagnetic spectrum of galaxies, even at high redshifts. Theoretical models of galaxy formation and cosmological evolution now face a serious challenge to match the plethora of observational data. In October 2003, over 170 astronomers from 15 countries met for a 4-day workshop to extensively illustrate and discuss all major observational projects and ongoing theoretical efforts to model galaxy formation and evolution. This volume contains the complete proceedings of this meeting and is therefore a unique and timely overview of the current state of research in this rapidly evolving field.

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Multirate Statistical Signal Processing

This book introduces a statistical theory for extracting information from signals that have di?erent sampling rates. This new theory generalizes the conventional (deterministic) theory of multirate systems beyond many of its constraints.Furthermore,itallowsfortheformulationofseveralnewproblems such as spectrum estimation, time-delay estimation and sensor fusion in the realm of multirate signal processing. I have arrived at the theory presented here by integrating concepts from diverse areas such as information theory, inverse problems and theory of - equalities. The process of merging a variety of concepts of di?erent origin results in both merits and shortcomings. The former include the fresh and - di?erentiated view of an amateur, providing scope of application. The latter include a lack of in-depth experience in each of the original ?elds. Granted, this may lead to gaps in continuity, however it goes without saying that a complete theory can seldom be achieved by one person and in a short time.

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Multiplicative Invariant Theory

Multiplicative invariant theory, as a research area in its own right within the wider spectrum of invariant theory, is of relatively recent vintage. The present text offers a coherent account of the basic results achieved thus far.. Multiplicative invariant theory is intimately tied to integral representations of finite groups. Therefore, the field has a predominantly discrete, algebraic flavor. Geometry, specifically the theory of algebraic groups, enters through Weyl groups and their root lattices as well as via character lattices of algebraic tori.

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