الصفحة 1
الصفحة 1
Ocular Traumatology
All aspects of ophthalmic trauma from the lid to the optic nerve of both mechanical and nonmechanical trauma are covered in this unique book. The focus is on practical issues and incorporates cutting-edge approaches, such as temporary keratosprosthesis, artificial iris diaphragm, and prophylactic retinectomy. This book explains and answers not simply the “when”, the “what”, and the “how”, but also the “why” questions. The information is based on epidemiologic and clinical data from evaluation to management.
Ocular Transporters in Ophthalmic Diseases and Drug Delivery
This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In Ocular Transporters in Ophthalmic Diseases and Drug Delivery, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium, and the transport of nutrients across the retinal pigment epithelium. It also provides an in-depth look at how mutations or dysfunction of specific transporters can contribute to various disorders in the eye, including blindness, and provides readers with potential targets and strategies to allow safe passage of therapeutic drugs into the eye.
Ocular Angiogenesis : Diseases, Mechanisms, and Therapeutics
Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches. Comprehensive and multidisciplinary, Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics offers a novel view of the clinical features of pathological angiogenesis in the eye, the molecular and environmental switches that govern vessel growth, and the tremendous opportunities for and progress made in the development of new therapeutics.
Neuronal Input Pathways to the Brains Biological Clock and their Functional Significance
Circadian rhythms are entrained daily by environmental photic and non-photic cues. The present review describes the anatomy and functional characteristics of the three major input pathways to the circadian clock mediating entrainment, the retino-hypothalamic tract (RHT), the geniculo-hypothalamic tract (GHT) and the midbrain raphe projection.
Molecular Neurosurgery with Targeted Toxins
Focuses on the highly successful use of the immunotoxins, 192 IgG-saporin and ME20.4-saporin, to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals. Also discussed are the uses of anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of central nervous system demyelination. Overview perspectives and, in some cases, more practical details are provided that allow the reader to appreciate exactly what is involved in using these agents. Both practical and theoretical, Molecular Neurosurgery With Targeted Toxins provides readers with not only the background to understand these techniques, but also numerous real-life examples that can be readily adapted to new purposes and an ever-increasing number of new targeted toxins.
Modeling Longitudinal Data
This book teaches the art and statistical science of modern longitudinal data analysis. The author emphasizes specifying, understanding, and interpreting longitudinal data models. He inspects the longitudinal data graphically, analyzes the time trend and covariates, models the covariance matrix, and then draws conclusions. The book has many figures and tables illustrating longitudinal data and numerous homework problems. The associated web site contains many longitudinal data sets, examples of computer code, and labs to re-enforce the material.
Medical Retina
Although the treatment of retinal diseases remains one of the most challenging fields in ophthalmology, the standard of knowledge has improved substantially over the past few years. The insight into basic mechanisms of disease has been expanded and novel diagnostic and therapeutic strategies have been developed, bridging the gap between laboratory and clinical science.
Mechanisms of the Glaucomas : Disease Processes and Therapeutic Modalities
In this book leaders in the various fields of glaucoma review our current understanding of glaucoma from epidemiology and genetics through molecular, cellular and tissue responses to the mechanisms of the glaucomas and the mechanisms by which we manage them.
Intrusion Detection and Correlation : Challenges and Solutions
Challenges and Solutions presents intrusion detection systems (IDSs) and addresses the problem of managing and correlating the alerts produced. This volume discusses the role of intrusion detection in the realm of network security with comparisons to traditional methods such as firewalls and cryptography. Challenges and Solutions analyzes the challenges in interpreting and combining (i.e., correlating) alerts produced by these systems. In addition, existing academic and commercial systems are classified; their advantage and shortcomings are presented, especially in the case of deployment in large, real-world sites. Challenges and Solutions is designed for a professional audience composed of researchers and practitioners in industry. This book is also suitable for graduate-level students in computer science.
Hypocretins : Integrators of Physiological Signals
The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with “wide awake” EEG patterns and EMG suppression.
Human semen analysis : From the WHO manual to the clinical management of infertile men
Intended to bridge the gap between the laboratory manual and the clinician by explaining in detail the test indication, its clinical utility, interpretation of results, and presenting a decision algorithm based on the test results. Thebook has 19 chapters grouped under seven sections that follow the chapters of the sixth edition of the WHO manual. Each chapter is written and reviewed by a team of senior clinicians, thus bringing a perspective that is truly clinically relevant. This book will be of great value to all clinicians involved in the management of male infertility and will also be of interest to laboratory scientists involved in semen testing by providing them with clinical perspectives of the test they perform. Human Semen Analysis: From the WHO Manual to the Clinical Management of Infertile Men is a useful guide for utilizing the WHO manual, interpreting test results, and deciding what subsequent clinical actions to take.
How to Examine the Nervous System
This textbook simplifies the apparent complexity of the neurological examination to make it completely understandable and satisfying to perform. With simple prose and numerous helpful illustrations, the author describes in detail reliable bedside examination techniques that will pinpoint the location of a lesion in the nervous system and lead to a resolution of the problem.
High-Dynamic-Range (HDR) Vision : Microelectronics, Image Processing, Computer Graphics
This first comprehensive account of high-dynamic-range (HDR) vision focusses on HDR real-time, high-speed digital video recording and also systematically presents HDR video transmission and display. The power of the eye-like, logarithmic optoelectronic conversion concept is demonstrated in machine-vision, medical, automotive, surveillance and cinematic applications, and it is extended to HDR sub-retinal implants for the vision impaired. While the book conveys the overall picture of HDR vision, specific knowledge of microelectronics and image processing is not required. It provides a quantitative summary of the major issues to allow the assessment of the state of the art and a glimpse at future developments. Selected experts share their know-how and expectations in this rapidly evolving art related to the single most powerful of our senses.
High Resolution Imaging in Microscopy and Ophthalmology : New Frontiers in Biomedical Optics
This book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting.
Handbook of vascular biometrics
This handbook provides the first comprehensive overview of biometrics exploiting the shape of human blood vessels for biometric recognition, i.e. vascular biometrics, including finger vein recognition, hand/palm vein recognition, retina recognition, and sclera recognition.
Handbook of Pediatric Retinal Disease
Distilling the essentials of ocular manifestations of pediatric neuroophthalmologic disorders and diseases into a portable, complete and authoritative pocket reference, this handbook offers a complete picture of how to best treat pediatric patients.
Graphics of Large Datasets : Visualizing a Million
Graphics are great for exploring data, but how can they be used for looking at the large datasets that are commonplace to-day? This book shows how to look at ways of visualizing large datasets, whether large in numbers of cases or large in numbers of variables or large in both. Data visualization is useful for data cleaning, exploring data, identifying trends and clusters, spotting local patterns, evaluating modeling output, and presenting results. It is essential for exploratory data analysis and data mining. New approaches to graphics are needed to visualize the information in large datasets and most of the innovations described in this book are developments of standard graphics. There are considerable advantages in extending displays which are well-known and well-tried, both in understanding how best to make use of them in your work and in presenting results to others. It should also make the book readily accessible for readers who already have a little experience of drawing statistical graphics. All ideas are illustrated with displays from analyses of real datasets and the authors emphasize the importance of interpreting displays effectively. Graphics should be drawn to convey information and the book includes many insightful examples.
Forest Road Operations in the Tropics
This book brings together information on road planning, location, design, construction and maintenance to support environmentally acceptable operations in tropical forests. It highlights the challenges of road operations in the tropics, includes techniques that have been shown to be successful, and discusses newer technologies. It is intended as a reference book for the forest engineer and others interested in the planning and management of tropical forests. Numerical examples are provided to provide clarity for interpreting graphs, procedures, and formulas. The book covers the various facets of road management from design objectives through practices to control environmental impacts.
Fluorescence angiography in ophthalmology
This atlas covers the basic principles of the new methods for fluorescein- and indocyanine green-angiography, as well as the high resolution imaging of fundus autofluorescence.
Fare astronomia con piccoli telescopi = Are astronomy with small telescopes
Giant tools are not necessarily required to produce scientifically valid results in the field of astronomy. Even the amateur with a small telescope, with a diameter of only 8-9 cm, can contribute to the science of the sky by making useful observations of the Sun, the Moon, planets, comets, asteroids, double or variable stars, nebulae and star clusters. The manual of M.K. Gainer explains what the minimum equipment is (a small telescope, a computer, a simple digital camera), how to use it, and what are the appropriate techniques to be adopted in the observations. It also offers schemes for interpreting and reducing the collected data, as well as forms to be filled in and sent to international collection centers.
