الصفحة 1
الصفحة 1
On The Interpretation of Treaties : The Modern International Law as Expressed in the 1969 Vienna Convention on the Law of Treaties
This book investigates the contents and structure of this system. By importing knowledge from linguistics, and pragmatics in particular, a model is established giving representation to the concept of a rule of interpretation. Drawing on this model, the book then proceeds to reconstruct the contents of the various rules of interpretation. To facilitate reference, the conclusions suggest a list of 44 rules, all of which can be invoked by appliers citing VCLT Articles 31-33.
Multiple Testing Procedures and Applications to Genomics
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. The methods are applied to a range of testing problems in biomedical and genomic research, including the identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments.
Multigenic and Induced Systemic Resistance in Plants
This comprehensive volume consists of a series of up-to-date reviews, each incorporating current models and knowledge related to mechanisms of resistance either expressed constitutively or induced systemically in plants. Each chapter covers a topic related to the phenomenon of plant resistance to fungal and bacterial pathogens, insects, nematodes, viruses or abiotic stress in plants, as well as the application of this knowledge to protect crops now and in the future. Researchers, upper-level undergraduate and graduate students, and those teaching courses in plant physiology, entomology and plant pathology will find this volume a much needed asset.
Molecular Chaperones in Health and Disease
Molecular chaperones are involved in a wide variety of essential cellular processes in living cells. A subset of molecular chaperones have been initially described as heat shock proteins protecting cells from stress damage by keeping cellular proteins in a folding competent state and preventing them from irreversible aggregation. Later it became obvious that molecular chaperones are also expressed constitutively in the cell and are involved in complex processes such as protein synthesis, intracellular protein transport, post-translational modification and secretion of proteins as well as receptor signalling. Hence, it is not surprising that molecular chaperones are implicated in the pathogenesis of many relevant diseases and could be regarded as potential pharmacological targets. Starting with the analysis of the mode of action of chaperones at the molecular, cellular and organismic level, this book will then describe specific aspects where modulation of chaperone action could be of pharmacological and therapeutic interest.
Modular Algorithms in Symbolic Summation and Symbolic Integration
Brings together two streams in computer algebra: symbolic integration and summation on the one hand, and fast algorithmics on the other hand. In many algorithmically oriented areas of computer science, the analysis of al gorithms placed into the lime light by DonKnuth’stalkat the 1970ICM –provides a crystal-clear criterion for success. The researcher who designs an algorithm that is faster (asymptotically, in the worst case) than any previous method receives instant gratification : her result will be recognized as valuable. Al as, the downside is that such results come along quite infrequently, despite our best efforts. An alternative evaluation method is to run a new algorithm on examples; this has its obvious problems, but is sometimes the best we can do. George Collins, one of the fathers of computer algebra and a great experimenter,wrote in 1969: “I think this demonstrates again that a simple analysis is often more revealing than a ream of empirical data (although both are important). ” Within computer algebra, some areas have traditionally followed the former methodology, notably some parts of polynomial algebra and linear algebra. Other areas, such as polynomial system solving, have not yet been amenable to this - proach. The usual “input size” parameters of computer science seem inadequate, and although some natural “geometric” parameters have been identified (solution dimension, regularity), not all (potential) major progress can be expressed in this framework. Symbolic integration and summation have been in a similar state.
Models of the Atomic Nucleus
Models of the Atomic Nucleus is a largely non-technical introduction to nuclear theory – an attempt to explain the nucleus in a way that makes nuclear physics as comprehensible as chemistry or cell biology. Unlike many other scientific fields, the "popularization" of nuclear physics has not previously been successful because many fundamental issues remain controversial and a unified theory of nuclear structure has not yet been established. The theme developed in this book is that the many models of nuclear theory each provide a partial perspective on the nucleus and that the many models can in fact be integrated into a coherent whole and expressed in terms of a lattice of nucleons.
Models for Polymeric and Anisotropic Liquids
Models should be as simple as possible, but no simpler. For the physics of polymeric liquids, whose relevant lengths and time scales are out of reach for first principles calculations, this means that we have to choose a minimum set of sufficiently detailed descriptors such as architecture (linear, ring, branched), connectivity, semiflexibility, stretchability, excluded volume, and hydrodynamic interaction. These 'universal' fluids allow the prediction of material properties under external flow- or electrodynamic fields, the results being expressed in terms of reference units, specific for any particular chosen material. This book provides an introduction to the kinetic theory and computer simulation methods needed to handle these models and to interpret the results. Also included are a number of sample applications and computer codes.
Modelling, Analysis and Optimization of Biosystems
Mathematical models in biology and medicine cannot be based on natural laws as it is the case with physics and chemistry. This is due to the fact that biological and medical processes are concerned with living organisms. Mathematical models, however, can be used as a language by which certain aspects of biological or medical processes can be expressed. In general, several mathematical models can be designed in order to describe a biological or medical process and there is no unique criterion which model gives the best description. This book presents several of these models and shows applications of them to different biological and medical problems. The book shows that operations research expertise is necessary in respect to modeling, analysis and optimization of biosystems.
Modeling of metal forming and machining processes : By finite element and soft computing methods
The physics of metal forming and metal removing is normally expressed using non-linear partial differential equations which can be solved using the finite element method (FEM). However, when the process parameters are uncertain and/or the physics of the process is not well understood, soft computing techniques can be used with FEM or alone to model the process.
Introduction to Complex Analysis in Several Variables
This book gives a comprehensive introduction to complex analysis in several variables. It clearly focusses on special topics in complex analysis rather than trying to encompass as much material as possible. Many cross-references to other parts of mathematics, such as functional analysis or algebras, are pointed out in order to broaden the view and the understanding of the chosen topics. A major focus is extension phenomena alien to the one-dimensional theory, which are expressed in the famous Hartog's Kugelsatz, the theorem of Cartan-Thullen, and Bochner's theorem.
International Handbook of Student Experience in Elementary and Secondary School
The International Handbook of Student Experience in Elementary and Secondary School is the first handbook of its kind to be published. It brings together in a single volume the groundbreaking work of scholars who have conducted studies of student experiences of school in Afghanistan, Australia, Canada, England, Ghana, Ireland, Pakistan, and the United States. Drawing extensively on students’ interpretations of their experiences in school as expressed in their own words, chapter authors offer insights into how students conceptualize and approach school, how students understand and address the ongoing social opportunities for and challenges in working with other students and teachers, and the multiple ways in which students shape and contribute to school improvement.
Integrable Systems in Celestial Mechanics
This work presents a unified treatment of three important integrable problems relevant to both Celestial and Quantum Mechanics. Under discussion are the Kepler (two-body) problem and the Euler (two-fixed center) problem, the latter being the more complex and more instructive, as it exhibits a richer and more varied solution structure. Further, because of the interesting investigations by the 20th century mathematical physicist J.P. Vinti, the Euler problem is now recognized as being intimately linked to the Vinti (Earth-satellite) problem. Here the analysis of these problems is shown to follow a definite shared pattern yielding exact forms for the solutions. A central feature is the detailed treatment of the planar Euler problem where the solutions are expressed in terms of Jacobian elliptic functions, yielding analytic representations for the orbits over the entire parameter range.
Information and Management Systems for Product Customization
This book consists of three parts. In the first part, within the theoretical basics of mass customization are discussed, and within the theoretical context, the main problems that are encountered with the implementation of mass customization are outlined. Part two deals with the development of appropriate information systems for mass customization. Part three discusses the topic of product modularity. More specifically, this part develops a managerial approach or tool to assess and solve complexity issues induced by the variety of needs expressed by customers. Using the tools and the conceptual frameworks developed in INFORMATION AND MANAGEMENT SYSTEMS FOR PRODUCT CUSTOMIZATION, the main problems of mass customization can be resolved. The book is the result of a privately funded, multi-year research project on "Modeling Planning, and Assessment of Business Transformation Processes in the area of Mass Customization."
High Order Difference Methods for Time Dependent PDE
Many books have been written on ?nite difference methods (FDM), but there are good reasons to write still another one. The main reason is that even if higher order methods have been known for a long time, the analysis of stability, accuracy and effectiveness is missing to a large extent. For example, the de?nition of the formal high order accuracy is based on the assumption that the true solution is smooth, or expressed differently, that the grid is ?ne enough such that all variations in the solution are well resolved. In many applications, this assumption is not ful?lled, and then it is interesting to know if a high order method is still effective. Another problem that needs thorough analysis is the construction of boundary conditions such that both accuracy and stability is upheld. And ?nally, there has been quite a strongdevelopmentduringthe last years, inparticularwhenit comesto verygeneral and stable difference operators for application on initial–boundary value problems.
Handbook of pharmaceutical manufacturing formulations ; Vol.2 : Uncompressed solid products
Covers uncompressed solids, which include formulations of powders, capsules, powders ready for reconstitution, and other similar products.Highlights from Uncompressed Solid Products, Volume Two include:the fundamental issues of good manufacturing practicesformulations for more than 400 pharmaceutical products, including currently approved products and innovative products such as small proteins, instantly liquifiable powders, and nanoparticlesaccess to US FDA guidelines, as well as all major guid
Handbook of pharmaceutical manufacturing formulations ; Vo.1 : Compressed solid products
An authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this first volume of a six-volume set, compiles data from FDA new drug applications, patent applications, and other sources of generic and proprietary formulations to cover the broad spectrum of GMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent
Globalization and Sustainable Development : Environmental Agendas
A characteristic of the present global ecological situation is increasing instability or— put another way—a crisis in the civilization system, the global scale of which is expressed through a deterioration of human and animal habitats. The most sub stantial features of global ecodynamics of the late 20th and early 21st centuries include the rapid increase in world population (mainly in developing countries), increase in the size of the urban population (considerable growth in the number of megalopolises), and increase in the scales of such dangerous diseases as HIV/AIDS, hepatitis, tuberculosis, etc.
Genomics of Tropical Crop Plants
Genomics of Tropical Crop Plants summarizes recent progress on genomic research, including the development of molecular markers, genomic and cDNA libraries, expressed sequence tags (ESTs), genetic and physical maps, gene expression profiles, and whole genome sequences for 20 tropical crop plants. It offers background information about the evolutionary origin and environments of tropical crop species, international programs that are addressing the needs of tropical agriculture, and the potential for new technologies to increase the productivity and value of tropical crops. This book provides new dimensions to growing information concerning temperate crops and their morphology, physiology, and parallel evolution in diverse plant lineages.
Formulas, ingredients and production of cosmetics technology of skin- and hair-care products in Japan
Provides the comprehensive knowledge and instruction necessary for researchers to design and create cosmetics products. The book’s chapters cover a comprehensive list of topics, which include, among others, the basics of cosmetics, such as the raw materials of cosmetics and their application; practical techniques and technologies for designing and manufacturing cosmetics, as well as theoretical knowledge; emulsification; sensory evaluations of cosmetic ingredients; and how to create products such as soap-based cleansers, shampoos, conditioners, creams, and others. The potential for innovation is great in Japan’s cosmetics industry. This book expresses the hope that the high level of dedicated research continues and proliferates, especially among those who are innovators at heart.
Fiscal Equalization : Challenges in the Design of Intergovernmental Transfers
These original essays highlight the state of knowledge in intergovernmental transfer design. They represent creative new thinking about challenging policy issues and offer useful options for policy makers. There is a genuine need for this book; it will become a 'benchmark' reference. I am impressed with its content, organization, readability, and fresh thematic approach.
