الصفحة 1
الصفحة 1
NEURO-COVID-19 : Neuroinvasive potential and neurological complications of SARS-CoV-2
From the earliest days of the COVID-19 pandemic, there have been reports of significant neurological and psychological symptoms following SARS-CoV-2 infection. This research paper is designed to examine the potential psychoneuroendocrine pathogenic mechanisms by which SARS-CoV-2 elicits psychiatric sequelae, as well as to posit potential pharmacologic strategies to address and reverse these pathologies. Following a brief overview of the presence and prevalence of neuropsychiatric manifestation in COVID-19 patients, we address mechanisms by which SARS-CoV-2 could enter or otherwise elicit changes in the CNS.
Neural Crest Induction and Differentiation
Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.
Natural products and human diseases : Pharmacology, molecular targets, and therapeutic benefits
Provides insight into the clinical and translational application of natural products in human diseases Details the impact of natural products on a molecular basis Describes the identification of biomarkers, therapeutic effects of phytochemicals, and and new targets
Multidetector-Row Computed Tomography : Scanning and Contrast Protocols
Multidetector-row computed tomography (MDCT) has advanced the approach to diagnostic assessment of many pathologies and now plays an integral role in imaging of both abdominal and cardiovascular diseases. The possibility to acquire diagnostic images with shorter scan duration, longer scan ranges, and/or thinner sections, MDCT has facilitated the opening of new horizons, such as interventional MDCT and functional imaging in stroke and oncology. In addition, advanced postprocessing techniques now permit high quality volumetric imaging in combination with maximum intensity projections, volume rendering, curved planar reformations and multiplanar reconstructions. This volume gathers contributions by internationally renowned specialists in the field who, through presenting their clinical experience, provide a thorough overview not only of MDCT and its practical applications, but also of workflow management in everyday clinical practice. Focussing on scanning and contrast protocols, the current advantages and disadvantages of non-enhanced vs. enhanced MDCT are discussed, along with insights into likely future developments. The volume represents an up-to-date source of technical and practically-oriented clinical information which should prove of great benefit to all who wish to improve or consolidate their knowledge and expertise in MDCT.
MRI of the Temporomandibular Joint : Correlation Between Imaging and Pathology
This book is the outcome of a fruitful, long-standing cooperation between expert radiologists and clinicians, and explains the most relevant features and technical requirements that are needed to optimally conduct and assess MR examinations for temporomandibular joint (TMJ) pathologies.
MRI of the Heart and Vessels
In recent years magnetic resonance imaging (MRI) has enriched the technological potential available for the characterization of cardiovascular pathologies, adding substantial advantages to other non-invasive techniques. This technique, which is intrinsically digital and has reduced operator dependency, allows the performance of image analysis in a quantitative and reproducible manner. In virtue of its added diagnostic value and inherent refinements that allow construction of two- and three-dimensional images, MRI is gaining a primary role in the histopathological and physiopathological understanding of a large number of pathologies concerning the heart and vessels. This text is addressed both to MRI operators seeking specific technical information and to clinicians who wish to have a better understanding of the diagnostic and management advantages that MRI can offer.
Medicina delletà prenatale : Prevenzione, diagnosi e terapia dei difetti congeniti e delle principali patologie gravidiche = Prenatal medicine: Prevention, diagnosis and therapy of congenital defects and the main pathologies of pregnancy
This text aims to respond to the actual need to bring together in a single and updated reference text notions and data from different backgrounds, all essential for optimal monitoring of pregnancy.
Integrated Cytology of Cerebrospinal Fluid
Integrated Cytology of Cerebrospinal Fluid is a practical guide to this method used in the diagnosis of different pathologies. High-quality slides depict the common cerebrospinal fluid cell types, cell anomalies in inflammatory conditions and neoplastic and non-neoplastic disorders, and cases with contaminants.
Inflammation and cancer : Methods and protocols
Discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers.And covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states.
Infections à papillomavirus : État des connaissances, pratiques et prévention vaccinale = Human papillomavirus infections : Current knowledge, practices and vaccination prevention
The impact of papillomavirus (HPV) infection is considerable. More than one in two women has been exposed to HPV in her lifetime and around 10% will develop a chronic infection. Of these, 20% will develop cervical cancer in the absence or failure of screening. In France, high-risk HPV infection causes 80,000 precancerous lesions, 3,400 cervical cancers and the death of 1,000 women every year. Smear screening performed at a regular rate and according to quality standards has resulted in a significant decrease in incidence and mortality over the past 20 years. However, despite this considerable success, the so-called preventable disease has not been eradicated; testing is a complex process that only benefits part of the population while those who benefit endure its weaknesses. Optimization of screening and treatment is now made possible by the use of innovative techniques including the smear in liquid suspension, the HPV test, and soon viral genotyping and molecular markers guaranteeing maximum protection. Because cervical cancer is the result of chronic HPV infection, we already have the extraordinary chance to prevent it with a prophylactic vaccine. This progress will have a major impact on our practices as it happens in a poorly prepared medico-sociological environment. This resolutely practical and educational book provides an overview of knowledge and perspectives on HPV infection and its associated pathologies while deciphering the new challenges and practices in the vaccine era.
Imaging of the Temporomandibular Joint
This book is designed to meet the demand for a comprehensive yet concise source of information on temporomandibular joint (TMJ) imaging that covers all aspects of TMJ diagnostics. Readers will find clear presentation of the imaging findings in the full range of TMJ pathologies, from intrinsic pathological processes to invasion by lesions of the temporal bone and mandibular condyle.
Imaging of the liver and Intra-hepatic biliary tract ; Vol.2 : Tumoral pathologies
This is the second of two volumes that together provide a comprehensive analysis of the embryology, normal anatomy, and pathology of the liver and intrahepatic biliary tract as seen on modern diagnostic imaging techniques. In this second volume, readers will find comprehensive description and illustration of the imaging appearances of tumoral pathologies, both in the “normal liver” and in the context of chronic liver disease and liver cirrhosis. In addition, the imaging findings in relation to different treatment approaches are presented, with extensive coverage of imaging of tumor response and post-treatment changes.
Imaging of the liver and Intra-hepatic biliary tract ; Vol.1 : Imaging techniques and non-tumoral pathologies
This is the first of two volumes that together provide a comprehensive analysis of the embryology, normal anatomy, and pathology of the liver and intrahepatic biliary tract as seen on modern diagnostic imaging techniques. In this volume, readers will find fundamental information on embryology, radiological anatomy, and anatomic variants. A thorough introduction is then provided to each imaging technique, including ultrasound, computed tomography, magnetic resonance imaging, nuclear medicine techniques, angiography, and interventional radiology. The remainder of the volume is devoted to non-tumoral pathology of the liver and intra-hepatic biliary tract
Il metodo clinico rivisitato : Lezioni e seminari di clinica medica = The Clinical Method Revisited : Clinical Medical Lectures and Seminars
This volume, dedicated to medical students who live the exciting moment of initiation into the medical profession, is structured in eleven didactic modules, which are developed according to the typical sequence of problem solving revised in the light of the EBM method (presentation of problem, formulation and testing of hypotheses, formulation of clinical and background questions, comparison with international literature, answer to questions, application to the clinical case and possible formulation of recommendations for practice, case management). Linked to them are eight in-depth analyzes structured as compendia of evidence (Evidence compendia, in the style of Clinical Evidence), in which a series of background questions relating to complex pathologies, of high prevalence and of considerable interest for the hospital internist and of the territory. Although fundamentally designed for teaching, the book can also be a useful tool for all those who practice medicine by placing the man with his disease at the center of the diagnostic-therapeutic procedure.
Handbook of Pathogens and Diseases in Cephalopods
The aim of this book is to facilitate the identification and description of the different organs as well as pathogens and diseases affecting the most representative species of cephalopods focussed on Sepia officinalis, Loligo vulgaris and Octopus vulgaris. These species are valuable ‘morphotype’ models and belong to the taxonomic groups Sepioidea, Myopsida and Octopoda, which include most of the species with a high market value and aquaculture potential. The study is based on photographs at macroscopic and histological level in order to illustrate the role of the most important pathogens and related diseases from the view of a pathological diagnosis. The reader is able to familiarize with functional anatomy, necropsy and general histology of adults and paralarvae, as well as with the identification of different pathogens and pathologies. This work is thus an invaluable guide for the diagnosis of cephalopod diseases. Besides including pathogens for non-European cephalopod species, it also provides a useful contribution encouraging marine pathologists, parasitologists, veterinarians and those involved in fishery sanitary assessments, aquarium maintenance and aquaculture practices aiming to increase their knowledge about the pathology of cephalopods.
Guyton and Hall textbook of medical physiology
Employs a distinctive format to ensure maximum learning and retention of complex concepts. A larger font size emphasizes core information, while supporting information, including clinical examples, are detailed in smaller font and highlighted in pale blue - making it easy to quickly skim the essential text or pursue more in-depth study. This two-tone approach, along with other outstanding features, makes this bestselling text a favorite of students worldwide. Offers a clinically oriented perspective written with the clinical and preclinical student in mind, bridging basic physiology with pathophysiology. Focuses on core material and how the body maintains homeostasis to remain healthy, emphasizing the important principles that will aid in later clinical decision making. Presents information in short chapters using a concise, readable voice that facilitates learning and retention. Contains more than 1,200 full-color drawings and diagrams - all carefully crafted to make physiology easier to understand. Features expanded clinical coverage including obesity, metabolic and cardiovascular disorders, Alzheimer's disease, and other degenerative diseases.
Évaluation des troubles neuropsychologiques en vie quotidienne = Assessment of neuropsychological disorders in daily life
Neurological diseases such as stroke, head trauma, Alzheimer's disease pose a public health problem. They affect all ages, from children to the elderly. They affect the possibilities of autonomy in daily life, the possibilities of social or professional integration. In these pathologies, neuropsychological disorders: disorders of language, memory, attention, etc., are the source of crucial difficulties. Cognitive tests performed by psychologists are essential for their diagnosis, but do not on their own make it possible to prejudge the difficulties encountered by people in their everyday life. This book presents an original approach to neuropsychological disorders, by describing specific assessments describing difficulties in daily life, in order to better understand them and to quantify their impact. The second part of the book develops the consequences in clinical practice in particular populations - children and the elderly - or the social objective of the evaluation, in particular school integration, professional integration and driving. Finally, the relevance of these assessments in the context of recent laws on disabled people as well as the development of compensation for bodily injury after an accident are also discussed.
Enzymes and drugs
Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances.
Endovascular Aneurysm Repair : From Bench to Bed
Endovascular procedures have a tremendous impact upon modern patient care. This book summarizes covered stent-graft applications in the experimental and clinical settings. Excellent illustrations document the acute and chronic behavior of stent-grafts within the vascular system including diagnostic imaging, histologic work-up and schematic drawings. A large amount of experience on intravascular ultrasound-based repair of aortic pathologies is presented. Physicians interested in the endovascular field will find this book a very stimulating resource.
Emerging Pathologies in Cardiology ; Proceedings of the Mediterranean Cardiology Meeting 2005
The book aims to give the most up-to-date information about the epidemiology, the pathophysiology, the diagnosis and the new treatments of the Emerging Pathologies in Cardiology. It presents the state of the art on Acute Coronary Syndromes, Sudden Cardiac Death, Heart Failure, Atrial Fibrillation, Syncope and Prevention of Global Cardiovascular Risk which are some of the emerging pathologies urging investigators to develop many and more sophisticated pharmacological, electrical or mechanical therapies. The volume chapters are written by world-renowned leading experts in these fields, and present a detailed analysis of the most recent developments in the treatment of the above mentioned cardiac pathologi
