الصفحة 1
الصفحة 1
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Neuropsychiatric Disorders : An Integrative Approach

This multidisciplinary book includes current research papers and reviews in the areas of basic neuroscience, neural mechanisms underlying neurodegenerative disorders. It further includes new approaches for neuroprotective treatments, clinical, neurobiological and treatment aspects of psychiatric disorders. The book was conceived as a celebration of the professional life and work of Peter Riederer to mark the occasion of his retirement.

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Minimally Invasive Neurosurgery and Neurotraumatology

Neurotraumatology patients present an enormous challenge to society. Neuros- gical management of brain and spinal cord injury has been a frustrating area, as s- gical methods, especially in moderate and severe injuries, have been limited to control of brain and spinal compression, control of intracranial pressure with its expected effect on cerebral blood flow, and structural repair of the supporting structures (skull, spine, brain and spinal cord coverings). Achieving the best outcome for the neu- traumatology patient, however, requires much more than that.

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Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases

Improved understanding of role of protein dysmetabolism in neurodegeneration promises to improve diagnoses, facilitate the development of biological markers relevant to disease pathophysiology, and provide tractable therapeutic targets. This Fondation IPSEN conference summary provides an update on the latest advances of the role of protein misfolding in the pathophysiology of neurodegenerative diseases.

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Genome editing in neurosciences

Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.

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