الصفحة 1
الصفحة 1
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Multiple Stressors : A Challenge for the Future

This book publishes the Proceedings of the NATO Advanced Research Workshop on Multipollution Exposure and Risk Assessment, Ecotoxiclogical risk from multiple stressors covers any situation where org- isms are exposed to a combination of environmental stressors. These include physical and chemical pollutants as well as other stressors such as parasites and environmental impact (e. g. , climate change or habitat loss). The combi- tion of stressors can result in increased risk to organisms (either additive or synergistic effects) or decreased effects (protective or antagonistic effects). The multiple stressor challenge is an international, multi-disciplinary problem requiring an international, multi-disciplinary approach. The c- rent approach to multiple stressors is to examine one stressor at a time and assume additivity.

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Molecular Mechanisms of Parasite Invasion

All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.

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Micromammals and Macroparasites : From Evolutionary Ecology to Management

Small mammals are among the most ubiquitous and important components of terrestrial ecosystems. They have coevolved, and now coexist, with a diverse array of parasites, such that not only are all aspects of their biology influenced by parasitism but they also play key roles in the transmission and maintenance of parasitic diseases. This book provides a comprehensive survey of the diversity and biology of metazoan parasites affecting small mammals, of their impact on host individuals and populations, and of the management implications of these parasites for conservation biology and human welfare. Designed for a broad, multidisciplinary audience, it will be an essential resource for researchers, students, and practitioners alike in the fields of parasitology, evolutionary ecology, wildlife management, and conservation biology.

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Methods of microarray data analysis V

In this volume, all investigators analyzed a single dataset on the lifecycle of the most deadly of malaria parasites, Plasmodium falciparum. The emphasis this year is on the application of novel and existing computational methodologies towards infectious disease. We highlight an introductory chapter by Raphael D. Isokpehi, a leading expert in the field of malaria. Ten of the papers presented at the conference are included, which range from the inference of genetic networks to the analysis of the spatial correlation of array data. This book is an excellent reference for academic and industrial researchers who want to keep abreast of the state-of-the-art in microarray data analysis.

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Interface oral health science 2014 : Innovative research on biosis-abiosis intelligent interface

The Tohoku University Graduate School of Dentistry first introduced the concept of “Interface Oral Health Science”, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganisms cohabiting the surfaces of the oral cavity, and (3) biomaterials that are used for the rehabilitation of oral functions. In addition, (4) these systems are subject to severe and complex mechanical forces. Therefore, it is critical to promote dental studies that integrate a wide range of interdisciplinary research as medicine, agriculture, material science, engineering, and pharmacology.

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Interface Oral Health Science 2011

A compendium of the research presented at symposiums held in 2011 by the Tohoku University Graduate School of Dentistry and by the Forsyth Institute. Its publication is intended provide further impetus for the progress of oral science and health, pointing the way for dental research for future generations.

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Interface Oral Health Science 2007 ; Proceedings of the 2nd International Symposium for Interface Oral Health Science, Held in Sendai, Japan, Between 18 and 19 February, 2007

Interface Oral Health Science is a major theme for next-generation dental research. That theme is based on the innovative concept that healthy oral function is provided by biological and biomechanical harmony among three systems: oral tissues including the teeth, mucosa, bones, and muscles (host); parasitic microorganisms of the oral cavity (parasites); and biomaterials. The concept posits that oral diseases such as dental caries, periodontal disease, and tempo- mandibular disorders should be interpreted as interface diseases that result from disruption of the intact interfaces among these systems. The uniqueness of this concept rests on the fact that it not only encompasses the entire fi eld of dentistry and dental care, but also expands the common ground shared with many other fields, including medicine, pharmaceutical science, agriculture, material science, and engineering.

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Immunobiology of natural killer cell receptors

Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.

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Imaging of Parasitic Diseases

This book provides an overview of the imaging findings of parasitic diseases using modern imaging equipment. The chapters consist of short descriptions of causative pathogens, epidemiology, modes of transmission, pathology, clinical manifestations, laboratory tests, and imaging findings.

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Imaging Cellular and Molecular Biological Functions

Imaging cellular and molecular biological function’ provides a unique selection of essays by leading experts, aiming at scientist and student alike who are interested in all aspects of modern imaging, from its application and up-scaling to its development. Indeed the philosophy of this volume is to provide student, researcher, PI, professional or provost the means to enter this applications field with confidence, and to construct the means to answer their own specific questions.

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Handbook of Pathogens and Diseases in Cephalopods

The aim of this book is to facilitate the identification and description of the different organs as well as pathogens and diseases affecting the most representative species of cephalopods focussed on Sepia officinalis, Loligo vulgaris and Octopus vulgaris. These species are valuable ‘morphotype’ models and belong to the taxonomic groups Sepioidea, Myopsida and Octopoda, which include most of the species with a high market value and aquaculture potential. The study is based on photographs at macroscopic and histological level in order to illustrate the role of the most important pathogens and related diseases from the view of a pathological diagnosis. The reader is able to familiarize with functional anatomy, necropsy and general histology of adults and paralarvae, as well as with the identification of different pathogens and pathologies. This work is thus an invaluable guide for the diagnosis of cephalopod diseases. Besides including pathogens for non-European cephalopod species, it also provides a useful contribution encouraging marine pathologists, parasitologists, veterinarians and those involved in fishery sanitary assessments, aquarium maintenance and aquaculture practices aiming to increase their knowledge about the pathology of cephalopods.

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Genome Mapping and Genomics in Arthropods

Mapping of animal genomes has generated huge databases and several new concepts and strategies, which are useful to elucidate origin, evolution and phylogeny. Genetic and physical maps of genomes further provide precise details on chromosomal location, function, expression and regulation of academically and economically important genes. The series "Genome Mapping and Genomics in Animals" provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world.Insects and other arthropods, the largest group of animals in number of species, have global impact on agriculture, industry, human health and environment. They are of particular economic importance for food production as pollinators, for natural products like silk and also as pests and parasites. Arthropods covered in this volume include honeybee, bumblebee, the parasitic Jewel Wasp, silkworm, pea aphid, mosquito, Hessian fly and tick.

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Food-Borne Parasitic Zoonoses : Fish and Plant-Borne Parasites

The focus of this book is on those zoonoses that are transmitted by fish, plant and invertebrate foods. While people, especially those living in developed countries, are commonly aware of meat-borne zoonoses such as trichinellosis and cysticercosis, fewer are acquainted with parasitic diseases caused by liver, lung and intestinal flukes, fish-borne tapeworms, and tissue roundworms. This book reviews not only the prevalence and distribution of these zoonoses, including available health and economic impact data, but also highlights gaps in our knowledge base that must be filled in order to gain insights on approaches to prevention. The topics on epidemiology, diagnosis, and clinical aspects emphasize knowledge gaps that limit a full understanding of these zoonoses, and target where greater research investments on these parasitic diseases should be focused.

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Foodborne Parasites

Microbiologists are being challenged as foodborne outbreaks are increasingly being observed worldwide. Most of these outbreaks are associated with viral and bacterial pathogens such as Campylobacter, Salmonella, and lately Escherichia coli O157:H7.Foodborne Parasites examines the two major parasite groups that are transmitted via water or foods: the protozoa, which are single celled organisms, and the helminths. The helminths are classified in three sub groups: cestodes (tapeworms), nematodes (round worms), and trematodes (flukes). To better understand their significance, each chapter covers the biology, mechanisms of pathogenesis, epidemiology, treatment, and inactivation of these parasites.

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Foodborne Diseases

In Foodborne Diseases, leading authorities present a broad overview of the microbial pathogens and toxins associated with foodborne illness while discussing pathogenicity, clinical epidemiology, diagnosis, and treatment. The chapters of this volume cover a wide variety of bacterial pathogens, viruses, protozoans, and parasites, as well as microbial toxins, and also address alternatives to antibiotics, risk assessment, irradiation and other sanitation procedures, and molecular techniques for detecting foodborne pathogens. Additionally, the acclaimed authors discuss pathogen control strategies and look toward future innovations in food safety technology. Covering essential foodborne pathogens, assessment and treatment, Foodborne Diseases is an essential reference for infectious disease specialists, microbiologists, and industrial and research-based scientists in food safety.

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Entomology

The author’s long-held belief that an introductory entomology course should present a balanced treatment of the subject is reflected in the continued arrangement of the book in four sections: Evolution and Diversity, Anatomy and Physiology, Reproduction and Development, and Ecology. For the third edition, all chapters have been updated. This includes not only the addition of new information and concepts but also the reduction or exclusion of material no longer considered "mainstream", so as to keep the book at a reasonable size.

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Encyclopedia of Parasitology

Knowledge in the field of parasitology must be kept at a high level and up to date in order to fight a parasitosis as quickly and effectively as possible.The third edition of the “Encyclopedia of Parasitology” contributes to these goals in several ways: the number of entries has been increased by about 30%, the content has been even more improved by adding more tables and figures. The extensive linking between definitions and essays facilitates information within a minimum of time.More than 40 international contributors, who are well known specialists in their fields, give a comprehensive review of all parasites and therapeutic strategies in veterinarian and human parasitology.The third edition is now presented as two volumes in A-Z format and additionally in an electronic online version.

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Empire under the microscope : Parasitology and the British literary imagination, 1885–1935

This book considers science and empire, and the stories we tell ourselves about them. Emilie Taylor-Pirie examines a wealth of archival material including medical lectures, scientific publications, popular biography, and personal and professional correspondence, alongside novels, poems, newspaper articles, and political speeches, to excavate the shared vocabularies of literature and medicine. She demonstrates how forms such as poetry and biography; genres such as imperial romance and detective fiction; and modes such as adventure and the Gothic, together informed how tropical diseases, their parasites, and their vectors, were understood in relation to race, gender, and nation.

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Drug Targets in Kinetoplastid Parasites

The book contains 12 chapters contributed by eminent scientists working in this field. The articles deal mainly with two aspects: visual identification of targets and identification of therapeutic agents.Several targets like kDNA replication machinery, purine salvage pathway, purine and pyrimidine biosynthetic pathway, histone deacetylase, DNA topoisomerases, membrane transporter proteins, glycoproteins and glycolipids are discussed in this book. Since current treatments for kinetoplastid parasitic diseases are far from ideal, there is an urgent and genuine need to develop newer compounds as antiparasitic drug candidates. Therefore evelopment of some lead compounds against these parasites as well as drug resistance are also included in this book. Moreover the vast amount of information generated after publication of the "Trytrip" genome sequence now makes possible several new approaches for target identification and discovery of therapeutic agents. This book is an outcome of the contributions of many scientists working in this important area.

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Diagnosis of pathogenic microorganisms : Causing infectious diseases

Infectious diseases are caused by the pathogenic microbial organisms. These microbes can multiply and can cause an infection, once they enter the body. Infectious diseases are transmissible, and may cause mild to life-threatening illnesses. It can be airborne, waterborne, foodborne, and soilborne. It can be spread through direct contact (human to human, animal to human). It has also been one of the leading causes of human deaths. Therefore, there is a need to have rapid diagnostic methods to prevent and control these diseases. This book titled “Diagnosis of Pathogenic Microorganisms Causing Infectious Diseases” will help the scientific community to understand the transmission dynamics of some infectious diseases of public health importance.

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