الصفحة 1
الصفحة 1
New strategies in treating and diagnosing of Myeloid Leukemia
Leukemia is a cancer of white blood cells. It is characterized by an abnormal accumulation of WBC in the bone marrow which leads to bone marrow failure. in this project, we will observe myeloid leukemias (acute & chronic), Clinical Practice Guidelines for leukemia provide recommendations on the diagnostic evaluation, and applied treatment in Syria and Germany for induction and consolidation for patients and we're going to devote a special paragraph on therapy with monoclonal antibodies. Gilteritinib are new therapies for acute myeloid leukemia and we're going to suggest them in detail.
New Frontiers in Applied Artificial Intelligence ; 21st International Conference on Industrial, Engineering and Other Applications of Applied Intelligent Systems, IEA/AIE 2008 Wrocław, Poland, June 18-20, 2008 Proceedings
The 75 revised full papers presented were carefully reviewed and selected from 302 submissions. The papers are organized in topical sections on computer vision, fuzzy system applications, robot and manufacturing, data mining and KDS, neural networks, machine learning, natural language processing, internet application and education, heuristic search, application systems, agent-based system, evolutionary and genetic algorithms, knowledge management, and other applications. The book concludes with 15 contributions from the following special sessions: knowledge driven manufacturing systems, joint session on adaptive networked systems and fuzzy knowledge bases, and software agents and multi-agent systems.
Molecular Mimicry : Infection Inducing Autoimmune Disease
The conceptual basis for molecular mimicry was first defined in the early 1980s when monoclonal antibodies against viruses were also shown to react with non-viral host protein; in this case, measles virus phosphoprotein cross-reacted with host cell cytokeratin, herpes simplex virus type 1 with host-cell vimentin and vaccinia virus with host-cell intermediate filaments. Following this discovery, others emerged, again at the clonal level, that T cell clones against proteins from a variety of infectious agents also reacted with host antigenic determinants. The clonal distinction was imperative fo.
Modern avenues in metal-nucleic acid chemistry
Provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues. More recently, also as a consequence of the advent of supramolecular chemistry, advancements in nanochemistry, and new bio-analytical methods, novel aspects of this field have emerged. MILS-25 gives a state-of-the-art account on the present state of research in this field, addressing, among others, porous materials, non-covalent interactions, stimuli-responsive bioconjugates, DNA-templated metal arrays and nanoclusters, genotyping, guanine quadruplexes, and riboswitches.
Model Driven Engineering Languages and Systems ; Vol. 4199 ; 9th International Conference, MoDELS 2006, Genova, Italy, October 1-6, 2006, Proceedings
This book constitutes the refereed proceedings of the 9th International Conference on Model Driven Engineering Languages and Systems (formerly the UML series of conferences), MoDELS 2006, held in Genova, Italy, in October 2006. The 51 revised full papers and 2 invited papers presented were carefully reviewed and selected from 178 initial submissions. The papers are organized in topical sections on evaluating UML, MDA in software development, concrete syntax, applying UML to interaction and coordination, aspects, model integration, formal semantics of UML, security, model transformation tools and implementation, analyzing dynamic models, specifying transformations, MOF, bridging models, risk, trust and dependability, tool environments, OCL, roundtrip engineering, real time and embedded systems, as well as workshops, tutorials and panels.
Model Driven Engineering Languages and Systems ; Vol. 3713 : 8th International Conference, MoDELS 2005, Montego Bay, Jamaica, October 2-7, 2005, Proceedings
Constitutes the proceedings of the 8th International Conference on Model Driven Engineering Languages and Systems, MoDELS 2005, held in Montego Bay, Jamaica, in October 2005. This book includes 52 papers and 2 keynote abstracts. It covers such topics as process modelling, product families, state/behavioral modeling, design strategies and more.
Mobile Communications : Re-negotiation of the Social Sphere
Mobile Communications: Renegotiation of the Social Sphere surveys some of the broader issues associated with the adoption and use of mobile communication, and explores developing areas of inquiry. Mobile communications are looked at in the context of other types of mediated interaction (e-mail, instant messaging, Wi-Fi, landline telephone etc.), thus demonstrating the uniqueness of this form of communication and how it is influencing the renegotiation of the social sphere. A truly international set of contributors consider how mobile communication has impacted on society and reflect on how it is used (and sometimes resented) in various public and private spaces. They provide an in-depth analysis of specific areas which complement our understanding of the phenomena including: • The psychological dimensions of mobile communication (addiction, proclivity to be disturbed by others use of the mobile phone), • The linguistics of mobile communication, and • The understanding of mobile communication’s commercialisation. This book will be a valuable addition to any researcher’s or professional’s reading material in the area of interaction of technology and society, providing the reader with a broad insight and specific knowledge of how mobile communication is reformulating the social sphere.
Microorganisms in the deterioration and preservation of cultural heritage
This book offers a comprehensive overview of the role and potential of microorganisms in the degradation and preservation of cultural materials (e.g. stone, metals, graphic documents, textiles, paintings, glass, etc.).
Metainformatics ; International Symposium, MIS 2004, Salzburg, Austria, September 15-18, 2004, Revised Selected Papers
Constitutes the refereed post-proceedings of the Metainformatics Symposium, MIS 2004, held in Salzburg, Austria. This book reviews 17 papers that are devoted to finding useful abstractions, analytical frameworks, and systems that improve the understanding of the underlying structure of disciplines and families of systems within computer science.
Introduction to biologic and biosimilar product development and analysis
Gives a concise introduction to development and analysis of pharmaceutical biologics for those in the pharmaceutical industry who are switching focus from small molecules to biologics processing, analysis, and delivery. In order to maintain a limited focus, Introduction to Biologic and Biosimilar Product Development and Analysis, will deal only with peptides, proteins and monoclonal antibodies.
International Trade and Multinational Activity : Heterogeneity of Firms, Incentives for Foreign Direct Investment, and International Business Cycle Dynamics
During the last 25 year, the neoclassical Heckscher-Ohlin trade theory has been extended to the ‘new’ trade theory by including imperfect competition and fixed costs into the analysis of trade relations. Furthermore, these micro-oriented trade models are increasingly used to analyze macro-oriented questions. Chapter 2 of this study investigates the dynamic welfare effects of exposure to trade in a new trade model, which is extended by firm heterogeneity.
Institutions, Sustainability, and Natural Resources : Institutions for Sustainable Forest Management
A new economic theory, rather than a new public policy based on old theory, is needed to guide humanity toward sustainability. Institutions are a critical dimension of sustainability and sustainable forest management, and economic analysis of institutional dimension requires an inclusionist rather than an exclusionist approach. This book provides a systematic critique of neoclassical economic approaches and their limitations with respect to sustainability. Leading institutional economists discuss theoretical perspectives about appropriate institutions for sustainable forest management, markets for environmental services, deforestation and specialization, and some country experiences about Kyoto Protocol, international trade, biodiversity conservation, and sustainable forest management in general. The book includes the ideas from old as well as new institutional economics and discusses the main features of Post-Newtonian economics.This book follows a companion book, Economics, Sustainability, and Natural Resources: Economics of Sustainable Forest Management, volume 1 of the series.
Imaging of the Sternocostoclavicular Region
Review of the normal histopathological anatomy, imaging techniques and diagnostic findings for a broad spectrum of clinical problems, including a classification of inflammatory syndromes previously described under several different terms.
High value fermentation products ; Vol.1 : Human health
This book describes relevant aspects of industrial-scale fermentation, an expanding area of activity, which already generates commercial values of over one third of a trillion US dollars annually, and which will most likely radically change the way we produce chemicals in the long-term future. From biofuels and bulk amino acids to monoclonal antibodies and stem cells, they all rely on mass suspension cultivation of cells in stirred bioreactors, which is the most widely used and versatile way to produce.
Gradients in a Tropical Mountain Ecosystem of Ecuador
This volume addresses a multitude of ecologically relevant aspects: macro- and microclimate; physics, chemistry and biology of soils; water relations, matter turnover and nutrient availability; plant growth and biomass partitioning; floral composition and plant life forms; vegetation structure and dynamics; organismic interactions, diversity and population biology of birds, moths and microarthropods; forest management, and reforestation with indigenous species; ethnobotanical and social aspects. New hypotheses are presented with regard to biodiversity and ecosystem functioning, as well as sustainable management of an ecosystem in a biodiversity hotspot.
Global Change and Mountain Regions : An Overview of Current Knowledge
Mountain regions occupy about a quarter of the global terrestrial land surface and provide goods and services to more than half the humanity. Global environmental change threatens the integrity of these systems and their ability to provide the goods and services upon which humanity has come to depend. This book gives an overview of the state of research in fields pertaining to the detection, understanding and prediction of global change impacts in mountain regions. More than 60 contributions from paleoclimatology, cryospheric research, hydrology, ecology, and development studies are compiled in this volume, each with an outlook on future research directions.
Evaluation of Multilingual and Multi-modal Information Retrieval ; 7th Workshop of the Cross-Language Evaluation Forum, CLEF 2006, Alicante, Spain, September 20-22, 2006, Revised Selected Papers
This book covers Multilingual Textual Document Retrieval, Domain-Specifig Information Retrieval, i-CLEF, QA@CLEF, ImageCLEF, CLSR, WebCLEF and GeoCLEF.
Economics, Sustainability, and Natural Resources: Economics of Sustainable Forest Management
The economics of sustainability is much more complex than the neoclassical (Newtonian) economic approach to economic efficiency. Forest resources provide the ideal starting point for the economic analysis of sustainability. This book provides a systematic critique of neoclassical economic approaches and their limitations with respect to sustainability. Leading economists from different streams of economics discuss key economic aspects of sustainability and sustainable forest management including complexity, ethical issues, consumer choice theory, intergenerational equity, non-convexities, and multiple equilibria. This is the book which integrates different streams of economics – complexity theory, behavioral economics, post-Keynesian consumer choice theory, social choice theory, and non-convexities – and suggests the main features of Post-Newtonian economics.
Economics of the Environment : Theory and Policy
Interprets nature and the environment as a scarce resource. It offers a theoretical study of the allocation problem and describes different policy approaches to the environmental problem. The entire spectrum of the allocation issue is studied: the use of the environment in a static context, international and trade aspects of environmental allocation, regional dimensions, global environmental media, environmental use over time and under uncertainty. The book incorporates a variety of economic approaches, including neoclassical analysis, the public-goods approach, benefit-cost analysis, property-rights ideas, economic policy and public-finance reasoning, international trade theory, regional science, optimization theory, and risk analysis. The different aspectsof environmental allocation are studied in the context of a single model that is used through the book.
Dynamical Oceanography
This textbook provides a mathematical introduction to the theory of large-scale ocean circulation and is accessible for readers with an elementary knowledge of mathematics and physics, including continuum mechanics and solution methods for ordinary differential equations. The book consists of four parts. Part I (chapters 1 - 4) is a very brief introduction to ocean circulation and the mathematical formulation of the governing equations of ocean flows. In addition, concepts are introduced that are necessary to describe and understand large-scale ocean currents. In part II (chapters 5 - 10), the theory of mid-latitude wind-driven ocean circulation is presented. Part III (chapters 11 - 12) focuses on the understanding of equatorial currents and El Nino. In the last part IV, chapters 13 - 16, the theory of planetary scale flows is presented, covering topics such as the thermocline problem, the Antarctic Circumpolar Current, the stability of the thermohaline circulation and the Arctic Ocean circulation.
