الصفحة 1
الصفحة 1
Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology
In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).
On The Interpretation of Treaties : The Modern International Law as Expressed in the 1969 Vienna Convention on the Law of Treaties
This book investigates the contents and structure of this system. By importing knowledge from linguistics, and pragmatics in particular, a model is established giving representation to the concept of a rule of interpretation. Drawing on this model, the book then proceeds to reconstruct the contents of the various rules of interpretation. To facilitate reference, the conclusions suggest a list of 44 rules, all of which can be invoked by appliers citing VCLT Articles 31-33.
Omics sudies of medicinal plants
Herbal drugs play a pivotal role in modern medicine and pharmaceutical care; however, only limited biotechnology applications have been seen in medicinal plants. Revolutions in high-throughput approaches emphasize omics approaches, such as genomics, transcriptomics, proteomics, and metabolomics. A volume in the Exploring Medicinal Plants series, this book provides a comprehensive and in-depth analysis of breakthroughs in high-throughput approaches for the research of medicinal plants.
Official Statistics 4.0 : Verified Facts for People in the 21st Century
Explores official statistics and their social function in modern societies. Digitisation and globalisation are creating completely new opportunities and risks, a context in which facts (can) play an enormously important part if they are produced with a quality that makes them credible and purpose-specific. In order for this to actually happen, official statistics must continue to actively pursue the modernisation of their working methods.
Ocean Wave Energy : Current Status and Future Prespectives
The authors of this reference provide an updated and global view on ocean wave energy conversion for wave energy developers as well as for students and professors. The book is orientated to the practical solutions that this new industry has found so far and the problems that any device needs to face. It describes the actual principles applied to machines that convert wave power in electricity. Additionally, an historical review, state of the art of modern systems, a full scale prototype experience, and future perspectives are given.
Objects, Components, Models and Patterns ; 46th International Conference, TOOLS EUROPE 2008, Zurich, Switzerland, June 30 - July 4, 2008. Proceedings
This book constitutes the thoroughly refereed proceedings of the 46th International Conference on Objects, Components, Models and Patterns, TOOLS EUROPE 2008, held in Zurich, Switzerland, in June/July 2008.TOOLS played a major role in the spread of object-oriented and component technologies. It has now broadened its scope beyond the original topics of object technology and component-based development to encompass all modern, practical approaches to software development.
Object-Oriented Data Structures Using Java ; 4th ed.
an essential resource for students learning data structures using the Java programming language. It presents both the traditional and modern data structure topics with an emphasis on problem-solving and object-oriented software design. Beginning early and continuing throughout the text, it introduces and expands upon the use of many Java features such as classes, objects, generics, polymorphism, packages, interfaces, library classes, inheritance, exceptions, and threads.
Nutrient Acquisition by Plants : An Ecological Perspective
Adaptation and evolution of terrestrial plants depend, to a large extent, on their ability to acquire nutrients. This is a modern and integrative treatment of the mechanisms controlling plant nutrient uptake and how plants respond to changes in the environment. The following key topics are covered: soil nutrient bioavailability; root responses to variations in nutrient supply; nitrogen fixation; regulation of nutrient uptake by internal plant demand; root characteristics; kinetics of nutrient uptake; root architecture; life span; mycorrhizae; responses to climate change. This integrated view helps us to understand the mechanisms that govern present-day plant communities and is indispensable in models designed to predict the response of plants to a changing climate.
Nutraceuticals for the treatment and prevention of sexual disorders
Covers diverse aspects of sexual dysfunctions and the role of nutraceutical therapeutics, applying both traditional knoweldge and modern evidence-based research. The new book focuses on the use of nutraceuticals on sexual disorders, highlighting the working solutions as well as open problems and future challenges in the use of nutraceuticals in sexual disorder research. Disucssing state-of-the-art developments and trends in this field, the book covers the use of antioxidants in stress-induced male infertility, the role of nutraceuticals in prostate cancer, male sex hormone disturbances, and the impact of nutraceuticals on male accessory organs. The book also addresses the use of nutraceuticals on female sexual disorders and remedial measures in treating breast cancer, cervical complications, pregnancy health and disorders, menstrual disturbances, female sex hormones, female infertility, and prevention of vaginal infections. The book also covers the use of nutraceuticals to combat general sexual disorders such as urinogenital complications, geriatric sexual functions, traditional nutraceuticals use for sexual disorders, the use of nutritional spices for sexual disorders, and the role of nutraceuticals on transgendered individuals.
Numerical Mathematics and Advanced Applications ; Proceedings of ENUMATH 2007, the 7th European Conference on Numerical Mathematics and Advanced Applications, Graz, Austria, September 2007
The European Conference on Numerical Mathematics and Advanced Applications (ENUMATH) is a series of meetings held every two years to provide a forum for discussion on recent aspects of numerical mathematics and their applications. These proceedings contain a selection of invited plenary lectures, papers presented in minisymposia and contributed papers. Topics include theoretical aspects of new numerical techniques and algorithms as well as of applications in engineering and science. The book will be useful for a wide range of readers, giving them an excellent overview of the most modern methods, techniques, algorithms and results in numerical mathematics, scientific computing and their applications.
Numerical Mathematics
Numerical mathematics is the branch of mathematics that proposes, develops, analyzes and applies methods from scientific computing to several fields including analysis, linear algebra, geometry, approximation theory, functional equations, optimization and differential equations. Other disciplines, such as physics, the natural and biological sciences, engineering, and economics and the financial sciences frequently give rise to problems that need scientific computing for their solutions. As such, numerical mathematics is the crossroad of several disciplines of great relevance in modern applied sciences, and can become a crucial tool for their qualitative and quantitative analysis.
Numerical analysis
Introduces readers to the theory and application of modern numerical approximation techniques. Providing an accessible treatment that only requires a calculus prerequisite, the authors explain how, why, and when approximation techniques can be expected to work-and why, in some situations, they fail. A wealth of examples and exercises develop readers' intuition, and demonstrate the subject's practical applications to important everyday problems in math, computing, engineering, and physical science disciplines.
Numeri e Crittografia
Number Theory is one of the most classic fields of Mathematics. The numbers he deals with are those that are called natural 0, 1, 2, ... and that we use since childhood to count. Seemingly simple and harmless, they nevertheless hide some of the most difficult and exciting mysteries of the whole of mathematics. Cryptography, on the other hand, is concerned with hiding the content of confidential communications from prying eyes and corresponds to widespread needs in our society. The Theory of Numbers can help Cryptography in these needs, thanks to the mysteries that still surround it. The text gives an account of this link. It first introduces Modern Cryptography, its goals and priorities. He then goes on to expose arguments of Number Theory, with particular reference to the two problems of recognizing prime numbers, and of decomposing a natural into its prime factors; for each of the two issues it provides a vast panorama of the algorithms that deal with it and try to solve it as effectively as possible. In particular, it presents the very recent AKS procedure for recognizing prime numbers. The book then returns to Cryptography and shows how ideas and methods of Number Theory apply to the construction of reliable procedures for the secure transmission of confidential information.
Number Theory ; Vol.15 : Tradition and Modernization
This book appears varied, they are unified by two underlying principles:first, making everything readable as a book, and second, making a smooth transition from traditional approaches to modern ones by providing a rich array of examples. The chapters are presented in quite different in depth and cover a variety of descriptive details.The book emphasizes a few common features such as functional equations for various zeta-functions, modular forms, congruence conditions, exponential sums, and algorithmic aspects.
Number Theory ; Vol. II : Analytic and Modern Tools
The central theme of this graduate-level number theory textbook is the solution of Diophantine equations, i.e., equations or systems of polynomial equations which must be solved in integers, rational numbers or more generally in algebraic numbers. This theme, in particular, is the central motivation for the modern theory of arithmetic algebraic geometry. In this text, this is considered through three aspects.
Number Theory ; Vol. I : Tools and Diophantine Equations
The central theme of this graduate-level number theory textbook is the solution of Diophantine equations, i.e., equations or systems of polynomial equations which must be solved in integers, rational numbers or more generally in algebraic numbers. This theme, in particular, is the central motivation for the modern theory of arithmetic algebraic geometry. In this text, this is considered through three aspects.
Number Theory : An Introduction to Mathematics ; Part B
This book attempts to provide such an understanding of the nature and extent of mathematics. It is a modern introduction to the theory of numbers, emphasizing its connections with other branches of mathematics. This part B is more advanced than the first and should give the reader some idea of the scope of mathematics today. The connecting theme is the theory of numbers. By exploring its many connections with other branches, we may obtain a broad picture.
Number Theory : An Introduction to Mathematics ; Part A
This book attempts to provide such an understanding of the nature and extent of mathematics. It is a modern introduction to the theory of numbers, emphasizing its connections with other branches of mathematics. This part A, which should be accessible to a first-year undergraduate, deals with elementary number theory.
Nucleic Acids Hybridization : Modern Applications
Several approaches, such as microarray hybridization, have become extremely popular tools for specialists in biochemistry and biomedicine, while the potential of many other advantageous techniques seems to be underestimated. Written by an international team of authors, this book details the current state-of-art in hybridization techniques. Coverage includes experimental protocols along with comprehensive and detailed method descriptions.
Nuclear Condensed Matter Physics with Synchrotron : Basic Principles, Methodology and Applications
This book provides a comprehensive introduction to the growing field of nuclear condensed matter physics with synchrotron radiation, a technique which finds numerous applications in fields such as magnetism, physics of surfaces and interfaces, lattice dynamics and more. Due to the enormous brilliance of modern synchrotron radiation sources, the method is particularly suited for the investigation of low-dimensional structures such as thin films and nanoparticles. The use of isotopic probe layers, for example, allows one to determine magnetic and vibrational properties with very high spatial resolution; focusing techniques and x-ray interference effects lead to a very high sensitivity for smallest amounts of material. The book is written on an introductory level with many examples employed to illustrate the special experimental possibilities.
