الصفحة 1
الصفحة 1
Notch Signaling in Embryology and Cancer : Notch Signaling in Cancer
This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.
Molecular Targeting in Oncology
In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer and is structured in a way so readers may begin with chapters that most interest them and work through the rest of the chapters in the order of their choice. The volume is divided into five sections that cover the most important elements of drug development. The first section focuses on approaches using targeted therapies to inhibit cell growth. The second section describes how clinicians are evaluating targeted therapies in specific organ systems. The third section illustrates how various classes of pharmacologic and immunologic agents are developed for individual molecular targets. The fourth section details new drugs that have novel mechanisms of action. The final section looks to the future of targeted therapeutics and includes chapters on appropriate patient selection, use of combination therapy, dealing with tumor cell resistance, and more. Comprehensive and cutting-edge, Molecular Targeting in Oncology is an essential reference for those working in the field.
Modern cryotherapy as cancer treatment
Despite the new development of cancer therapy we noticed that we still have a high mortality rate and it is of importance to introduce all types of new cancer therapies to our patients in Syria. Cryotherapy is a new old option and first used in skin cancer which we will discuss in our study and we will also a new diagnostic tool for the most aggressive cancer melanoma which may help doctors to identify at which stage we can start with cryotherapy by early detection of that cancer. Breast and prostate cancers are the most common and lethal for women and men respectively however we will also add breast cancer in men, and the application of cryotherapy in such tumors, and our interest about bone tumor was based on the fact of the expanses of bone marrow transplantation in our country so we need many types of cancer therapies to prevent patients from reaching this option.
Micrometastasis
Distant metastases are the main cause of cancer-related death. The onset of the metastatic process can now be assessed in cancer patients by the use of immunocytochemical and molecular methods that allow the identification of disseminated carcinoma cells in regional lymph nodes, peripheral blood or distant organs. There is increasing evidence that the detection and characterization of tumor cells present in bone marrow or peripheral blood can provide clinically important information. In this book, leading experts in the area of micrometastasis research provide an overview that summarizes the current state of research on micrometastatic disease in patients with solid tumors. In each chapter, the technical aspect as well as clinical relevance of micrometastasis detection is discussed. The book addresses basic researchers as well as clinicians involved in the treatment of cancer patients.
From Melanocytes to Malignant Melanoma: The Progression to Malignancy
Melanoma offers an excellent model for cancer biology and an opportunity to understand the progression of a normal skin cell-the melanocyte-to malignancy. In From Melanocytes to Melanoma: The Progression to Malignancy, leading researchers and clinicians join forces to explain how skin cancer develops from its benign precursor cell type.
Differential Diagnosis for the Dermatologist
When faced with a challenging dermatologic problem, physicians are often required to do a time-consuming search through large dermatologic texts to find the information on the necessary differential diagnosis. This comprehensive and concise Handbook of Differential Diagnosis for the Dermatologist will shorten this process to a matter of seconds.
Dépistage et cancers cutanés = Skin cancer screening
This work takes stock of the epidemiological aspects of these tumors in France and their clinical aspects. It offers an identification of risk markers and predisposing lesions specific to each tumor type. A strategy for the early diagnosis of carcinoma on the one hand and of melanoma on the other is proposed, relying, in particular for melanoma, on the new methods of care offered today to the patient.
Cytokines and Cancer
This volume provides a comprehensive review of the current knowledge on cytokines and cancer. Cytokines play a variety of roles in cancer, both as components of pathogenetic mechanisms, as well as agents used in the treatment of certain malignancies.The volume is divided in two sections. Section one focuses on current developments in the basic science field with particular emphasis on novel mechanisms of cytokine actions in malignant cells. The second section deals with translational and clinical research in the field, and many of the chapter authors were among the first to introduce several cytokines in the treatment of certain tumors.
Cornea and External Eye Disease : Corneal Allotransplantation, Allergic Disease and Trachoma
The 8 recurring volumes of the "Essentials in Ophthalmology" series cover the most recent developments in one of eight subspecialties in Ophthalmology.
Color Atlas of Melanocytic Lesions of the Skin
The purpose is to teach dermatologists how to increase diagnostic accuracy of pigmented lesions, especially melanoma, by using the dermatoscope. … The audience is dermatologists and dermatology residents
Compendium of Surface Microscopic and Dermoscopic Features
This unique guide provides a comprehensive, current, and accurate A-Z encyclopaedia to clarify the meaning of surface microscopic and dermoscopic terminology including a broad range of both melanocytic and non-melanocytic skin lesions.
Clinical nuclear medicine
Clinical Nuclear Medicine … focuses on the universal state of the art in both diagnostic and therapeutic radionuclide methodology. … This book is easily readable, with presentation of essential points and plentiful references, and the quality of the figures and tables is excellent. … is a useful guide to students, technologists, and practitioners in nuclear medicine and radiology, as well as to general physicians who request nuclear diagnosis or treatment. … will be a welcome contribution to the bookshelf of nuclear medicine or radiology clinics.
Cancer in adolescents and young adults
The chapters highlight the initial efforts of this Committee in addressing the scope of the problem of adolescent and young adult underrepresentation in clinical trials and offer evidence that such adiscrepancy may partially explain outcome differences.In addition, these chapters present information about biologic differences between specific cancer subtypes most common in younger children and those exhibited by the same cancers in adolescents and young adults, and offer plausible explanations for outcome differences as well as potential treatment strategies.
Cancer drug resistance
In Cancer Drug Resistance, leading scientists from the best academic institutions and industrial laboratories summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to a wide variety of anticancer therapeutics, as well as suggest new approaches to the biology of drug resistance that may afford new therapeutic opportunities.
Cancer and Pregnancy
This book is written by experts with clinical expertise on diagnosis, treatment, and follow-up of women with cancer during pregnancy. It provides a comprehensive review of data and an overview of psychological, ethical, and social aspects.
Brain Metastases
Brain metastases are the most dreaded complication of systemic cancer, affecting approximately 170,000 people a year, a far greater incidence than primary brain tumors. Advances in modern chemotherapy have led to an improved control of system cancers, often with agents that poorly penetrate the central nervous system, resulting in an increasing incidence of brain metastases. Traditional chemotherapy has had little impact on brain metastases. The main therapeutic option is radiation therapy, and in a small number of patients - surgery. However, refinements in all of these treatments offer some positive outcomes and an increased ability to stratify patients based on certain criteria.
