الصفحة 1
الصفحة 1
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Mathematics for Life Science and Medicine

Dynamical systems theory in mathematical biology has attracted much attention from many scientific directions. The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. The main topics include cancer treatment, dynamics of paroxysmal tachycardia, vector disease models, epidemic diseases and metapopulations, immune systems, pathogen competition and coexistence and the evolution of virulence and the rapid evolution of viruses within a host. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.

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Mathematics for Ecology and Environmental Sciences

Dynamical systems theory in mathematical biology has attracted much attention from many scientific directions. The purpose of this volume is to discuss the many rich and interesting properties of dynamical systems that appear in ecology and environmental sciences. The main topics include population dynamics with dispersal, nonlinear discrete population dynamics, structured population models, mathematical models in evolutionary ecology, stochastic spatial models in ecology, game dynamics and the chemostat model. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present important new results, and to inspire future contributions to mathematical modeling in ecology and environmental sciences.

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Interacting Stochastic Systems

The Research Network on "Interacting stochastic systems of high complexity" set up by the German Research Foundation aimed at exploring and developing connections between research in infinite-dimensional stochastic analysis, statistical physics, spatial population models from mathematical biology, complex models of financial markets or of stochastic models interacting with other sciences. This book presents a structured collection of papers on the core topics, written at the close of the 6-year programme by the research groups who took part in it. The structure chosen highlights the interweaving of certain themes and certain interconnections discovered through the joint work.

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Free Energy and Self-Interacting Particles

This book examines a system of parabolic-elliptic partial differential eq- tions proposed in mathematical biology, statistical mechanics, and chemical kinetics. In the context of biology, this system of equations describes the chemotactic feature of cellular slime molds and also the capillary formation of blood vessels in angiogenesis. There are several methods to derive this system. One is the biased random walk of the individual, and another is the reinforced random walk of one particle modelled on the cellular automaton. In the context of statistical mechanics or chemical kinetics, this system of equations describes the motion of a mean field of many particles, interacting under the gravitational inner force or the chemical reaction

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Current Themes in Theoretical Biology : A Dutch Perspective

The present volume originated in 2001 when we, together with our publishing editors at (then) Kluwer Academic Publishers, realized that the th following year the 50 volume of our journal Acta Biotheoretica would see the light. We felt that this milestone should not pass unnoticed and that the appropriate way to mark it would be the publication of a special volume of papers on theoretical biology. While editing this book during 2003 and early 2004, we realized that another milestone was not far off: in 2005 it will be 70 years ago that the journal was founded. We hope that the book lying before you will serve well to mark both events. The papers collected here have been written on invitation by representatives of the theoretical biology community in The Netherlands. They are intended to reflect the entire spectrum of topics on which Acta Biotheoretica publishes, ranging from philosophy of biology on one end to mathematical biology on the other. All chapters (except our own introductory one) have been peer reviewed according to the standards that are maintained with respect to regular submissions to Acta Biotheoretica.

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Mathematical Modelling of Biosystems

This volume is an interdisciplinary book, which introduces, in a very readable way, state of the art research in the fundamental topics of mathematical modelling of Biosystems. These topics include: the study of Biological Growth and its mechanisms, the coupling of pattern to form via theorems of Differential Geometry, the human immunodeficiency virus dynamics, the inverse folding problem and the possibility of analysing true protein backbone flexibility, the Biclustering techniques for the organization of microarray data, the analytical approach to the modelling of biomolecular structure via Steiner trees, the action of biocides on resistance mechanisms of mutated and phenotypic bacteria strains, a description of the fundamental processes for the distribution and abundances of species towards a unified theory of Ecology, and a special introduction to Protein Physics aiming to explain the all-or-none first order phase transitions from native to denatured states.

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Mathematical Modeling for the Life Sciences

Proposing a wide range of mathematical models that are currently used in life sciences may be regarded as a challenge, and that is precisely the challenge that this book takes up. Of course this panoramic study does not claim to offer a detailed and exhaustive view of the many interactions between mathematical models and life sciences. This textbook provides a general overview of realistic mathematical models in life sciences, considering both deterministic and stochastic models and covering dynamical systems, game theory, stochastic processes and statistical methods. Each mathematical model is explained and illustrated individually with an appropriate biological example. Finally three appendices on ordinary differential equations, evolution equations, and probability are added to make it possible to read this book independently of other literature.

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