الصفحة 1
الصفحة 1
Nuclear Import and Export in Plants and Animals
Nuclear Import and Export in Plants and Animals provides insight into the remarkable mechanisms of nuclear import and export. This book covers a range of topics from the nuclear pore structure, to nuclear import and export of macromolecules in plant and animal cells. In addition, the book covers the special cases of nuclear import of Agrobacterium T-DNA during plant genetic transformation, nuclear import and export of animal viruses, and nuclear intake of foreign DNA. A chapter on research methods to study nuclear transport concludes the book.
New Frontiers in Polymer Synthesis
It is generally accepted that a new material is often developed by ?nding a new synthesis method of reaction or a new reaction catalyst. Historically, a typical example may be referred to as a Ziegler–Natta catalyst, which has allowed large-scale production of petroleum-based polyole?ns since the middle of the 20th century. New polymer synthesis, therefore, will hopefully lead to creation of new polymer materials in the 21st century. This special issue contributed by three groups focuses on recent advances in polymer synthesis methods, which handle the cutting-edge aspects of the advanced technology.
New Aspects in Phosphorus Chemistry V
The use of polyphosphazenes as fluoroelastomers, flame retardants and self-extinguishing macromolecules, polymeric ionic conductors, biomaterials, and photosensitive polymeric compounds is outlined. This volume,as well as the four precedent volumes,describes only in part the huge number of original papers on phosphorus-related topics. Some further volumes will be necessary in the future to cover all aspects of this chemistry in perpetual rebirth.
Neutron Spin Echo in Polymer Systems
Neutron spin echo spectroscopy (NSE) provides the unique opportunity to unravel the molecular dynamics of polymer chains in space and time, covering most of the relevant length and time scales. This article reviews in a comprehensive form recent advances in the application of NSE to problems in polymer physics and describes in terms of examples expected future trends. The review commences with a description of NSE covering both the generic longitudinal field set-up as well as the resonance technique. Then, NSE results for homopolymers chains are presented, covering all length scales from the very local secondary J3-relaxation to large scale reptation. This overview is the core of the review. Thereafter the dynamics of more complex systems is addressed. Starting from polymer blends, diblock copolymers, gels, micelles, stars and dendrirners, rubbery electrolytes and biological macromolecules are discussed. Wherever possible the review relates the NSE findings to the results of other techniques, in particular emphasizing computer simulations.
NanoBiotechnology : BioInspired Devices and Materials of the Future
NanoBioTechnology: BioInspired Devices and Materials of the Future is a groundbreaking text that will assist scientists and students in learning the fundamentals and cutting-edge nature of this new and emerging science. Focusing on materials and building blocks for nanotechnology, leading scientists from around the world share their knowledge and expertise in this authoritative volume. The volume is broken into five sections. The first section presents an overview of nanotechnology and describes the many aspects of the field. Section 2 details biological materials serving as nanotemplates for bottom-up fabrication. Section 3 covers the use of biological macromolecules for electron transfer and computation. Section 4 presents a brief overview of the extensive and rapidly growing field of nanomedicine. Finally, Section 5 details de-novo designed structures and the various approaches different scientific groups take with molecular level training and language
Inorganic and Organometallic Macromolecules : Design and Applications
Polymers containing metals and metal-like atoms are essential materials for the extended opportunities and demands of the 21st century. This book describes the synthesis of some of these polymers and their potential application in many fields such as materials, biomedicine, engineering, communications, and ceramics.
Hydrogen bonded polymers
Control of polymeric structure is among the most important endeavours of modern macromolecular science. In particular, tailoring the positioning and strength of intermolecular forces within macromolecules by synthetic me- odsandthusgaining structuralcontrolover the'nalpolymeric materials has become feasible, resulting in the ?eld of supramolecular polymer science. - sides other intermolecular forces, hydrogen bonds are unique intermolecular forces enabling the tuning of material properties via self-assembly processes, The important contribution of hydrogen bondstotheareaofsupramole- lar polymer chemistry is de'nitely outstanding, most of all since the potency of hydrogen-bonding systems has been found to be unique in relation to other supramolecular interactions.
Guide to Biomolecular Simulations
Molecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role. Over the years, such simulations have become a central part of biophysics. Applications of molecular dynamics in biophysics range over many areas. They are used in the structure determination of macromolecules with x-ray and NMR data, the modelling of unknown structures from their sequence, the study of enzyme mechanisms, the estimation of ligand-binding free energies, the evaluation of the role of conformational change in protein function, and drug design for targets of known structures.
Fundamentals of Protein NMR Spectroscopy
NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs.
Forces, Growth and Form in Soft Condensed Matter : At the Interface between Physics and Biology
This volume comprises the proceedings of a NATO Advanced Study Institute held at Geilo, Norway, 24 March - 3 April 2003, the seventeenth ASI in a series held every two years since 1971. The objective of this ASI was to identify and discuss areas where synergism between modern physics, soft condensed matter and biology might be most fruitful. The main pedagogical approach was to have lecturers focussing on basic understanding of important aspects of the relative role of the various interaction- electrostatic, hydrophobic, steric, conformational, van der Waals etc. Soft condensed matter and the connection between physics and biology have been the themes of several earlier Geilo Schools. A return to these subjects thus allowed a fresh look and a possibility for defining new directions for research. Examples of soft materials, which were discussed at this ASI, included colloidal dispersions, gels, biopolymers and charged polymer solutions, polyelectrolytes, protein/membrane complexes, nucleic acids and their complexes. Indeed, most forms of condensed matter are soft and these substances are composed of aggregates and macromolecules, with interactions that are too weak and complex to form crystals spontaneously. A characteristic feature is that small external forces, slight perturbations in temperature, pressure or concentration, can all be enough to induce significant structural changes. Thermal fluctuations are almost by definition strong in soft materials and entropy is a predominant determinant of structure, so that disorder, slow dynamics and plastic deformation are the rule. Hence the phrase ‘soft condensed matter’ has been coined.
Comets and the Origin and Evolution of Life
Nine years after the publication of Comets and the Origin and Evolution of Life, one of the pioneering books in Astrobiology, this second edition revisits the role comets may have played in the origins and evolution of life. Recent analyses of Antarctic micrometeorites and ancient rocks in Australia and South Africa, the continuing progress in discovering complex organic macromolecules in comets, protostars and interstellar clouds, new insights into organic synthesis in comets, and numerical simulations of comet impacts on the Earth and other members of the solar system yield a spectacular wealth of new results.
Low Molecular Mass Gelators : Design, Self-Assembly, Function
Chapter 1 presents the physical principles of the growth mechanism of fiber and fiber network with LMGs, as treated on the basis of the heterogeneous nucleation model. in Chaps. 2 and 3, respectively. These chapters are intended to outline useful synthetic guidelines for the generation of an ever-increasing variety of molecular architectures within these two families of gelators. Recent developments in the chemistry of nucleobase-containing LMGs are described in Chap. 4. Hydrogen-bonding within these molecular systems involves complementary base pair formation, a process relevant to DNA double-helix formation The self-assembly of chiral organo- or hydrogelators is the subject of Chap. 5. result from the orthogonal self-assembly of liquid crystals and LMGs are presented in Chap. 6. The volume concludes with Chap. 7, a review of the emerging field of dendritic gels.
Biomacromolecules : Carbohydrates, lipids, proteins and nucleic acids
The first chapter looks at the structural formulas and cyclic forms of monosaccharides, as well as their synthesis and breakdown. Cyclization, enolization, isomerization, tautomerization, mutarotation, and epimerization are all briefly described. Examples of disaccharides and polysaccharides are also presented. The second chapter covers triglycerides, steroids, vitamins, and their constituents. The third chapter examines the primary structure of proteins, including amino acid properties, peptide bond formation, and peptide synthesis. It also addresses secondary, tertiary, and quaternary structures. The book concludes with a chapter on nucleic acids, which covers the chemistry of nucleosides and oligonucleotides as well as topics such as genetic code, DNA secret code, Polymerase Chain Reaction and DNA fingerprinting.
Biological Low-Voltage Scanning Electron Microscopy
Biological Low-Voltage Scanning Electron Microscopy is the first book to address both of these aspects of biological LVSEM. After providing a thorough description of the unique advantages and the operating constraints related to operating a scanning electron microscope at low beam voltage, the remainder of book focuses on the the best way to image all types of plant and animal cells and covers specimens that range from macromolecules to the surfaces revealed by de-embedding resin-embedded samples. Advanced specimen preparation techniques such as cryo-LVSEM, and immuno-gold-LVSEM are fully covered, as is x-ray microanalysis at low beam voltage and live-time stereo imaging. The preparative protocols provided represent the distilled essence of the experience of a group of world-renowned authors who have, for many decades, been instrumental in developing and applying new approaches to LVSEM to support their own biological research.
Bioanalytics : Analytical methods and concepts in biochemistry and molecular biology
Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids.
Analytical Ultracentrifugation VIII
This book presents a comprehensive collection of 21 contributions from leading scientists in this field covering a broad spectrum of topics and presenting recent progress concerning instrumentation, data analysis and modeling, biological systems, particles, colloids, synthetic macromolecules, interacting systems. Due to the versatility of this fascinating and powerful technique, information and original publications are widespread and comprehensive collections are rare. Therefore, this volume presents a valuable source for biologists, chemists, materials scientists, and physicists interested in most recent information, results and development related to this important analytical method.
Advanced computer simulation approaches for soft matter sciences II
This series presents critical reviews of the present and future trends in polymer and biopolymer science including chemistry, physical chemistry, physics and materials science. It is addressed to all scientists at universities and in industry who wish to keep abreast of advances in the topics covered.The second volume contains four contributions, and has a very strong topical focus on long range interactions.
Advanced computer simulation approaches for soft matter sciences I
Soft matter science is nowadays an acronym for an increasingly important class of materials, which ranges from polymers, liquid crystals, colloids up to complex macromolecular assemblies, covering sizes from the nanoscale up the microscale. Computer simulations have proven as an indispensable, if not the most powerful, tool to understand properties of these materials and link theoretical models to experiments. In this first volume of a small series recognized leaders of the field review advanced topics and provide critical insight into the state-of-the-art methods and scientific questions of this lively domain of soft condensed matter research.
