الصفحة 1
الصفحة 1
Novel Carrier Systems for Targeted and Controlled Drug Delivery
Presents novel carrier systems for the targeted and controlled drug delivery for the treatment of various diseases which are difficult to be treated with conventional drug delivery systems like cancer, autoimmune disorders, and emerging infectious diseases. It also reviews the origins and applications of stimuli-responsive polymer systems and polymer therapeutics such as polymer-protein and polymer-drug conjugates. The book also explores the potential applications of the parenteral route of administration for the delivery of active pharmaceutical substances with a narrow therapeutic index and poor bioavailability. Further, the book presents common routes of administration for the systemic delivery of peptides and proteins. It also examines the applications of various implantable systems in drug delivery. The book also covers the important colloidal drug delivery systems, including liposomes and niosomes and solid lipid nanoparticles, and nanostructured lipid carriers.
New methods for measuring and analyzing segregation
This book introduces new methods for measuring and analyzing residential segregation. It begins by placing all popular segregation indices in the “difference of group means” framework wherein index scores can be obtained as simple differences of group means on individual-level residential attainments scored from area racial composition. Drawing on the insight that in this framework index scores are additively determined by individual residential attainments, the book shows that the level of segregation in a given city can be equated to the effect of group membership (e.g., race) on individual residential attainments. This unifies separate research traditions in the field by joining the analysis of segregation at the aggregate level with the analysis of residential attainments for individuals.
Name Reactions : A Collection of Detailed Mechanisms and Synthetic Applications
The third edition contains major improvements over the previous edition. In addition to updated references, each reaction is now supplemented with two to three representative examples in synthesis to showcase its synthetic utility. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Furthemore, the subject index is significantly expanded.This is an excellent book for arrow pushing and learning organic name reactions as encountered in graduate school .
Multiple Testing Procedures and Applications to Genomics
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. The methods are applied to a range of testing problems in biomedical and genomic research, including the identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments.
Multimedia Retrieval
The single chapters of this textbook explain the general architecture of multimedia information retrieval systems; various metadata languages like Dublin Core, RDF, or MPEG; pattern recognition through Markov models, unsupervised learning, and pattern clustering; various indexing approaches to audio and video streams; interaction and control; the protection of content and user privacy; and search effectiveness and efficiency.
Multimedia Content Representation, Classification and Security ; International Workshop, MRCS 2006, Istanbul, Turkey, September 11-13, 2006, Proceedings
This book constitutes the refereed proceedings of the International Workshop on Multimedia Content Representation, Classification and Security, MRCS 2006, held in Istanbul, Turkey in September 2006. The 100 revised papers presented together with 4 invited lectures were carefully reviewed and selected from more than 190 submissions. The papers are organized in topical sections on biometric recognition, multimedia content security, steganography, watermarking, authentication, classification for biometric recognition, digital watermarking, content analysis and representation, 3D object retrieval and classification, representation, analysis and retrieval in cultural heritage, content representation, indexing and retrieval, content analysis and classification, feature extraction and classification, multimodal signal processing, 3D video and free viewpoint video, multimedia content transmission and classification, video and image processing, as well as video analysis and representation.
Morphosemantic Number : From Kiowa Noun Classes To UG Number Features
This volume presents: the foundations of a unified morphosemantic theory of number; insight into the flow of information from the lexicon, via syntax, into the morphology; wide-ranging topics: nominal semantics, noun classes, DP syntax, agreement, suppletion, complex morphology.
Modern Food Microbiology
With 30 revised and updated chapters, the new edition of this classic text brings benefits to professors and students alike who will find new sections on proteobacteria, bottled water, food sanitizers (eletrolyzed oxidating water, ozone, chlorine, activin, chitosans, endolysins, etc.), bicontrol, biosensors quorum sensing, molecular genetic methods of analysis, food safety objectives, noroviruses, and prions. The book builds on the trusted and established sections on food preservation by modified atmosphere, high pressure and pulsed electric field processing, food-borne pathogens, food regulations, fresh-cut produce, new food products, and risk assessment and analysis. In-depth references, appendixes, illustrations, index and thorough updating of taxonomies make this an essential for every food scientist.
Model Based Inference in the Life Sciences : A Primer on Evidence
The abstract concept of "information" can be quantified and this has led to many important advances in the analysis of data in the empirical sciences. This text focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The fundamental science question relates to the empirical evidence for hypotheses in this set—a formal strength of evidence. Kullback-Leibler information is the information lost when a model is used to approximate full reality. Hirotugu Akaike found a link between K-L information (a cornerstone of information theory) and the maximized log-likelihood (a cornerstone of mathematical statistics). This combination has become the basis for a new paradigm in model based inference. The text advocates formal inference from all the hypotheses/models in the a priori set—multimodel inference.
Mobile response ; 1st International Workshop on mobile information technology, for emergency response, mobile response 2007, Sankt Augustin, Germany, February 22-23, 2007. Revised Selected Papers
This book constitutes the thoroughly refereed post-proceedings of the First International Workshop on Mobile Information Technology for Emergency Response, MobileResponse 2007 held in Sankt Augustin, Germany in February 2007.
Microsoft Visual C# Step by Step
Guide to Microsoft Visual C# fundamentals with Visual Studio. Expand your expertiseand teach yourself the fundamentals of programming with the latest version of Visual C# with Visual Studio. If you are an experienced software developer, you'll get all the guidance, exercises, and code you need to start building responsive, scalable, cloud-connected applications that can run almost anywhere. Discover how to: Quickly start creating Visual C# code and projects with Visual Studio Work with variables, operators, expressions, methods, and program flow Build more robust apps with error, exception, and resource management Spot problems fast with the Visual Studio debugger Make the most of improvements to C# methods, parameters, and switch statements Master the C# object model, and create your own functional data structures Leverage advanced properties, indexers, generics, and collection classes Create Windows 10 apps that share data, collaborate, and use cloud services Integrate Cortana to voice-enable your applications Perform complex queries over object collections with LINQ
Microprocessor 2 : Communication in a digital system
Focuses more particularly on the first generations of microprocessors, that is to say those that handle integers in 4 and 8-bit formats. The first chapter presents the calculation function and reminds the memory function. The following is devoted to notions of calculation model and architecture. The concept of bus is then presented. Chapters 4 and 5 can then address the internal organization and operation of the microprocessor first in hardware and then software. The mechanism of the function call, conventional and interrupted, is more particularly detailed in a separate chapter. The book ends with a presentation of architectures of the first microcomputers for a historical perspective. The knowledge is presented in the most exhaustive way possible with examples drawn from current and old technologies that illustrate and make accessible the theoretical concepts. Each chapter ends if necessary with corrected exercises and a bibliography. The list of acronyms used and an index are at the end of the book.
Microorganisms in Foods 6 : Microbial Ecology of Food Commodities
The second edition of Microorganisms in Foods 6: Microbial Ecology of Food Commodities is intended for those primarily in applied aspects of food microbiology. For 17 commodity areas it describes the initial microbial flora and the prevalence of pathogens, the microbiological consequences of processing, typical spoilage patterns, episodes implicating those commodities with foodborne illness, and measures to control pathogens and limit spoilage. The control measures are presented in a standardized format in line with international developments in risk management. A comprehensive index has also been added.
Metric Structures for Riemannian and Non-Riemannian Spaces
The first stages of the new developments were presented in Gromov's course in Paris, which turned into the famous "Green Book" by Lafontaine and Pansu (1979). The present English translation of that work has been enriched and expanded with new material to reflect recent progress. Additionally, four appendices—by Gromov on Levy's inequality, by Pansu on "quasiconvex" domains, by Katz on systoles of Riemannian manifolds, and by Semmes overviewing analysis on metric spaces with measures—as well as an extensive bibliography and index round out this unique and beautiful book.
Methods in Nonlinear Analysis
Nonlinear analysis has developed rapidly in the last three decades. Theories, techniques and results in many different branches of mathematics have been combined in solving nonlinear problems. This book collects and reorganizes up-to-date materials scattered throughout the literature from the methodology point of view, and presents them in a systematic way. It contains the basic theories and methods with many interesting problems in partial and ordinary differential equations, differential geometry and mathematical physics as applications.There are five chapters that cover linearization, fixed-point theorems based on compactness and convexity, topological degree theory, minimization and topological variational methods. Each chapter combines abstract, classical and applied analysis. Particular topics included are bifurcation, perturbation, gluing technique, transversality, Nash–Moser technique, Ky Fan's inequality and Nash equilibrium in game theory, setvalued mappings and differential equations with discontinuous nonlinear terms, multiple solutions in partial differential equations, direct method, quasiconvexity and relaxation, Young measure, compensation compactness method and Hardy space, concentration compactness and best constants, Ekeland variational principle, infinite-dimensional Morse theory, minimax method, index theory with group action, and Conley index theory.
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006 ; Vol. 4191; 9th International Conference, Copenhagen, Denmark, October 1-6, 2006, Proceedings, Part II
T MICCAI papers are of high standard and have a long lifetime. In this v- ume as well as in the latest journal issues of Medical Image Analysis and IEEE Transactions on Medical Imaging papers cite previous MICCAIs including the ?rst MICCAI conference in Cambridge, Massachusetts, 1998. It is obvious that the community requires the MICCAI papers as archive material. Therefore the proceedingsofMICCAIarefrom2005andhenceforthbeing indexedbyMedline. Acarefulreviewandselectionprocesswasexecutedinordertosecurethebest possible program for the MICCAI 2006 conference. We received 578 scienti?c papers from which 39 papers were selected for the oral program and 193 papers for the poster program.
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006 ; Vol. 4190 ; 9th International Conference, Copenhagen, Denmark, October 1-6, 2006, Proceedings, Part I
MICCAI papers are of high standard and have a long lifetime. In this v- ume as well as in the latest journal issues of Medical Image Analysis and IEEE Transactions on Medical Imaging papers cite previous MICCAIs including the ?rst MICCAI conference in Cambridge, Massachusetts, 1998. It is obvious that the community requires the MICCAI papers as archive material. Therefore the proceedingsofMICCAIarefrom2005andhenceforthbeing indexedbyMedline. Acarefulreviewandselectionprocesswasexecutedinordertosecurethebest possible program for the MICCAI 2006 conference. We received 578 scienti?c papers from which 39 papers were selected for the oral program and 193 papers for the poster program.
Mechanosensitive Ion Channels
This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research.
Investigating the long-run relation between crypto-currencies and other assets
Crypto-currencies are financial assets with high volatility, which calls for an investigation of the long-run relation between crypto-currencies and other assets. The present study aims to explore the long-run relation between crypto-currencies and assets such as Gold and Oil Contracts For Differences (CFDs), the CBOE volatility index (VIX) and the Dow Jones Industrial Average Index. To this purpose, we analyze this relation using the Autoregressive Distributed Lag (ARDL) approach based on quarterly data for the period between first quarter of 2011 and first quarter of 2022, and monthly data for the period between Jan. 2018 and March 2022.
Introduction to Video Search Engines
Their book has a practical emphasis with the goal of bringing readers up to date on the state of the art in multimedia search technologies and systems. It explains the overall process of video content acquisition, indexing and retrieval with browsing, it provides overviews of constituent technologies such as information retrieval, Internet video systems, video and multimedia processing to extract index data, and it gives examples of research prototypes and existing commercial systems and describes their features.
