الصفحة 1
الصفحة 1
Nucleic Acids Hybridization : Modern Applications
Several approaches, such as microarray hybridization, have become extremely popular tools for specialists in biochemistry and biomedicine, while the potential of many other advantageous techniques seems to be underestimated. Written by an international team of authors, this book details the current state-of-art in hybridization techniques. Coverage includes experimental protocols along with comprehensive and detailed method descriptions.
Molecular Genetic Pathology
Molecular Genetic Pathology presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology.
Molecular Biomethods Handbook
Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Part A of the book describes nucleic acid methods, such as gene expression profiling, microarray analysis and quantitative PCR. In Part B, protein and cell-based methods are outlined, in subjects ranging from protein engineering to high throughput screening. Written by a well-established panel of research scientists, Molecular Biomethods Handbook, 2nd Edition provides an up-to-date collection of methods used regularly in the authors’ own research programs.
Methods in Gut microbial ecology for ruminants
As a result of various human activities, such as increase in human population,decrease in arable land due to soil degradation, urbanization, industrialization and associated increase in the demand for livestock products, dramatic changes are occurring in the global ruminant livestock sector. These changes includeshift inthesize of regional livestock populations and in the types of management and feeding systems under which ruminant livestock are held, and increased demand of a wider range of quality attributes from animal agriculture, not just of the products themselves but also of the methods used in their production. The livestock sector will need to respond to new challenges of increasing live stock productivity while protecting environment and human health and conservingbiodiversity and natural resources. The micro-organisms in the digestive tracts of ruminant livestock have a profound in?uence on the conversion offeedinto end products, which can impact on the- imal and theenvironment. As the livestock sector grows particularly in developing countries, there will be an increasing need to understand these processes for b- ter management and use ofbothfeed and other natural resources that underpinthe development of sustainable feeding systems.
Integration of AI and OR Techniques in Constraint Programming for Combinatorial Optimization Problems ; Vol.3524 : 2nd International Conference, CPAIOR 2005, Prague, Czech Republic, May 31 -- June 1, 2005
Intended primarily as a forum to focus on the integration and hybridization of the approaches of constraint programming (CP), arti?cial intelligence (AI), and operations research (OR) technologies for solving large-scale and complex real-life optimization problems. Therefore, CPAIOR is never far from industrial applications. The high number of submissions received this year, almost 100 papers, in witness to the interest of the research community in this conference. From these submissions, we chose 26 to be published in full in the proceedings. This volume includes summaries of the invited talks of CPAIOR: one from industry, one from the embedded system research community, and one from the operations research community.
Integration of AI and OR Techniques in Constraint Programming for Combinatorial Optimization Problems ; 5th International Conference, CPAIOR 2008 Paris, France, May 20-23, 2008 Proceedings
The 5th International Conference on Integration of AI and OR Techniques in Constraint Programming for Combinatorial Optimization Problems (CPAIOR 2008) was held in Paris, France May 20–23, 2008. The purpose of this conference series is to bring together researchers in the felds of constraint programming, artifcial intelligence, and operations research to explore ways of solving large-scale, practical optimization problems through integration and hybridization of the felds’ diferent techniques. Through the years, this research community is discovering that the felds have much in c- mon, and there has been tremendous richness in the resulting cross-fertilization of felds.
Hybrid metaheuristics ; Vol. 4030 ; 3rd International Workshop, HM 2006, Gran Canaria, Spain, October 13-14, 2006, Proceedings
The selection of papers for HM 2006 consolidated some of the mainstream issues that have emerged from the past editions. Firstly, there are prominent examples of e?ective hybrid techniques whose design and implementation were motivated by challenging real-world applications. We believe this is particularly important for two reasons: on the one hand, researchers are conscious that the primary goal of developing algorithms is to solve relevant real-life problems; on the other hand, the path towarde?cient solving methods for practical problems is a source of new outstanding ideas and theories. A second important issue is that the research community on metaheur- tics has become increasingly interested in and open to techniques and methods known from arti?cial intelligence (AI) and operations research (OR). So far, the most representative examples of such integration have been the use of AI/OR techniques as subordinates of metaheuristic methods. As a historical and - ymological note, this is in perfect accordance with the original meaning of a metaheuristic as a “general strategy controlling a subordinate heuristic. ” The awareness of the need for a sound experimental methodology is a third keypoint.
Hybrid metaheuristics ; Vol. 3636 ; 2nd International Workshop, HM 2005, Barcelona, Spain, August 29-30, 2005. Proceedings
Constitutes the refereed proceedings of the Second International Workshop on Hybrid Metaheuristics, HM 2005, held in Barcelona, Spain, in August 2005. In this book, the papers addresses topics such as: low-level hybridization, high-level hybridization, portfolio techniques, expert systems, co-operative search, taxonomy, terminology, and more.
Hybrid metaheuristics ; 5th International Workshop, HM 2008, Málaga, Spain, October 8-9, 2008. Proceedings
This book constitutes the refereed proceedings of the 5th International Workshop on Hybrid Metaheuristics, HM 2008, held in Malaga, Spain, in October 2008.The 14 revised full papers presented were carefully reviewed and selected from 33 submissions. The papers discuss specific aspects of combinations of metaheuristics and other solving techniques for tackling particular relevant constrained optimization problems, such as fiber optic networks, time tabling and freight train scheduling problems.
Hybrid metaheuristics ; 4th International Workshop,HM 2007, Dortmund, Germany, October 8-9, 2007, Proceedings
This book constitutes the refereed proceedings of the 4th International Workshop on Hybrid Metaheuristics, HM 2007, held in Dortmund, Germany. The 14 revised full papers discuss specific aspects of hybridization of metaheuristics, hybrid metaheuristics design, development and testing.
Hybrid Evolutionary Algorithms
Hybridization of evolutionary algorithms is getting popular due to their capabilities in handling several real world problems involving complexity, noisy environment, imprecision, uncertainty and vagueness. This edited volume is targeted to present the latest state-of-the-art methodologies in ’Hybrid Evolutionary Algorithms’. This book deals with the theoretical and methodological aspects, as well as various applications to many real world problems from science, technology, business or commerce. This volume comprises of 14 chapters including an introductory chapter giving the fundamental definitions and some important research challenges. Chapters were selected on the basis of fundamental ideas/concepts rather than the thoroughness of techniques deployed.
Genetics of Adaptation
What is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.
Flower Breeding and Genetics : Issues, Challenges and Opportunities for the 21st Century
This book provides a unique and valuable resource on the many issues and challenges facing flower breeders, as well as the industry at-large. In this volume, the first comprehensive assemblage of its kind, a team of 32 international authorities has contributed to make this book a ‘must-have’ reference to research and develop flower crops for the 21st century consumers. Part 1 of this book (flower breeding program issues) contains unique features of interest to horticultural professionals and students, include coverage of plant protection strategies, cultivar trialing methodology, germplasm collection/preservation, preventing invasiveness, and other timely topics. The collective body of knowledge for 24 flower crops (Part 2: Crop-specific Breeding and Genetics) represents the in-depth science and art of breeding technology available for bedding plants, flowering potted plants, cut flowers, and herbaceous perennials. Each author provides crop-specific history, evolution, biology, taxonomy, state-of-the-art breeding/genetics, classical/molecular technologies, species traits, interspecific hybridization, and directions for future development/enhancement.
Computational and Statistical Approaches to Genomics
Computational and Statistical Approaches to Genomics, 2nd Edition, aims to help researchers deal with current genomic challenges. During the three years after the publication of the first edition of this book, the computational and statistical research in genomics have become increasingly more important and indispensable for understanding cellular behavior under a variety of environmental conditions and for tackling challenging clinical problems. In the first edition, the organizational structure was: data à analysis à synthesis à application. In the second edition, the same structure remains, but the chapters that primarily focused on applications have been deleted.
Chromosomal alterations : Methods, results and importance in human health
Cytogenetics is a very important research tool in basic and applied research. The uses of cytogenetics in human-population monitoring, in biological dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer are topics discussed in this book. The book will help the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and therefore will be of interest to all who are interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.
Chemistry from First Principles
This book examines the appearance of matter in its most primitive form, from the vacuum and the diversity that results from the fusion of elementary units in the genesis of atomic matter; considers the empirical rules of chemical affinity that regulate the synthesis and properties of molecular matter; analyzes the compatibility of the theories of chemistry with the quantum and relativity theories of physics; formulates a consistent theory, based on clear physical pictures and manageable mathematics, to account for chemical concepts such as the structure and stability of atoms and molecules, the periodicity of nuclides and elements, valence states, activation and chemical reactivity, electronegativity and general covalency, the exclusion principle, electronic energy, orbital angular momentum and spin in relation to molecular shape, torsional rigidity, chirality and molecular modeling; explains the self-similarity between space-time, nuclear structure, covalent assembly, biological growth, planetary systems and galactic conformation.
Bird species : How they arise, modify and vanish
The average person can name more bird species than they think, but do we really know what a bird “species” is? This open access book takes up several fascinating aspects of bird life to elucidate this basic concept in biology. From genetic and physiological basics to the phenomena of bird song and bird migration, it analyzes various interactions of birds – with their environment and other birds. Lastly, it shows imminent threats to birds in the Anthropocene, the era of global human impact.This book brings together various disciplines involved in observing bird species come into existence, modify, and vanish. It is a rich resource for bird enthusiasts who want to understand various processes at the cutting edge of current research in more detail. At the same time it offers students the opportunity to see primarily unconnected, but booming big-data approaches such as genomics and biogeography meet in a topic of broad interest. Lastly, the book enables conservationists to better understand the uncertainties surrounding “species” as entities of protection.
Bioinformatics of genome regulation and structure II
The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
Bioarrays : From Basics to Diagnostics
Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics – that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
